在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse cAMP-dependent protein kinase catalytic subunit beta (Prkacb)

Recombinant Mouse cAMP-dependent protein kinase catalytic subunit beta (Prkacb)

  • 中文名稱：
    小鼠Prkacb重組蛋白
  • 貨號(hào)：
    CSB-YP018689MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Prkacb重組蛋白
  • 貨號(hào)：
    CSB-EP018689MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Prkacb重組蛋白
  • 貨號(hào)：
    CSB-EP018689MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Prkacb重組蛋白
  • 貨號(hào)：
    CSB-BP018689MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Prkacb重組蛋白
  • 貨號(hào)：
    CSB-MP018689MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Prkacb; Pkacb; cAMP-dependent protein kinase catalytic subunit beta; PKA C-beta; EC 2.7.11.11
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    2-351
  • 氨基酸序列
    GNTAIAKKG SEVESVKEFL AKAKEDFLRK WENPPPSNAG LEDFERKKTL GTGSFGRVML VKHKATEQYY AMKILDKQKV VKLKQIEHTL NEKRILQAVE FPFLVRLEYS FKDNSNLYMV MEYVPGGEMF SHLRRIGRFS EPHARFYAAQ IVLTFEYLHS LDLIYRDLKP ENLLIDHQGY IQVTDFGFAK RVKGRTWTLC GTPEYLAPEI ILSKGYNKAV DWWALGVLIY EMAAGYPPFF ADQPIQIYEK IVSGKVRFPS HFSSDLKDLL RNLLQVDLTK RFGNLKNGVS DIKTHKWFAT TDWIAIYQRK VEAPFIPKFR GSGDTSNFDD YEEEEIRVSI TEKCGKEFCE F
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates GPKOW which regulates its ability to bind RNA.
  • 基因功能參考文獻(xiàn)：
    1. We suggest a role of the PRKACB gene splice variant Cbeta2 in regulating innate as well as adaptive immune sensitivity in vivo. PMID: 28837222
    2. Gli2 and Gli3 are dephosphorylated and activated in cilia and that impaired Gli2 and Gli3 processing in Ta3 mutant is at least in part due to a decrease in Gli2 and Gli3 phosphorylation. PMID: 28673820
    3. Studies identified three novel alternatively spliced transcript variants of the mouse protein kinase A catalytic beta subunit (Cbeta) gene designated Cbeta5, Cbeta6 and Cbeta7. PMID: 22151102
    4. crystal structure of the catalytic subunit in complex with ADP, aluminum fluoride, Mg2+ ions and a substrate peptide was determined at 2.0 A resolution PMID: 11896404
    5. Murine lymphoid tissues express a protein that is a homologue of human and bovine Cbeta2 PMID: 16889664
    6. PKCbetaII is a target for colon cancer chemoprevention and the PKCbeta-selective inhibitor enzastaurin may represent an effective chemopreventive agent in patients at high risk for colon cancer. PMID: 19221092
    7. Protein kinase A, C beta subunit is not essential for neuronal development or function but may play a more subtle role in memory that is modulated by strain-specific genetic modifiers. PMID: 12139926

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Cell membrane. Membrane; Lipid-anchor. Nucleus.
  • 蛋白家族：
    Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily
  • 組織特異性：
    Isoform 1 is found in all tissues examined, with the highest expression in the brain and very low levels in the testis. Isoform 2 is strongly expressed in the brain, in the prelimbic and insular cortex. Isoform 3 is also found only in the brain, but at ve
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 日韩精品无码免费专区网站| 色诱久久久久综合网ywww| av人摸人人人澡人人超碰妓女| 亚洲一区二区三区乱码在线欧洲| 亚洲人成网7777777国产| 99久久精品国产一区二区蜜芽| 在线观看欧美一区二区三区| 18禁黄网站禁片无遮挡观看| 国内精品一区二区三区不卡| 成人女人看片免费视频放人| 国产香蕉视频在线播放| 精品毛片乱码1区2区3区| 色噜噜狠狠成人中文综合| 老司机午夜福利av无码特黄a| 性欧美vr高清极品| 亚洲精品久久久久久无码色欲四季| 日本孕妇潮喷高潮视频| 亚洲综合天堂一区二区三区| 亚洲a∨无码一区二区三区| 欧美人与动性xxxxx杂性| 国内少妇偷人精品免费| 日韩精品无码久久久久久| 狂野欧美激情性xxxx按摩| 午夜影视免费| 亚洲精品午夜无码专区| 精品偷拍被偷拍在线观看| 国产午夜无码片在线观看| 色135综合网| 亚洲精品55夜色66夜色| 国产精品无码一区二区牛牛| 欧美牲交a欧美牲交aⅴ| 亚洲精品国产a久久久久久| 久久/这里只精品热在线获取| 双腿高潮抽搐喷白浆视频| 亚洲精品揄拍自拍首页一| 苍井空张开腿实干12次| 久久熟妇人妻午夜寂寞影院| 邪恶肉肉全彩色无遮盖| 男人扒开女人腿桶到爽免费 | 玩弄放荡人妻一区二区三区| 日本十八禁黄无遮禁视频免费|