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Recombinant Murine adenovirus A serotype 1 Early E1A 21 kDa protein

  • 中文名稱:
    Recombinant Murine adenovirus A serotype 1 Early E1A 21 kDa protein
  • 貨號:
    CSB-YP320118MUS
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Murine adenovirus A serotype 1 Early E1A 21 kDa protein
  • 貨號:
    CSB-EP320118MUS
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Murine adenovirus A serotype 1 Early E1A 21 kDa protein
  • 貨號:
    CSB-EP320118MUS-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Murine adenovirus A serotype 1 Early E1A 21 kDa protein
  • 貨號:
    CSB-BP320118MUS
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Murine adenovirus A serotype 1 Early E1A 21 kDa protein
  • 貨號:
    CSB-MP320118MUS
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    N/A
  • Uniprot No.:
  • 別名:
    Early E1A 21 kDa protein
  • 種屬:
    Murine adenovirus A serotype 1 (MAdV-1) (Murine adenovirus 1)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-200
  • 氨基酸序列
    MSRLLRLSLS SRVWLAAQEA TRNVSEDPVV CRTPWDGSPT CTAVRVVRAE VLADGTMDLD IVFPEAAVQA VFSRTPWQDS TTATSAEEPS ASTDSISSDP LPISCVESFE DMDLRCYEQL SPSPESIETI EVFPPCSTCG GHEVNGFCSL CYLRGLTDLL PQADDAGEAE VPDESAKDLC FMDLLTWAME DKTECSRHDE
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    E1A protein has both transforming and trans-activating activities. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle. Disrupts the function of host retinoblastoma protein RB1/pRb and isoform early E1A 26 kDa protein stabilizes TP53, which are key regulators of the cell cycle. Induces the disassembly of the E2F1 transcription factors from RB1 by direct competition for the same binding site on RB1, with subsequent transcriptional activation of E2F1-regulated S-phase genes. Inactivation of the ability of RB1 to arrest the cell cycle is critical for cellular transformation, uncontrolled cellular growth and proliferation induced by viral infection. Stimulation of progression from G1 to S phase allows the virus to efficiently use the cellular DNA replicating machinery to achieve viral genome replication.
  • 數據庫鏈接:

    KEGG: vg:1732772



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