在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Tubulin polymerization-promoting protein (Tppp)

  • 中文名稱:
    小鼠Tppp重組蛋白
  • 貨號:
    CSB-YP766513MO
  • 說明書:
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Tppp重組蛋白
  • 貨號:
    CSB-EP766513MO
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Tppp重組蛋白
  • 貨號:
    CSB-EP766513MO-B
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Tppp重組蛋白
  • 貨號:
    CSB-BP766513MO
  • 說明書:
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Tppp重組蛋白
  • 貨號:
    CSB-MP766513MO
  • 說明書:
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Tppp
  • Uniprot No.:
  • 別名:
    Tppp; Tubulin polymerization-promoting protein; TPPP; EC 3.6.5.-; 25 kDa brain-specific protein; TPPP/p25; p25-alpha
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-218
  • 氨基酸序列
    MADSKAKPAK AANKTPPKSP GDPARAAKRL SLESEGANEG ATAAPELSAL EEAFRRFAVH GDTRATGKEM HGKNWSKLCK DCHVIDGKNV TVTDVDIVFS KIKGKSCRTI TFEQFQEALE ELAKKRFKDK SSEEAVREVH RLIEGRAPVI SGVTKAVSSP TVSRLTDTSK FTGSHKERFD QSGKGKGKAG RVDLVDESGY VPGYKHAGTY DQKVQGGK
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Regulator of microtubule dynamics that plays a key role in myelination by promoting elongation of the myelin sheath. Acts as a microtubule nucleation factor in oligodendrocytes: specifically localizes to the postsynaptic Golgi apparatus region, also named Golgi outpost, and promotes microtubule nucleation, an important step for elongation of the myelin sheath. Required for both uniform polarized growth of distal microtubules as well as directing the branching of proximal processes. Shows magnesium-dependent GTPase activity; the role of the GTPase activity is unclear. In addition to microtubule nucleation activity, also involved in microtubule bundling and stabilization of existing microtubules, thereby maintaining the integrity of the microtubule network. Regulates microtubule dynamics by promoting tubulin acetylation: acts by inhibiting the tubulin deacetylase activity of HDAC6. Also regulates cell migration: phosphorylation by ROCK1 inhibits interaction with HDAC6, resulting in decreased acetylation of tubulin and increased cell motility. Plays a role in cell proliferation by regulating the G1/S-phase transition. Involved in astral microtubule organization and mitotic spindle orientation during early stage of mitosis; this process is regulated by phosphorylation by LIMK2.
  • 基因功能參考文獻:
    1. The present study provides additional support for roles for TPPP in the etiology of depression following early adversity. PMID: 27506655
    2. These results support an essential role for TPPP/p25 in oligodendrocyte differentiation likely via rearrangement of the microtubule system during the process elongation prior to the onset of myelination. PMID: 19606501
    3. LIMK1 phosphorylation of p25 blocks p25 activity, thus promoting microtubule disassembly. PMID: 18028908
    4. A pathway was discovered by which p25 and cdk5 increases the amyloidogenic processing of amyloid precursor protein. PMID: 18341989
  • 亞細胞定位:
    Golgi outpost. Cytoplasm, cytoskeleton, microtubule organizing center. Cytoplasm, cytoskeleton. Nucleus. Cytoplasm, cytoskeleton, spindle.
  • 蛋白家族:
    TPPP family
  • 組織特異性:
    Widely expressed with higher expression in brain (at protein level).
  • 數據庫鏈接:


主站蜘蛛池模板: 最新亚洲一卡二卡三卡四卡| 国产av无码专区影视| 中文字幕制服丝袜人妻动态图| 欧美人与动牲交aⅴ| 试看120分钟做受小视频| 国产成人精品无码片区在线观看| 99久久久无码国产精品古装| 中文无码高潮到痉挛在线视频| 在线播放十八禁视频无遮挡| 成人亚洲欧美日韩在线观看| 男女久久久国产一区二区三区| 久久日本片精品aaaaa国产| 久久久亚洲欧洲日产国码aⅴ| 97香蕉碰碰人妻国产欧美| 久久综合亚洲鲁鲁五月天| 日产日韩亚洲欧美综合在线| 亚洲精品久久久久国产剧8| 久久精品噜噜噜成人av| 亚洲午夜国产精品无码老牛影视| 免费国产a国产片高清| 无码av动漫精品一区二区免费| 伊人精品无码av一区二区三区| 精品国产天线2019| 免费国精产品—品二品| 国内精品视频自在一区| 久久精品人人槡人妻人人玩av| 亚洲色精品88色婷婷七月丁香| 欧美一区二区三区| 男女下面进入的视频| 国产成人亚洲高清一区| 国产a v高清一区二区三区| 久久无码专区国产精品| 国产精品无码免费播放| 国产精品美脚玉足脚交欧美| 国产精自产拍在线看中文| 国产无遮挡a片又黄又爽漫画 | 日韩av无码免费播放| 国产久热精品无码激情| 欧美黑人巨大videos在线| 国产69精品久久久久乱码韩国 | 国产精品乱码一区二区三区|