在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Pig Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A), partial

  • 中文名稱:
    野豬PPARGC1A重組蛋白
  • 貨號:
    CSB-YP774721PI
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    野豬PPARGC1A重組蛋白
  • 貨號:
    CSB-EP774721PI
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    野豬PPARGC1A重組蛋白
  • 貨號:
    CSB-EP774721PI-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    野豬PPARGC1A重組蛋白
  • 貨號:
    CSB-BP774721PI
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    野豬PPARGC1A重組蛋白
  • 貨號:
    CSB-MP774721PI
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    PPARGC1A; PGC1; PGC1A; PPARGC1; Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PGC-1-alpha; PPAR-gamma coactivator 1-alpha; PPARGC-1-alpha
  • 種屬:
    Sus scrofa (Pig)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner. Also involved in the integration of the circadian rhythms and energy metabolism. Required for oscillatory expression of clock genes, such as ARNTL/BMAL1 and NR1D1, through the coactivation of RORA and RORC, and metabolic genes, such as PDK4 and PEPCK.
  • 基因功能參考文獻:
    1. Study investigated the molecular basis of such effects focusing on a commonly studied polymorphism in pig Pgc1alpha, which changes a cysteine at position 430 (WT) of the protein to a serine (C430S); found that differential O-GlcNAcylation of Pgc1alpha regulates PCK1 activity and this molecular mechanism could explain at least in part the epistatic interaction between both genes. PMID: 28644880
    2. Transcription of the gene was detected in adipose, muscle, kidney, liver, brain, heart and adrenal gland tissues, which is in agreement with the function of PPARGC1A in adaptive thermogenesis. PMID: 16276098
    3. The purpose of this study was to screen for new single nucleotide polymorphisms in exon 8 of the porcine PPARGC1A gene and to test their possible association with production traits. PMID: 17149556
    4. impact of PPARGC1A on energy and lipid metabolism in vivo, through several downstream target genes PMID: 19875886
    5. Proliferator-activated receptor-gamma coactivator-1A p.C430S genotypes significantly affected number (P < 0.05) and area (P < 0.01) of type I muscle fibre, and were significantly associated with muscle pH (P < 0.001) and lightness(P < 0.01). PMID: 20412126
    6. The *2690T>C and *2864T>C polymorphisms in PPARGC1A can be used as genetic markers for selection toward improved meat quality. PMID: 21748318
    7. The c.-2894G>A polymorphism in the 5' upstream region of the porcine PPARGC1A gene can be used as a meaningful molecular marker for simultaneous improvement of lean meat production and quality traits. PMID: 21769481
    8. PPARGC1A may play a key role in down-regulating lipid deposition, and the SNPs with differential genotype distribution among three breeds may be related to gene expression and fat deposition. PMID: 25004892
    9. Polymorphisms in PPARGC1A and CAPNS1 genes may affect meat quality traits. PMID: 21680104

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Nucleus, PML body.
  • 數據庫鏈接:


主站蜘蛛池模板: 少妇被多人c夜夜爽爽| 国产精品午夜爆乳美女视频| 俄罗斯少妇性xxxx另类| 最近日本免费观看高清视频| 亚洲第一区无码专区| 不卡无码av一区二区三区| 国产精品亚洲а∨怡红院| 中文字幕有码无码av| 国产精品久久久久久无毒不卡 | 在线视频国产网址你懂的| 国产午夜高潮熟女精品av软件| 欧美性猛交99久久久久99按摩| 天堂а√在线官网| 韩国无码色视频在线观看| 日本在线视频www色| 亚洲精品无码久久久久久| 国产高潮流白浆免费观看| 任你躁久久精品6| 久久人人97超碰caoporen| 精品亚洲成a人在线观看| 午夜福利国产成人无码gif动图| 国产亚洲精品久久综合阿香| 中文字幕乱码熟妇五十中出色欲| 亚州av综合色区无码一区| 高潮毛片无遮挡高清视频播放| 成年女人永久免费看片| 国产在线一区二区香蕉 在线| 99久久99久久精品国产片果冻| 亚洲国产一区二区波多野结衣| 久久精品人成免费| 国产精品 精品国内自产拍| 国产麻豆成人传媒免费观看| 国产a三级久久精品| h人成在线看免费视频| 欧美丰满熟妇xxxx性| 天天噜噜噜在线视频| 天天爽亚洲中文字幕| 国产又色又爽又黄的在线观看| 国产成人免费视频| 日韩人妻无码一区二区三区99| 午夜三级a三级三点|