在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Ubiquitin-conjugating enzyme E2 B (Ube2b)

Recombinant Mouse Ubiquitin-conjugating enzyme E2 B (Ube2b)

  • 中文名稱：
    小鼠Ube2b重組蛋白
  • 貨號：
    CSB-YP025439MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Ube2b重組蛋白
  • 貨號：
    CSB-EP025439MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Ube2b重組蛋白
  • 貨號：
    CSB-EP025439MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Ube2b重組蛋白
  • 貨號：
    CSB-BP025439MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Ube2b重組蛋白
  • 貨號：
    CSB-MP025439MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Ube2b; Rad6b; Ubiquitin-conjugating enzyme E2 B; EC 2.3.2.23; E2 ubiquitin-conjugating enzyme B; E214K; RAD6 homolog B; HR6B; mHR6B; Ubiquitin carrier protein B; Ubiquitin-protein ligase B
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達(dá)區(qū)域：
    1-152
  • 氨基酸序列
    MSTPARRRLM RDFKRLQEDP PVGVSGAPSE NNIMQWNAVI FGPEGTPFED GTFKLVIEFS EEYPNKPPTV RFLSKMFHPN VYADGSICLD ILQNRWSPTY DVSSILTSIQ SLLDEPNPNS PANSQAAQLY QENKREYEKR VSAIVEQSWN DS
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11'-, as well as 'Lys-48'- and 'Lys-63'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA. Associates to the E3 ligase RAD18 to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. May be involved in neurite outgrowth.
  • 基因功能參考文獻(xiàn)：
    1. These results suggest that Ube2b, as a direct androgen receptor transcriptional target in Sertoli cells, mediates the function of androgen recpetor in spermatogenesis by promoting H2A ubiquitylation. PMID: 23863405
    2. HR6B represses major satellite repeat transcription in spermatocytes, and functions in the maintenance of X chromosome silencing in spermatocytes and spermatids. PMID: 20537150
    3. The present findings reveal a specific requirement for the ubiquitin-conjugating activity of HR6B in relation to dynamic aspects of the synaptonemal complex and meiotic recombination in spermatocytes. PMID: 12556476
    4. Ube2b deficient mice are shown to present male infertility and sperm head shape anomalies. PMID: 12784252
    5. HR6B exerts control over different histone modifications in spermatocytes and spermatids, and that this function contributes to the postmeiotic maintenance of X chromosome silencing. PMID: 17488778

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane. Nucleus.
  • 蛋白家族：
    Ubiquitin-conjugating enzyme family
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 欧美成年网站色a| 国产精品成人国产乱| (无码视频)在线观看| 又爽又黄无遮拦成人网站| 日韩国产高清一区二区| av无码一区二区二三区1区6区| 人人莫人人擦人人看| 成人丝袜激情一区二区| 97久久超碰亚洲视觉盛宴| 国产无遮挡又爽又刺激的视频老师| 中文天堂最新版在线www | 熟女毛多熟妇人妻在线视频| 97久久超碰精品视觉盛宴| 亚洲图片小说激情综合| 日本黄页网站免费大全| 国产手机在线αⅴ片无码观看| 久久久精品2020免费观看| 天天狠天天透天干天天| 久爱无码免费视频在线| 精品人妻午夜一区二区三区四区| 欧美破苞系列二十三| 青青草无码伊人久久| 中文字字幕乱码视频高清 | 少妇无码一区二区三区免费| 吃奶呻吟打开双腿做受动态图| 羞羞色男人的天堂| 久久精品国产欧美日韩99热| 欧美性色老妇人| 一区二区三区国产| 人妻少妇69式99偷拍| 女女同性av片在线观看免费 | 美女大量吞精在线观看456| 狠狠干狠狠爱| av无码人妻无码男人的天堂| 成人爽a毛片在线视频淮北| 免费无码又爽又刺激聊天app| 亚洲免费观看在线视频| 97超碰精品成人国产| 国产欧美丝袜在线二区| 无码人妻一区二区三区在线| 亚洲精品久久久www|