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Recombinant Neisseria meningitidis serogroup B Quinolinate synthase (nadA)

  • 中文名稱:
    腦膜炎奈瑟菌血清組nadA重組蛋白
  • 貨號:
    CSB-YP878213NGG
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    腦膜炎奈瑟菌血清組nadA重組蛋白
  • 貨號:
    CSB-EP878213NGG-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    腦膜炎奈瑟菌血清組nadA重組蛋白
  • 貨號:
    CSB-BP878213NGG
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    腦膜炎奈瑟菌血清組nadA重組蛋白
  • 貨號:
    CSB-MP878213NGG
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    nadA
  • Uniprot No.:
  • 別名:
    nadA; NMB0394; Quinolinate synthase A; EC 2.5.1.72
  • 種屬:
    Neisseria meningitidis serogroup B (strain MC58)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-370
  • 氨基酸序列
    MQTAARRSFD YDMPLIQTPT SACQIRQAWA KVADTPDRET ADRLKDEIKA LLKEKNAVLV AHYYVDPLIQ DLALETGGCV GDSLEMARFG AEHEAGTLVV AGVRFMGESA KILCPEKTVL MPDLEAECSL DLGCPEEAFS AFCDQHPDRT VVVYANTSAA VKARADWVVT SSVALEIVSY LKSRGEKLIW GPDRHLGDYI CRETGADMLL WQGSCIVHNE FKGQELAALK AEHPEAVVLV HPESPQSVIE LGDVVGSTSK LLKAAVSRPE KKFIVATDLG ILHEMQKQAP DKQFIAAPTA GNGGSCKSCA FCPWMAMNSL GGIKYALTSG RNEILLDRKL GEAAKLPLQR MLDFAAGLKK KDVFNGMGPA
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
  • 基因功能參考文獻:
    1. Data show that a protective conformational epitope is located in the head of Neisserial adhesin A (NadA). PMID: 25404323
    2. The prevalence and genetic diversity of pilE and nadA were investigated in the prevalent serogroups and clonal complexes of N. meningitidis isolated in China. PMID: 23290624
    3. The authors demonstrate by reporter gene fusion assays that alterations of the FarR binding site within the nadA promoter are sufficient to induce transcription of nadA. PMID: 21292554
    4. Our results suggest that NadA expression is under both stochastic and tight environmental-sensing regulatory control PMID: 20041170
    5. NmFarR is a negative transcriptional regulator of the adhesin/invasin NadA. PMID: 19400792

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  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Quinolinate synthase A family, Type 1 subfamily
  • 數據庫鏈接:

    KEGG: nme:NMB0394

    STRING: 122586.NMB0394



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