在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Pig Mu-type opioid receptor (OPRM1), partial

  • 中文名稱:
    野豬OPRM1重組蛋白
  • 貨號:
    CSB-YP842513PI1
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    野豬OPRM1重組蛋白
  • 貨號:
    CSB-EP842513PI1
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    野豬OPRM1重組蛋白
  • 貨號:
    CSB-EP842513PI1-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    野豬OPRM1重組蛋白
  • 貨號:
    CSB-BP842513PI1
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    野豬OPRM1重組蛋白
  • 貨號:
    CSB-MP842513PI1
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    OPRM1; Mu-type opioid receptor; M-OR-1; MOR-1
  • 種屬:
    Sus scrofa (Pig)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Receptor for endogenous opioids such as beta-endorphin and endomorphin. Receptor for natural and synthetic opioids including morphine, heroin, DAMGO, fentanyl, etorphine, buprenorphin and methadone. Agonist binding to the receptor induces coupling to an inactive GDP-bound heterotrimeric G-protein complex and subsequent exchange of GDP for GTP in the G-protein alpha subunit leading to dissociation of the G-protein complex with the free GTP-bound G-protein alpha and the G-protein beta-gamma dimer activating downstream cellular effectors. The agonist- and cell type-specific activity is predominantly coupled to pertussis toxin-sensitive G(i) and G(o) G alpha proteins, GNAI1, GNAI2, GNAI3 and GNAO1, and to a lesser extent to pertussis toxin-insensitive G alpha proteins GNAZ and GNA15. They mediate an array of downstream cellular responses, including inhibition of adenylate cyclase activity and both N-type and L-type calcium channels, activation of inward rectifying potassium channels, mitogen-activated protein kinase (MAPK), phospholipase C (PLC), phosphoinositide/protein kinase (PKC), phosphoinositide 3-kinase (PI3K) and regulation of NF-kappa-B. Also couples to adenylate cyclase stimulatory G alpha proteins. The selective temporal coupling to G-proteins and subsequent signaling can be regulated by RGSZ proteins, such as RGS9, RGS17 and RGS4. Phosphorylation by members of the GPRK subfamily of Ser/Thr protein kinases and association with beta-arrestins is involved in short-term receptor desensitization. Beta-arrestins associate with the GPRK-phosphorylated receptor and uncouple it from the G-protein thus terminating signal transduction. The phosphorylated receptor is internalized through endocytosis via clathrin-coated pits which involves beta-arrestins. The activation of the ERK pathway occurs either in a G-protein-dependent or a beta-arrestin-dependent manner and is regulated by agonist-specific receptor phosphorylation. Acts as a class A G-protein coupled receptor (GPCR) which dissociates from beta-arrestin at or near the plasma membrane and undergoes rapid recycling. Receptor down-regulation pathways are varying with the agonist and occur dependent or independent of G-protein coupling. Endogenous ligands induce rapid desensitization, endocytosis and recycling. Heterooligomerization with other GPCRs can modulate agonist binding, signaling and trafficking properties. Involved in neurogenesis.
  • 亞細胞定位:
    Cell membrane; Multi-pass membrane protein. Cell projection, axon. Perikaryon. Cell projection, dendrite. Endosome.
  • 蛋白家族:
    G-protein coupled receptor 1 family
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲色精品三区二区一区| 在线成人www免费观看视频| 风间由美性色一区二区三区| 成人性生交片无码免费看| 高潮内射免费看片| 国产成人亚洲高清一区| 性色av无码中文av有码vr| 无码人妻一区二区中文| 午夜毛片不卡高清免费看| 极品少妇被猛得白浆直流草莓视频| 在线播放亚洲第一字幕| 色婷婷久久综合中文久久一本| 国产av福利第一精品| 99在线精品视频高潮喷吹| 日本免费高清线视频免费| 无套内谢孕妇毛片免费看| 国产亚洲欧美日韩夜色凹凸成人 | 大又大粗又爽又黄少妇毛片| 人妻无码一区二区三区 tv| 国产精品亚洲精品日韩已满十八小 | 么公的好大好硬好深好爽视频 | 五十路熟女一区二区三区| 天堂8在线新版官网| 亚洲欧美日韩久久精品| 亚洲制服 视频在线观看| 国产成人啪精品视频网站午夜| 精品国产亚洲一区二区三区| 亚洲国产日韩欧美一区二区三区| 亚洲 综合 欧美在线视频| 亚洲综合久久无码色噜噜| 狠狠色狠狠色综合| 欧美三级不卡在线观看| 亚洲аv电影天堂网| 东京热人妻丝袜无码av一二三区观| 日本一区二区三区免费高清| 熟妇女人妻丰满少妇中文字幕| 欧美色欧美亚洲高清在线观看 | 一道久在线无码加勒比| 日本丰满熟妇videossex8k| 日韩av无码久久一区二区| 涩里番网污站|