Recombinant Mouse Tyrosine-protein phosphatase non-receptor type 7 (Ptpn7)

中文名稱：

小鼠Ptpn7重組蛋白
貨號(hào)：

CSB-YP805341MO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Ptpn7重組蛋白
貨號(hào)：

CSB-EP805341MO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Ptpn7重組蛋白
貨號(hào)：

CSB-EP805341MO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Ptpn7重組蛋白
貨號(hào)：

CSB-BP805341MO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Ptpn7重組蛋白
貨號(hào)：

CSB-MP805341MO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Ptpn7
Uniprot No.：

Q8BUM3
別名：

Ptpn7; Tyrosine-protein phosphatase non-receptor type 7; EC 3.1.3.48; Hematopoietic protein-tyrosine phosphatase; HEPTP
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達(dá)區(qū)域：

1-359
氨基酸序列

MVQACEGRSR AQLPTLSLGA DMTQPPPTKA PAKKHVRLQE RRGSSVALML DVQSLGTVEP ICSVNTPREV TLHFLRTAGH PLTRWTLQHQ PPSPKQLEEE FLKIPSNFVN PEDLDIPGHA SKDRYKTILP NPQSRVCLGR AQSQEDSDYI NANYIRGYDG KEKVYIATQG PMPNTVADFW EMVWQEDVSL IVMLTQLREG KEKCVHYWPT EEEAYGPFQI RIQDMKEHPE YTVRQLTIQH QQECRSVKHI LFSAWPDHQT PESAGPLLRL VAEVETPETA ANSGPIVVHC SAGIGRTGCF IATRIGCQQL KARGEVDILG IVCQLRLDRG GMIQTAEQYQ FLHHTLALYA AQLPPEPNP
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

May play a role in the regulation of T and B-lymphocyte development and signal transduction.
基因功能參考文獻(xiàn)：
1. PTPN7 as a negative regulator of TNF-alpha expression and the inflammatory response in macrophages PMID: 24265715
2. beta(2)AR stimulation on a B cell phosphorylates and inactivates HePTP in a Gs/cAMP/PKA-dependent manner to release bound p38 MAPK, making more available for phosphorylation and subsequent IgE regulation. PMID: 19047375
亞細(xì)胞定位：

Cytoplasm. Cytoplasm, cytoskeleton. Note=Oxidized form is preferentially associated with actin cytoskeleton.
蛋白家族：

Protein-tyrosine phosphatase family, Non-receptor class subfamily
組織特異性：

Expressed in bone marrow-derived mast cells.
數(shù)據(jù)庫鏈接：

KEGG: mmu:320139

STRING: 10090.ENSMUSP00000045803

UniGene: Mm.258388