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  4. Recombinant Mouse WD repeat-containing protein 41 (Wdr41)

Recombinant Mouse WD repeat-containing protein 41 (Wdr41)

  • 中文名稱：
    小鼠Wdr41重組蛋白
  • 貨號：
    CSB-YP663654MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Wdr41重組蛋白
  • 貨號：
    CSB-EP663654MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Wdr41重組蛋白
  • 貨號：
    CSB-EP663654MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Wdr41重組蛋白
  • 貨號：
    CSB-BP663654MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Wdr41重組蛋白
  • 貨號：
    CSB-MP663654MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Wdr41
  • Uniprot No.：
  • 別名：
    Wdr41; WD repeat-containing protein 41
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-460
  • 氨基酸序列
    MLRWLIGGGR EPQGLAEKAA LQTIGEDQGQ NPYTELLVLE AHRDIVRFLV RLDDFRFASA GDDGIIVVWN AQTGEKLLEL RGHTQKITAV IAFPPLDSCE ASSQLLLTAS ADRTVGVWDC DTGRQIQRVT CFQSTVKCLT VLQRLDIWLS GGSDLGVWNR KLDLLCKTSH LSDTGISALV EIPGNCVAAA VGRELIIFRL VTPTEELPEW DIIEVKRLLD HQDNILSLAN INDTGFVTGS HVGELLIWDA LDWTVQACER TFWSPTAQLD AQQEIKLFQK QNDISINHFT CDEENIFAAV GRGLYVYNLQ LKRVIACQKT AHDSNILHID KLPNRQLISC SEDGAVRMWE VREKQQLAAE PVPTGFFNMW GFGRVNKQAS QPVKKQEENV TTCSLELIGD LIGHSSSVEM FLYFEDHGLV TCSADHLIIL WKNGERESGV RSLKLFQKLE ENGDLYPESP
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Non-catalytic component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. The C9orf72-SMCR8 complex promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation. The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity.
  • 亞細胞定位：
    Cytoplasm.
  • 數據庫鏈接：


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