在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Pig Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A), partial

  • 中文名稱:
    野豬PPARGC1A重組蛋白
  • 貨號:
    CSB-YP774721PI
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    野豬PPARGC1A重組蛋白
  • 貨號:
    CSB-EP774721PI
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    野豬PPARGC1A重組蛋白
  • 貨號:
    CSB-EP774721PI-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    野豬PPARGC1A重組蛋白
  • 貨號:
    CSB-BP774721PI
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    野豬PPARGC1A重組蛋白
  • 貨號:
    CSB-MP774721PI
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    PPARGC1A; PGC1; PGC1A; PPARGC1; Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PGC-1-alpha; PPAR-gamma coactivator 1-alpha; PPARGC-1-alpha
  • 種屬:
    Sus scrofa (Pig)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor on the uncoupling protein promoter. Can regulate key mitochondrial genes that contribute to the program of adaptive thermogenesis. Plays an essential role in metabolic reprogramming in response to dietary availability through coordination of the expression of a wide array of genes involved in glucose and fatty acid metabolism. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner. Also involved in the integration of the circadian rhythms and energy metabolism. Required for oscillatory expression of clock genes, such as ARNTL/BMAL1 and NR1D1, through the coactivation of RORA and RORC, and metabolic genes, such as PDK4 and PEPCK.
  • 基因功能參考文獻:
    1. Study investigated the molecular basis of such effects focusing on a commonly studied polymorphism in pig Pgc1alpha, which changes a cysteine at position 430 (WT) of the protein to a serine (C430S); found that differential O-GlcNAcylation of Pgc1alpha regulates PCK1 activity and this molecular mechanism could explain at least in part the epistatic interaction between both genes. PMID: 28644880
    2. Transcription of the gene was detected in adipose, muscle, kidney, liver, brain, heart and adrenal gland tissues, which is in agreement with the function of PPARGC1A in adaptive thermogenesis. PMID: 16276098
    3. The purpose of this study was to screen for new single nucleotide polymorphisms in exon 8 of the porcine PPARGC1A gene and to test their possible association with production traits. PMID: 17149556
    4. impact of PPARGC1A on energy and lipid metabolism in vivo, through several downstream target genes PMID: 19875886
    5. Proliferator-activated receptor-gamma coactivator-1A p.C430S genotypes significantly affected number (P < 0.05) and area (P < 0.01) of type I muscle fibre, and were significantly associated with muscle pH (P < 0.001) and lightness(P < 0.01). PMID: 20412126
    6. The *2690T>C and *2864T>C polymorphisms in PPARGC1A can be used as genetic markers for selection toward improved meat quality. PMID: 21748318
    7. The c.-2894G>A polymorphism in the 5' upstream region of the porcine PPARGC1A gene can be used as a meaningful molecular marker for simultaneous improvement of lean meat production and quality traits. PMID: 21769481
    8. PPARGC1A may play a key role in down-regulating lipid deposition, and the SNPs with differential genotype distribution among three breeds may be related to gene expression and fat deposition. PMID: 25004892
    9. Polymorphisms in PPARGC1A and CAPNS1 genes may affect meat quality traits. PMID: 21680104

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Nucleus, PML body.
  • 數據庫鏈接:


主站蜘蛛池模板: 9久9久女女热精品视频在线观看| 亚洲2022国产成人精品无码区| 亚洲aⅴ综合色区无码一区| 亚洲精品无码久久久久yw| 中文字幕韩国三级理论| 午夜影视免费| 3d动漫精品一区二区三区| 亚洲精品无码人妻无码| 怡红院成永久免费人视频新的| 亚洲人成亚洲人成在线观看| 国内揄拍国产精品人妻门事件| 伊人精品成人久久综合| 亚洲情a成黄在线观看| 国产精品久线在线观看| 九九九国产精品成人免费视频| 亚洲日韩va在线视频| 丰满岳妇乱一区二区三区| 在线天堂中文在线资源网| 欧美大片18禁aaa免费视频| 69国产精品成人aaaaa片| 自慰无码一区二区三区| 性欧美丰满熟妇xxxx性久久久| 国产情侣疯狂作爱系列| 午夜dj在线观看高清在线视频完整版| 久久精品99久久香蕉国产色戒 | 四虎永久在线精品免费视频观看 | 国产一区二区三区乱码在线观看| 国产精品老熟女露脸视频| 精品人妻系列无码专区| 国产成人无码一区二区三区| 中国女人和老外的毛片| 精品久久久久久国产潘金莲| 激情航班h版在线观看| 蜜桃av抽搐高潮一区二区| 免费观看女人高潮视频软件| 人妻系列无码专区无码中出| 亚洲精品乱码久久久久久久久久久久| 成年男人裸j照无遮挡无码| 精品无人区麻豆乱码1区2区| 亚洲日本va中文字幕久久| 男女啪啪做爰高潮无遮挡|