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  4. Recombinant Mouse Uncharacterized protein KIAA2022 (Kiaa2022), partial

Recombinant Mouse Uncharacterized protein KIAA2022 (Kiaa2022), partial

  • 中文名稱：
    小鼠Nexmif重組蛋白
  • 貨號：
    CSB-YP682609MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Nexmif重組蛋白
  • 貨號：
    CSB-EP682609MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Nexmif重組蛋白
  • 貨號：
    CSB-EP682609MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Nexmif重組蛋白
  • 貨號：
    CSB-BP682609MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Nexmif重組蛋白
  • 貨號：
    CSB-MP682609MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Nexmif
  • Uniprot No.：
  • 別名：
    Nexmif; Kiaa2022; Neurite extension and migration factor; KIAA2022 protein associated with intellectual disability; language impairment and autistic behavior homolog; KIDLIA
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Involved in neurite outgrowth by regulating cell-cell adhesion via the N-cadherin signaling pathway. May act by regulating expression of protein-coding genes, such as N-cadherins and integrin beta-1 (ITGB1).
  • 基因功能參考文獻：
    1. Knockdown of KIAA2022/KIDLIA leads to altered neuron migration and a reduction in dendritic growth and disorganized apical dendrite projections in layer II/III cortical neurons. In cultured neurons loss of KIDLIA expression also leads to suppression of dendritic growth and branching. KIDLIA suppression leads to an increase in cell-surface N-cadherin and an elevated association of N-cadherin with delta-catenin. PMID: 27822498
  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 組織特異性：
    Expressed in the brain, particularly during the late embryonic and perinatal stages of development. In the developing brain, it is expressed only in the cortical plate and subplate region but not in the intermediate or ventricular zone.
  • 數據庫鏈接：


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