在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Voltage-dependent anion-selective channel protein 2 (Vdac2), partial

Recombinant Mouse Voltage-dependent anion-selective channel protein 2 (Vdac2), partial

  • 中文名稱：
    小鼠Vdac2重組蛋白
  • 貨號：
    CSB-YP723359MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Vdac2重組蛋白
  • 貨號：
    CSB-EP723359MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Vdac2重組蛋白
  • 貨號：
    CSB-EP723359MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Vdac2重組蛋白
  • 貨號：
    CSB-BP723359MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Vdac2重組蛋白
  • 貨號：
    CSB-MP723359MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Vdac2; Vdac6; Voltage-dependent anion-selective channel protein 2; VDAC-2; mVDAC2; Outer mitochondrial membrane protein porin 2; Voltage-dependent anion-selective channel protein 6; VDAC-6; mVDAC6
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. Binds various lipids, including the sphingolipid ceramide, the phospholipid phosphatidylcholine, and the sterol cholesterol. Binding of ceramide promotes the Binding of ceramide promotes the mitochondrial outer membrane permeabilization (MOMP) apoptotic pathway.
  • 基因功能參考文獻：
    1. an important MYBL2-VDAC2-BECN1-BCL2L1 pathway linking autophagy suppression in the developing ovary, is reported. PMID: 26060891
    2. Motifs of VDAC2 required for mitochondrial Bak import and tBid-induced apoptosis. PMID: 26417093
    3. Bax localizes to the mitochondrial outer membrane via alternate mechanisms, either constitutively via an interaction with VDAC2 or after activation via interaction with Bcl-2 family proteins. PMID: 25146925
    4. Bcl-xL interacts functionally with VDAC1 and -3 but not VDAC2. PMID: 23720737
    5. Abnormal regulation of VDACs negatively affected sperm function. Thus, VDACs may be key regulators of the fertilization ability of spermatozoa. PMID: 23062735
    6. VDAC2 acts as a crucial component in mitochondrial apoptosis by allowing the mitochondrial recruitment of BAK, thereby controlling tBID-induced OMM permeabilization and cell death. PMID: 19820692
    7. VDAC2 regulates the activity of BAK and provides a connection between mitochondrial physiology and the core apoptotic pathway PMID: 12881569
    8. Genetic depletion of Vdac2 in the thymus resulted in excessive cell death & hypersensitivity to diverse death stimuli including engagement of the T cell receptor. The VDAC2-BAK axis governs the homeostasis of thymocytes. PMID: 19706873

    顯示更多

    收起更多

  • 亞細胞定位：
    Mitochondrion outer membrane. Membrane.
  • 蛋白家族：
    Eukaryotic mitochondrial porin family
  • 組織特異性：
    Highest levels of expression detected in testis, less but still abundant expression in heart, kidney, brain, and skeletal muscle.
  • 數據庫鏈接：


主站蜘蛛池模板： 麻豆国产人妻欲求不满| 欧美日韩午夜群交多人轮换| 激情综合色五月丁香六月欧美| 欧洲美熟女乱又伦| 国产色xx群视频射精| 中文人妻无码一区二区三区| 在线天堂中文www官网| 久久久久久无码日韩欧美| 无人区一线二线三线乱码| 波多野结衣乳巨码无在线| 久久精品国产99国产精品| 一出一进一爽一粗一大视频| 国产精品欧美福利久久| 十八禁啪啪无遮挡网站| 日本熟妇厨房bbw| 宅女午夜福利免费视频| 女人被狂躁c到高潮视频| 男女车车的车车网站w98免费| 九九影院午夜理论片少妇| 影音先锋日日狠狠久久| 国产台湾无码av片在线观看| а天堂中文最新一区二区三区| 99久热re在线精品99 6热视频| 国产麻豆md传媒视频| 久久亚洲精品国产精品777777| 毛片完整版的免费观看| 久久国产超碰女女av| 国产69精品久久久久人妻| 久久人人爽人人爽人人片av麻烦| 亚洲国产精品一区第二页| 中文字幕乱码久久午夜不卡| 亚洲综合成人av一区在线观看| 国产在线精品一区二区中文| 77777亚洲午夜久久多人| 伊人色综合久久天天网| 欧美欧洲成本大片免费| 中国女人做爰视频| 曰韩少妇内射免费播放| 蜜芽av无码精品国产午夜| 国产电影一区二区三区| 日本大片免a费观看视频三区|