在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Ubiquitin-conjugating enzyme E2 variant 1 (Ube2v1)

Recombinant Mouse Ubiquitin-conjugating enzyme E2 variant 1 (Ube2v1)

  • 中文名稱：
    小鼠Ube2v1重組蛋白
  • 貨號：
    CSB-YP025482MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Ube2v1重組蛋白
  • 貨號：
    CSB-EP025482MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Ube2v1重組蛋白
  • 貨號：
    CSB-EP025482MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Ube2v1重組蛋白
  • 貨號：
    CSB-BP025482MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Ube2v1重組蛋白
  • 貨號：
    CSB-MP025482MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Ube2v1
  • Uniprot No.：
  • 別名：
    Ube2v1; Croc1; Ubiquitin-conjugating enzyme E2 variant 1; UEV-1; CROC-1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-147
  • 氨基酸序列
    AATTGSGVK VPRNFRLLEE LEEGQKGVGD GTVSWGLEDD EDMTLTRWTG MIIGPPRTIY ENRIYSLKIE CGPKYPEAPP SVRFVTRVNM SGVSSSNGVV DPRATAVLAK WQNSHSIKVI LQELRRLMMS KENMKLPQPP EGQCYSN
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Has no ubiquitin ligase activity on its own. The UBE2V1-UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination activates IKK and does not seem to involve protein degradation by the proteasome. Plays a role in the activation of NF-kappa-B mediated by IL1B, TNF, TRAF6 and TRAF2. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. Promotes TRIM5 capsid-specific restriction activity and the UBE2V1-UBE2N heterodimer acts in concert with TRIM5 to generate 'Lys-63'-linked polyubiquitin chains which activate the MAP3K7/TAK1 complex which in turn results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes. Together with RNF135 and UBE2N, catalyzes the viral RNA-dependent 'Lys-63'-linked polyubiquitination of RIG-I/DDX58 to activate the downstream signaling pathway that leads to interferon beta production. UBE2V1-UBE2N together with TRAF3IP2 E3 ubiquitin ligase mediate 'Lys-63'-linked polyubiquitination of TRAF6, a component of IL17A-mediated signaling pathway.
  • 基因功能參考文獻：
    1. modification of proteins with Lys(63)-linked ubiquitin chains occurs through a UEV1A-independent substrate modification and UEV1A-dependent Lys(63)-linked ubiquitin chain synthesis mechanism PMID: 17709375
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Ubiquitin-conjugating enzyme family
  • 組織特異性：
    Ubiquitous. Highly expressed in heart, brain, liver, skeletal msucle, kidney and testis. Detected at lower levels in lung and spleen.
  • 數據庫鏈接：


主站蜘蛛池模板： 英语老师丝袜娇喘好爽视频| 亚洲αv无码一区二区三区四区 | 激情 小说 亚洲 图片 伦| 又黄又爽又猛的视频免费| 精品亚洲欧美自拍| 国产亚洲曝欧美曝妖精品| 中文字幕亚洲欧美在线不卡| 99草草国产熟女视频在线| 中年人妻丰满av无码久久不卡| 236宅宅理论片免费| 国产色视频自在线观看| 国产成人av无码永久免费一线天| aⅴ亚洲 日韩 色 图网站 播放| 国产精品高清一区二区三区| 免费人成视频在线观看视频| 在线成人a毛片免费播放| 波多野无码黑人在线播放| 国产乱妇无码大片在线观看| 国产9色在线 | 日韩| 又色又污又爽又黄的网站| 午夜性色吃奶添下面69影院| 国产乱了伦视频大全亚琴影院| 日出水了特别黄的视频| 呦男呦女视频精品八区| 少妇无码av无码一区| 熟女肥臀白浆大屁股一区二区| 国产肉体ⅹxxx137大胆| 白丝乳交内射一二三区| 亚洲一二区制服无码中字| 亚洲熟妇中文字幕五十中出| 色先锋av影音先锋在线| 日本妇人成熟免费视频| 精品无码国产自产在线观看水浒传| 欧美疯狂做受xxxx高潮| 中文人妻av久久人妻18| 国产精品久久久久久tv| 永久免费无码av网站在线观看| 国产又粗又猛又大爽老大爷| 99久久免费国产精品| 黑色丝袜无码中中文字幕| 无码国产伦一区二区三区视频|