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  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Uncharacterized protein C20orf72 homolog

Recombinant Mouse Uncharacterized protein C20orf72 homolog

  • 中文名稱(chēng)：
    小鼠Mgme1重組蛋白
  • 貨號(hào)：
    CSB-YP861482MO
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱(chēng)：
    小鼠Mgme1重組蛋白
  • 貨號(hào)：
    CSB-EP861482MO
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱(chēng)：
    小鼠Mgme1重組蛋白
  • 貨號(hào)：
    CSB-EP861482MO-B
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱(chēng)：
    小鼠Mgme1重組蛋白
  • 貨號(hào)：
    CSB-BP861482MO
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱(chēng)：
    小鼠Mgme1重組蛋白
  • 貨號(hào)：
    CSB-MP861482MO
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Mgme1
  • Uniprot No.：
  • 別名：
    Mgme1; Mitochondrial genome maintenance exonuclease 1; EC 3.1.-.-
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    65-338
  • 氨基酸序列
    TPESLF KEDDVLYGPV SKHKAAEPEP QARVPQHCFP IFNEERTGKP HTDASSSPLK IPLQRNSIPS VTRILQQTMP PEQSFFLERW KERMVLELGE DGFAEYTSNV FLQGKQFHKA LESILSPQEN LTGGEEHPQC GYIESIQHIL TEISGVQALE SAVQHEALKY VGLLDCVAEY RGKLCVIDWK TSEKPKPLIR NTYDNPLQVV AYMGAVNHDA HYSFQVQCGL IVVAYKDGSP AHPHFMDEEL CSKYWAKWLL RLEEYTEKQK NLSAPEPA
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.
  • 基因功能參考文獻(xiàn)：
    1. MGME1 is part of a termination complex acting at the end of the D-loop region where it modulates mtDNA replication and H-strand transcription termination. Mice with MGME1 deficiency accumulate a long linear subgenomic mtDNA species, but do not develop progeria. PMID: 29572490
  • 亞細(xì)胞定位：
    Mitochondrion.
  • 蛋白家族：
    MGME1 family
  • 數(shù)據(jù)庫(kù)鏈接：


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