在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse WAS/WASL-interacting protein family member 1 (Wipf1)

Recombinant Mouse WAS/WASL-interacting protein family member 1 (Wipf1)

  • 中文名稱：
    小鼠Wipf1重組蛋白
  • 貨號：
    CSB-YP812968MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Wipf1重組蛋白
  • 貨號：
    CSB-EP812968MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Wipf1重組蛋白
  • 貨號：
    CSB-EP812968MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Wipf1重組蛋白
  • 貨號：
    CSB-BP812968MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Wipf1重組蛋白
  • 貨號：
    CSB-MP812968MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Wipf1; Waspip; Wip; WAS/WASL-interacting protein family member 1; Wiskott-Aldrich syndrome protein-interacting protein; WASP-interacting protein
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-493
  • 氨基酸序列
    MPVPPPPAPP PPPTFALANT EKPTLNKTEQ AGRNALLSDI SKGKKLKKTV TNDRSAPILD KPKGAGASAG GYGGGGGGGG GGGGGGGGSG GNFGGGGPPG LGGLFQAGMP KLRSTANRDN DSGGSRPPIL PPGGRATSAK PFSPPSGPGR FPAPSPGHRS GPPEPPRNRM PPPRPDVGSK PDSLPPPVPN TPRPVPSSLH NRGSPAGLGA PRPPFPGNRG AAFGAGSARQ NPSGSSSPFP RPPLPPTPSR ALDDKPPPPP PPVGNRPSMH REAVPPPPSQ TSKPPVPSTP RPGLGSQAPP PPPPPSRPGP PPLPPASNDE IPRLPQRNLS LTSSAPPLPS PGRSGPLPPP PSERPPPPVR DPPGRSGPLP PPPPINRNGS TARALPATPQ LPSRSGMDSP RSGPRPPLPP DRPGAGAPPP PPPSTSVRNG FQDSSCEDEW ESRFYFHPIS DLPPPEPYVP TTKTYPSKLA RNESRSGSNR RERGAPPLPP IPR
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays a role in the reorganization of the actin cytoskeleton. Contributes with NCK1 and GRB2 in the recruitment and activation of WASL. May participate in regulating the subcellular localization of WASL, resulting in the disassembly of stress fibers in favor of filopodia formation. Plays a role in the formation of cell ruffles.
  • 基因功能參考文獻：
    1. These experiments identify WIP as a member of a signaling cascade comprised of Abl family kinases, mTORC1 and S6K, which regulates neuron development and specifically, neuritic branching and complexity. PMID: 26664784
    2. WIP is a link between membrane lipid composition and actin cytoskeleton at dendritic spines. PMID: 24698977
    3. WIPf1 deficiency results in defective B cell function. By regulating the cortical actin cytoskeleton, WIPf1 influences the function of CD19 as a general hub for PI3K signaling. PMID: 26453379
    4. WIP binding to actin, independently of its binding to Wiskott-Aldrich syndrome protein, is critical for the integrity of the actin cytoskeleton in T cells and for their migration into tissues. PMID: 25246631
    5. Results show that WIP is a novel regulator of focal adhesion assembly and cell adhesion. PMID: 24797074
    6. Data indicate the involvement of WIP (WASP Interacting Protein) in the control of migratory persistence in both mesenchymal (fibroblast) and amoeboid (B lymphocytes) motility. PMID: 23950925
    7. This study implicates WIP in enteropathogenic Escherichia coli-mediated actin polymerization and pedestal elongation. PMID: 22372637
    8. These findings identify a novel role for mAbp1 in growth factor-induced dorsal ruffle formation through its interaction with WIP. PMID: 19910490
    9. WIP participates in the actin reorganization that leads to ruffle formation. PMID: 12724353
    10. WIP regulates FcepsilonRI-mediated mast cell activation by regulating Syk levels and actin cytoskeleton rearrangement. PMID: 14757742
    11. results suggest that WASP and WIP are not essential for T lymphocyte rolling and adhesion, but play important and partially redundant roles in T cell chemotaxis in vitro and homing in vivo and function downstream of small GTPases PMID: 16141245
    12. WIP acts as a negative regulator of fibroblast migration. PMID: 17008118
    13. WASP-interacting protein stabilizes Wiskott-Aldrich syndrome protein(WASP) and suggest that it may also be important for its function PMID: 17213309
    14. These results indicate that WIP is essential for IL-2 signaling and responsiveness in T cells, possibly because of its critical role in TCR-triggered actin cytoskeletal reorganization. PMID: 19359486
    15. platelet-associated IgAs negatively modulate glycoprotein VI signaling and function in Wiskott-Aldrich syndrome protein-interacting protein KO mice. PMID: 19692704

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasmic vesicle. Cytoplasm, cytoskeleton. Cell projection, ruffle.
  • 蛋白家族：
    Verprolin family
  • 數據庫鏈接：


主站蜘蛛池模板： 大肉大捧一进一出视频| 亚洲精品久久久久久中文传媒| 情侣作爱视频网站| 国产精品无码mv在线观看| 欧美性狂猛xxxxx深喉| 越南女子杂交内射bbwxz| 人妻无码中文字幕永久在线| 久久久久成人片免费观看蜜芽| 国产一三四2021不卡| 四虎成人精品在永久在线| 高清国产亚洲欧洲av综合一区| 天堂网在线观看| 成人片黄网站a毛片免费| 久久精品无码免费不卡| 国产亚洲精品久久久久久彩霞| 国产成人无码一区二区三区| 亚洲日韩精品a∨片无码加勒比| 西西人体大胆4444www| 亚洲欧洲免费三级网站| av制服丝袜白丝国产网站| 国产黄大片在线观看画质优化| 欧美亅性猛交内射| 免费国产精品视频在线| 天堂资源中文| 丰满熟妇人妻中文字幕 | 欧美丰满熟妇xx猛交| 欧洲-级毛片内射| 久久俺也去丁香综合色| 暴力调教一区二区三区| 97精品一区二区视频在线观看 | 法国白嫩大屁股xxxx| 日韩爆乳一区二区无码| 18禁超污无遮挡无码免费动态图| 欧美激情在线播放| 国产又黄又爽又色的免费| 7777奇米成人狠狠成人影视| 日本熟妇浓毛| 亚洲欧美韩国综合色| 国产中的精品av一区二区| 同性男男黄g片免费网站| 真实国产乱子伦对白视频不卡|