Recombinant Mouse U1 small nuclear ribonucleoprotein C (Snrpc)

中文名稱：

小鼠Snrpc重組蛋白
貨號：

CSB-YP720293MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Snrpc重組蛋白
貨號：

CSB-EP720293MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Snrpc重組蛋白
貨號：

CSB-EP720293MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Snrpc重組蛋白
貨號：

CSB-BP720293MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Snrpc重組蛋白
貨號：

CSB-MP720293MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Snrpc
Uniprot No.：

Q62241
別名：

Snrpc; Snrp1c; U1 small nuclear ribonucleoprotein C; U1 snRNP C; U1-C; U1C
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-159
氨基酸序列

MPKFYCDYCD TYLTHDSPSV RKTHCSGRKH KENVKDYYQK WMEEQAQSLI DKTTAAFQQG KIPPAPFSAP PPAGAMIPPP PSLPGPPRPG MMPAPHMGGP PMMPMMGPPP PGMMPVGPAP GMRPPMGGHM PMMPGPPMMR PPARPMMVPT RPGMTRPDR
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
基因功能參考文獻：
1. these studies establish potentially converging disease mechanisms in amyotrophic lateral sclerosis (ALS) and spinal muscular atrophy, with ALS-causative mutants acquiring properties representing both gain and loss of function. PMID: 25625564
亞細胞定位：

Nucleus.
蛋白家族：

U1 small nuclear ribonucleoprotein C family
組織特異性：

Widely expressed. In the testis, expressed in somatic and germinal testicular cells but not in elongated spermatids.
數據庫鏈接：

KEGG: mmu:20630

STRING: 10090.ENSMUSP00000063976

UniGene: Mm.103949