在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Pig Calcium/calmodulin-dependent protein kinase type II subunit delta (CAMK2D)

  • 中文名稱:
    Recombinant Pig Calcium/calmodulin-dependent protein kinase type II subunit delta(CAMK2D)
  • 貨號:
    CSB-YP839163PI
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Pig Calcium/calmodulin-dependent protein kinase type II subunit delta(CAMK2D)
  • 貨號:
    CSB-EP839163PI
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Pig Calcium/calmodulin-dependent protein kinase type II subunit delta(CAMK2D)
  • 貨號:
    CSB-EP839163PI-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Pig Calcium/calmodulin-dependent protein kinase type II subunit delta(CAMK2D)
  • 貨號:
    CSB-BP839163PI
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Pig Calcium/calmodulin-dependent protein kinase type II subunit delta(CAMK2D)
  • 貨號:
    CSB-MP839163PI
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    CAMK2D; Calcium/calmodulin-dependent protein kinase type II subunit delta; CaM kinase II subunit delta; CaMK-II subunit delta; EC 2.7.11.17
  • 種屬:
    Sus scrofa (Pig)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-499
  • 氨基酸序列
    ASTTTCTRF TDEYQLFEEL GKGAFSVVRR CMKIPTGQEY AAKIINTKKL SARDHQKLER EARICRLLKH PNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI LESVNHCHLN GIVHRDLKPE NLLLASKSKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY LSPEVLRKDP YGKPVDMWAC GVILYILLVG YPPFWDEDQH RLYQQIKAGA YDFPSPEWDT VTPEAKDLIN KMLTINPAKR ITASEALKHP WICQRSTVAS MMHRQETVDC LKKFNARRKL KGAILTTMLA TRNFSAAKSL LKKPDGVKES TESSNTTIED EDVKARKQEI IKVTEQLIEA INNGDFEAYT KICDPGLTAF EPEALGNLVE GMDFHRFYFE NALSKSNKPI HTIILNPHVH LVGDDAACIA YIRLTQYMDG SGMPKTMQSE ETRVWHRRDG KWQNVHFHRS GSPTVPIKPS CIPNGKENFS GSTSLWQNI
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Calcium/calmodulin-dependent protein kinase involved in the regulation of Ca(2+) homeostatis and excitation-contraction coupling (ECC) in heart by targeting ion channels, transporters and accessory proteins involved in Ca(2+) influx into the myocyte, Ca(2+) release from the sarcoplasmic reticulum (SR), SR Ca(2+) uptake and Na(+) and K(+) channel transport. Targets also transcription factors and signaling molecules to regulate heart function. In its activated form, is involved in the pathogenesis of dilated cardiomyopathy and heart failure. Contributes to cardiac decompensation and heart failure by regulating SR Ca(2+) release via direct phosphorylation of RYR2 Ca(2+) channel on 'Ser-2808'. In the nucleus, phosphorylates the MEF2 repressor HDAC4, promoting its nuclear export and binding to 14-3-3 protein, and expression of MEF2 and genes involved in the hypertrophic program. Is essential for left ventricular remodeling responses to myocardial infarction. In pathological myocardial remodeling acts downstream of the beta adrenergic receptor signaling cascade to regulate key proteins involved in ECC. Regulates Ca(2+) influx to myocytes by binding and phosphorylating the L-type Ca(2+) channel subunit beta-2 CACNB2. In addition to Ca(2+) channels, can target and regulate the cardiac sarcolemmal Na(+) channel Nav1.5/SCN5A and the K+ channel Kv4.3/KCND3, which contribute to arrhythmogenesis in heart failure. Phosphorylates phospholamban (PLN/PLB), an endogenous inhibitor of SERCA2A/ATP2A2, contributing to the enhancement of SR Ca(2+) uptake that may be important in frequency-dependent acceleration of relaxation (FDAR) and maintenance of contractile function during acidosis. May participate in the modulation of skeletal muscle function in response to exercise, by regulating SR Ca(2+) transport through phosphorylation of PLN/PLB and triadin, a ryanodine receptor-coupling factor.
  • 亞細胞定位:
    Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family, CaMK subfamily
  • 數據庫鏈接:


主站蜘蛛池模板: 色一情一乱一伦一视频免费看| av无码免费一区二区三区| 欧美老熟妇欲乱高清视频 | 精品人妻大屁股白浆无码| 欧洲美洲精品一区二区三区| 久久婷婷五月综合色俺也想去| 国产一区二区三区不卡在线观看| 少妇下面好紧好多水真爽播放 | 国产女爽爽精品视频天美传媒| 中文字幕久久综合伊人| 亚洲国产成人精品无码区花野真一 | 亚洲精品无码不卡av| 亚洲日本在线电影| 对白脏话肉麻粗话av| 青青草无码伊人久久| 午夜成人性刺激免费视频| 曰本无码人妻丰满熟妇啪啪 | 久久综合一色综合久久小蛇| 国产360激情盗摄全集| 精品国产va久久久久久久冰| 国产精品v欧美精品∨日韩| 国产亚洲精品欧洲在线视频| 手机看片精品国产福利| 精品综合久久久久久98| 少妇把腿扒开让我爽爽视频| 曰本大码熟中文字幕| 日日噜噜夜夜狠狠va视频| 国产午夜精品av一区二区| 国产日产欧产精品精品| 四虎精品国产永久在线观看| 最近日本免费观看高清视频| 含紧一点h边做边走动免费视频| 国产成人乱色伦区| 99久久伊人精品综合观看| 无遮挡裸体免费视频尤物| 亚洲最大成人综合网720p| 成人a毛片视频免费看| 夜夜爽日日澡人人添| 处破痛哭a√18成年片免费| 激情综合婷婷丁香五月情| 内射合集对白在线|