在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Pig Heat shock protein HSP 90-alpha (HSP90AA1), partial

  • 中文名稱:
    野豬HSP90AA1重組蛋白
  • 貨號:
    CSB-YP010802PI
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    野豬HSP90AA1重組蛋白
  • 貨號:
    CSB-EP010802PI
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    野豬HSP90AA1重組蛋白
  • 貨號:
    CSB-EP010802PI-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    野豬HSP90AA1重組蛋白
  • 貨號:
    CSB-MP010802PI
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    HSP90AA1; HSP90A; HSPCAHeat shock protein HSP 90-alpha
  • 種屬:
    Sus scrofa (Pig)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interaction with various co-chaperone proteins or complexes, that act as adapters, simultaneously able to interact with the specific client and the central chaperone itself. Recruitment of ATP and co-chaperone followed by client protein forms a functional chaperone. After the completion of the chaperoning process, properly folded client protein and co-chaperone leave HSP90 in an ADP-bound partially open conformation and finally, ADP is released from HSP90 which acquires an open conformation for the next cycle. Plays a critical role in mitochondrial import, delivers preproteins to the mitochondrial import receptor TOMM70. Apart from its chaperone activity, it also plays a role in the regulation of the transcription machinery. HSP90 and its co-chaperones modulate transcription at least at three different levels. In the first place, they alter the steady-state levels of certain transcription factors in response to various physiological cues. Second, they modulate the activity of certain epigenetic modifiers, such as histone deacetylases or DNA methyl transferases, and thereby respond to the change in the environment. Third, they participate in the eviction of histones from the promoter region of certain genes and thereby turn on gene expression. Binds bacterial lipopolysaccharide (LPS) and mediates LPS-induced inflammatory response, including TNF secretion by monocytes. Antagonizes STUB1-mediated inhibition of TGF-beta signaling via inhibition of STUB1-mediated SMAD3 ubiquitination and degradation. Mediates the association of TOMM70 with IRF3 or TBK1 in mitochodria outer membrane which promotes host antiviral response.
  • 基因功能參考文獻:
    1. This study firstly found that host chaperone heat shock protein 90 (Hsp90) had a positive regulatory effect on the porcine circovirus type 2 infection cycle in vitro. PMID: 27553861
    2. Feed intake remains low whereas respiratory frequency and body temperature remain higher and expression of HSP90, CAT1, SGLT1 and GLUT4 increases in some tissues in pigs under chronic heat stress conditions. PMID: 27264891
    3. HSP90AA1 sperm content and the prediction of the boar ejaculate freezability. PMID: 20580074
    4. Hsp90 is a modulator of eNOS activity and vascular reactivity in the newborn piglet pulmonary circulation PMID: 17337508
    5. Apo-Hsp90 is in a conformational equilibrium between two open states that have never been described previously. PMID: 18215117
    6. Findings indicate an essential role for Hsp90 in nongenomic estrogen signaling in coronary artery smooth muscle cells. PMID: 19293389

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Cytoplasm. Melanosome. Cell membrane. Mitochondrion.
  • 蛋白家族:
    Heat shock protein 90 family
  • 組織特異性:
    Preferentially expressed in pituitary gland, brain, adrenal gland, and testis, in comparison to other tissues.
  • 數據庫鏈接:


主站蜘蛛池模板: 亚洲精品日本一区二区三区| 色老头在线一区二区三区| 国产亚洲精品久久久久久久| 午夜福利视频合集1000| 国产成人综合久久精品推最新| 成人a大片在线观看| 产精品视频在线观看免费 | 国产免费人成在线视频app| 国产精品玩偶在线观看| 狠狠色噜噜狠狠狠7777奇米| 国产网红主播无码精品| 亚洲αv无码一区二区三区四区| 国产欧美另类久久久精品丝瓜 | 久久视频这里只有精品在线观看| 久久综合伊人中文字幕| 四虎永久地址www成人| 大地资源中文第3页| 亚洲精品suv精品一区二区| 亚洲日韩乱码中文无码蜜桃臀网站| 国产香蕉尹人视频在线| 精品一区二区ww| 尤物色综合欧美五月俺也去| 久久99国产精品久久99| 国产自产v一区二区三区c| 国产无遮挡a片无码免费| 香港曰本韩国三级网站| 欧美成人国产精品高潮| 酒店大战丝袜高跟鞋人妻| 狠狠色成人综合网| 99久久精品费精品国产一区二| 人妻饥渴偷公乱中文字幕| 婷婷开心激情综合五月天 | 肉体裸交137日本大胆摄影| 99re8这里有精品热视频免费| 亚洲欧美精品suv| 丰满的少妇邻居中文bd| 人妻人人做人碰人人添| 日韩精品极品视频在线观看免费| 麻豆国产人妻欲求不满| 免费午夜福利不卡片在线播放| 亚洲天堂男人影院|