在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Orcinus orca Interleukin-6 (IL6)

  • 中文名稱:
    Recombinant Orcinus orca Interleukin-6(IL6)
  • 貨號:
    CSB-YP630696OEP
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Orcinus orca Interleukin-6(IL6)
  • 貨號:
    CSB-EP630696OEP
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Orcinus orca Interleukin-6(IL6)
  • 貨號:
    CSB-EP630696OEP-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Orcinus orca Interleukin-6(IL6)
  • 貨號:
    CSB-BP630696OEP
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Orcinus orca Interleukin-6(IL6)
  • 貨號:
    CSB-MP630696OEP
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    IL6Interleukin-6; IL-6; Fragment
  • 種屬:
    Orcinus orca (Killer whale)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區(qū)域:
    22-205
  • 氨基酸序列
    GPLGEDFKD DTTSDRLYLT SPDKTEALIK YILGKISAMR KEMCEKYDKC ENSKEALAEN NLNLPKMAEK DGCFQSGFNQ ETCLMRITTG LLEYQIYLDY LQNEYEGDKE AIEAVQISSK ALAQILRQKV KNPDEVTTPD PTTNASLMNN LQSQNDDWMK NTKIILILRS LENFLQFSLR AIRIK
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.; IL6 is a potent inducer of the acute phase response. Rapid production of IL6 contributes to host defense during infection and tissue injury, but excessive IL6 synthesis is involved in disease pathology. In the innate immune response, is synthesized by myeloid cells, such as macrophages and dendritic cells, upon recognition of pathogens through toll-like receptors (TLRs) at the site of infection or tissue injury. In the adaptive immune response, is required for the differentiation of B cells into immunoglobulin-secreting cells. Plays a major role in the differentiation of CD4(+) T cell subsets. Essential factor for the development of T follicular helper (Tfh) cells that are required for the induction of germinal-center formation. Required to drive naive CD4(+) T cells to the Th17 lineage. Also required for proliferation of myeloma cells and the survival of plasmablast cells.; Acts as an essential factor in bone homeostasis and on vessels directly or indirectly by induction of VEGF, resulting in increased angiogenesis activity and vascular permeability. Induces, through 'trans-signaling' and synergistically with IL1B and TNF, the production of VEGF. Involved in metabolic controls, is discharged into the bloodstream after muscle contraction increasing lipolysis and improving insulin resistance. 'Trans-signaling' in central nervous system also regulates energy and glucose homeostasis. Mediates, through GLP-1, crosstalk between insulin-sensitive tissues, intestinal L cells and pancreatic islets to adapt to changes in insulin demand. Also acts as a myokine. Plays a protective role during liver injury, being required for maintenance of tissue regeneration. Also has a pivotal role in iron metabolism by regulating HAMP/hepcidin expression upon inflammation or bacterial infection. Through activation of IL6ST-YAP-NOTCH pathway, induces inflammation-induced epithelial regeneration.
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    IL-6 superfamily


主站蜘蛛池模板: 老子影院午夜伦手机不四虎卡| 亚洲人成伊人成综合网久久久| 99久久国产露脸精品| 久久久婷婷五月亚洲97号色| 性xxxxx欧美极品少妇| 在线看片无码永久av| 开心久久婷婷综合中文字幕| 亚洲欧洲日产国码无码| 日韩一区二区三区射精| 两根大肉大捧一进一出好爽视频 | 巨胸不知火舞露双奶头无遮挡| 人妻精品人妻无码一区二区三区| 97精品久久天干天天| 老熟妇高潮喷了╳╳╳| 少妇伦子伦精品无吗| 伊人色综合九久久天天蜜桃| 99久久精品免费看国产一区二区| 四虎影成人精品a片| 日韩v亚洲v欧美v精品综合| 亚洲国产欧美日韩精品一区二区三区| 日韩精品中文字幕无码专区| 亚洲色www永久网站| 成熟妇女性成熟满足视频| 亚洲国产av无码综合原创国产| 老司机久久精品最新免费| 免费观看又色又爽又黄的崩锅| 少妇粉嫩小泬喷水视频www| 久久日本片精品aaaaa国产| 亚洲制服丝袜自拍中文字幕| 日本国产网曝视频在线观看| 无码av天天av天天爽| 国精产品一二三区传媒公司| 国产精品夜夜春夜夜爽久久小说| 精品国产福利久久久| 亚洲欧美成人a∨观看| 精品一区二区ww| 免费久久99精品国产自在现线| 国产麻传媒精品国产av| 亚洲乱码中文字幕小综合| 中文字幕无码人妻丝袜| 亚洲一区激情校园小说|