在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse WD repeat and FYVE domain-containing protein 3 (Wdfy3), partial

  • 中文名稱:
    小鼠Wdfy3重組蛋白
  • 貨號:
    CSB-YP754433MO
  • 說明書:
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Wdfy3重組蛋白
  • 貨號:
    CSB-EP754433MO
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Wdfy3重組蛋白
  • 貨號:
    CSB-EP754433MO-B
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Wdfy3重組蛋白
  • 貨號:
    CSB-BP754433MO
  • 說明書:
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Wdfy3重組蛋白
  • 貨號:
    CSB-MP754433MO
  • 說明書:
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Wdfy3
  • Uniprot No.:
  • 別名:
    Wdfy3; WD repeat and FYVE domain-containing protein 3; Beach domain; WD repeat and FYVE domain-containing protein 1; BWF1
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Required for selective macroautophagy (aggrephagy). Acts as an adapter protein by linking specific proteins destined for degradation to the core autophagic machinery members, such as the ATG5-ATG12-ATG16L E3-like ligase, SQSTM1 and LC3. Involved in the formation and autophagic degradation of cytoplasmic ubiquitin-containing inclusions (p62 bodies, ALIS/aggresome-like induced structures). Important for normal brain development. Essential for the formation of axonal tracts throughout the brain and spinal cord, including the formation of the major forebrain commissures. Involved in the ability of neural cells to respond to guidance cues. Required for cortical neurons to respond to the trophic effects of netrin-1/NTN1. Regulates Wnt signaling through the removal of DVL3 aggregates, likely in an autophagy-dependent manner. This process may be important for the determination of brain size during embryonic development. May regulate osteoclastogenesis by acting on the TNFSF11/RANKL - TRAF6 pathway. After cytokinetic abscission, involved in midbody remnant degradation. In vitro strongly binds to phosphatidylinositol 3-phosphate (PtdIns3P).
  • 基因功能參考文獻:
    1. Data provide a novel association between WDFY3 and the RANKL-induced osteoclastogenesis pathway via the modulation of TRAF6. PMID: 27330028
    2. The authors report that this evolutionarily conserved protein is required for the formation of axonal tracts throughout the brain and spinal cord, including the formation of the major forebrain commissures. PMID: 27648578
    3. Alfy translocalization likely is involved in the pathogenesis of amyotrophic lateral sclerosis. PMID: 25385288
    4. Wdfy3 is important in regulating neural progenitor divisions, neural migration, cerebral expansion and functional organization in the developing brain. Loss-of-function leads to pathological changes characteristic of autism spectrum disorders. PMID: 25198012
    5. gene expression profiling; in situ hybridization analysis revealed that the expressed BWF1 mRNA was restricted to the marginal region both in E14 and E16 embryonic brain, but became diffuse after birth PMID: 15342963

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus. Cytoplasm, cytosol. Nucleus, PML body. Membrane; Peripheral membrane protein; Cytoplasmic side. Perikaryon. Cell projection, axon.
  • 組織特異性:
    Widely expressed, with high levels in the brain (at protein level). In the brain, expressed by both neuronal and non-neuronal cells. Expressed in bones, in the periosteum, cartilage, growth plate, trabeculae of the primary spongiosa, and scattered hematop
  • 數據庫鏈接:


主站蜘蛛池模板: 大香线蕉伊人精品超碰| 天天做日日做天天添天天欢公交车| 老色鬼永久精品网站| 激情综合婷婷丁香五月| 亚洲一区 日韩精品 中文字幕| 亚洲熟女精品中文字幕| 亚洲日韩色在线影院性色| 婷婷网色偷偷亚洲男人甘肃| 欧美伊人久久大香线蕉综合| 国产-第1页-浮力影院| 中文无码伦av中文字幕在线| 亚洲精品无码ma在线观看| 亚洲精品国产suv| 99精品国产再热久久无毒不卡 | 亚洲丁香五月激情综合| 新香蕉少妇视频网站| 亚洲日韩中文字幕无码一区| 色悠久久久久综合网香蕉| 久久精品亚洲国产av老鸭网| 国产成人无码a区在线观看视频免费| 欧美老妇人与禽交| 欧美激情一区二区三区高清视频 | 一本一本久久a久久精品综合麻豆 三级男人添奶爽爽爽视频 | 丰满大肥婆肥奶大屁股| 无遮挡裸体免费视频尤物| 娇小萝被两个黑人用半米长| 精品亚洲成a人在线观看青青| 国产成人一区二区青青草原| 国产在线国偷精品产拍| 无码任你躁久久久久久老妇| 亚洲精品国产综合久久一线| 欧美人与动性行为视频| 久久精品www人人爽人人| 日本高清视频www夜色资源| 久久视频这里只有精品在线观看| 欧美真人性做爰一二区| 国精产品一二三区传媒公司| 无码专区亚洲综合另类| 久久www免费人成看片入口| 国产精品久线在线观看| 亚洲aⅴ无码专区在线观看|