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Recombinant Mouse Uncharacterized protein KIAA0226-like (Kiaa0226l)

  • 中文名稱:
    小鼠Rubcnl重組蛋白
  • 貨號(hào):
    CSB-YP668836MO
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Rubcnl重組蛋白
  • 貨號(hào):
    CSB-EP668836MO
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Rubcnl重組蛋白
  • 貨號(hào):
    CSB-EP668836MO-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Rubcnl重組蛋白
  • 貨號(hào):
    CSB-BP668836MO
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Rubcnl重組蛋白
  • 貨號(hào):
    CSB-MP668836MO
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Rubcnl
  • Uniprot No.:
  • 別名:
    RubcnlProtein associated with UVRAG as autophagy enhancer; Pacer; Protein Rubicon-like
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達(dá)區(qū)域:
    1-648
  • 氨基酸序列
    MVSQSIGWGD SPVDLCEGSN RAFQDTDQPA CQLDVRLLRH KASWINPLCV QQPLQELCPQ RPTVQSSENH VVLDTPSPLR LSILSYRDSL AEMPLSENTA DVICSNSAHC SGGKEGDFFL ATEEQEVHLQ QESLLKNPKT VATSPSPKEG SARSESPHLT ASTDDGDARS SSRSHAWNFF PLETFMLPAD VEKENLHFYA ADIIISVIEN MKCNLPNQQQ PERWDTEDAS RLRGTGAEMT FYTHIKQEPG SSASSHTGCE GCAALQVSPV AETLSYCPVA GEACKHDLNK LVMLELGKYN DITKGCRCSY NSSKSATCES NLSPAGCLAR ELFRGFCKCW MLSEVNCQLP GSPTTASSGV GDEEYAEEDF DSSVDAAREV MLKSRVPGTE DWVLPRCQII LTVHPPIKRD IAVVAQNFFC AGCGTPIQPK FVKRLRYCEY LGKYFCASCH SSAESCIPAR ILTMWDFRKY QVSDFSKWLL DSVWHQPVFK LLGGHHSLYA KAKELDRVKD LQEQLFHIKK LLKTCRFADS VLKEFEQVPS HLTDECHIFS MDDFLRTKKG LLAPLLKDIL RASLAHVDSC ELCQGKGFIC EFCQSTTVIF PFQTTTCRRC AACRACFHKQ CFQSSRCPRC ARIIARRQHL ESLPTAAT
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Regulator of autophagy that promotes autophagosome maturation by facilitating the biogenesis of phosphatidylinositol 3-phosphate (PtdIns(3)P) in late steps of autophagy. Acts by antagonizing RUBCN, thereby stimulating phosphatidylinositol 3-kinase activity of the PI3K/PI3KC3 complex. Following anchorage to the autophagosomal SNARE STX17, promotes the recruitment of PI3K/PI3KC3 and HOPS complexes to the autophagosome to regulate the fusion specificity of autophagosomes with late endosomes/lysosomes. Binds phosphoinositides phosphatidylinositol 3-phosphate (PtdIns(3)P), 4-phosphate (PtdIns(4)P) and 5-phosphate (PtdIns(5)P). In addition to its role in autophagy, acts as a regulator of lipid and glycogen homeostasis. May act as a tumor suppressor.
  • 亞細(xì)胞定位:
    Cytoplasmic vesicle, autophagosome membrane; Peripheral membrane protein.
  • 數(shù)據(jù)庫鏈接:


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