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  4. Recombinant Nematostella vectensis Neurotoxin Nv1-116.28.1 (v1g113139)

Recombinant Nematostella vectensis Neurotoxin Nv1-116.28.1 (v1g113139)

  • 中文名稱：
    Recombinant Nematostella vectensis Neurotoxin Nv1-116.28.1 (v1g113139)
  • 貨號：
    CSB-YP544147NGO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Nematostella vectensis Neurotoxin Nv1-116.28.1 (v1g113139)
  • 貨號：
    CSB-EP544147NGO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Nematostella vectensis Neurotoxin Nv1-116.28.1 (v1g113139)
  • 貨號：
    CSB-EP544147NGO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Nematostella vectensis Neurotoxin Nv1-116.28.1 (v1g113139)
  • 貨號：
    CSB-BP544147NGO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Nematostella vectensis Neurotoxin Nv1-116.28.1 (v1g113139)
  • 貨號：
    CSB-MP544147NGO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    v1g113139
  • Uniprot No.：
  • 別名：
    v1g113139; N.vectensis toxin 1 3; Nv1; Delta-edwarditoxin-Nvc1c; Delta-EWTX-Nvc1c; Delta-edwarditoxin-Nvc1d; Delta-EWTX-Nvc1d; Neurotoxin Nv1-116.28.1; Neurotoxin Nv1-13; Neurotoxin Nv1-15; Neurotoxin Nv1-17; Neurotoxin Nv1-18; Neurotoxin Nv1-19; Neurotoxin Nv1-2; Neurotoxin Nv1-4; Neurotoxin Nv1-5; Neurotoxin Nv1-8
  • 種屬：
    Nematostella vectensis (Starlet sea anemone)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    39-85
  • 氨基酸序列
    GI PCACDSDGPD IRSASLSGIV WMGSCPSGWK KCKSYYSIVA DCCNQ
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Binds to site 3 of voltage-gated sodium channels and inhibits the inactivation process. Is highly active on DmNav1/TipE (drosophila) and is only extremely weakly active on rat Nav1.4-beta-1/SCN4A-SCN1B, and on human Nav1.5-beta-1/SCN5A-beta-1. This reveals high specificity for arthropod over mammalian channels. In vivo, when released into the medium, this recombinant toxin induces impaired swimming, paralysis and death of the crustacean A.nauplii within several hours. Also causes paralysis of cherry shrimps immediately after injection at very low doses. Its effect on zebrafish (D.rerio) larvae is also rapid, since it induces tail twitching accompanied by impaired swimming after 20 minutes and complete paralysis within 45 minutes. It has also been observed to cause death of zebrafish larvae within 1 hour.
  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    Sea anemone sodium channel inhibitory toxin family, Type II subfamily
  • 組織特異性：
    Expressed in ectodermal glands and in clumps outside of the extodermal layer. Is not expressed in nematocytes. In adult female tissues, shows similar expression levels in mesenteries (gametes-producing tissue), tentacles, pharynx and physa.
  • 數(shù)據(jù)庫鏈接：


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