在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Tripartite motif-containing protein 30A (Trim30a)

  • 中文名稱:
    小鼠Trim30a重組蛋白
  • 貨號:
    CSB-YP325362MO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Trim30a重組蛋白
  • 貨號:
    CSB-EP325362MO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Trim30a重組蛋白
  • 貨號:
    CSB-EP325362MO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Trim30a重組蛋白
  • 貨號:
    CSB-BP325362MO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Trim30a重組蛋白
  • 貨號:
    CSB-MP325362MO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Trim30a
  • Uniprot No.:
  • 別名:
    Trim30a; Rpt-1; Rpt1; Trim30; Tripartite motif-containing protein 30A; Down regulatory protein of interleukin-2 receptor; Tripartite motif-containing protein 30
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達區域:
    1-496
  • 氨基酸序列
    MASSVLEMIK EEVTCPICLE LLKEPVSADC NHSFCRACIT LNYESNRNTD GKGNCPVCRV PYPFGNLRPN LHVANIVERL KGFKSIPEEE QKVNICAQHG EKLRLFCRKD MMVICWLCER SQEHRGHQTA LIEEVDQEYK EKLQGALWKL MKKAKICDEW QDDLQLQRVD WENQIQINVE NVQRQFKGLR DLLDSKENEE LQKLKKEKKE VMEKLEESEN ELEDQTELVR DLISDVEHHL ELSTLEMLQG ANCVLRRSQS LSLQQPQTVP QKRKRTFQAP DLKGMLQVYQ GLMDIQQYWV HMTLHARNNA VIAINKEKRQ IQYRSYNTVP VSEIYHLGVL GYPALSSGKH YWEVDISRSD AWLLGLNDGK CAQPQLHSKE EMGIKKNLHS QIKQNVLFQP KCGYWVIGMK NPSVYKAFDE CSITHNSSIL VISLPDRPSR VGVFLDRKAG TLSFYDVSNC GALIYRFYDP AFPVEVYPYF NPMKCSEPMT ICGPPS
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Trans-acting factor that regulates gene expression of interleukin 2 receptor alpha chain. May affect IL2R-alpha expression through cis-acting negative regulatory elements or through competition with proteins that bind to enhancer or activator sequences. Negatively regulates Toll-like receptor (TLR)-mediated activation of NFKB by promoting degradation of TAB2 and TAB3 and preventing TRAF6 autoubiquitination. Negatively regulates production of reactive oxygen species (ROS) which inhibits activation of the NLRP3 inflammasome complex. This, in turn, regulates activation of CASP1 and subsequent cleavage of IL1B and IL18. No activity detected against a range of retroviruses including a number of lentiviruses, gammaretroviruses and betaretroviruses.
  • 基因功能參考文獻:
    1. E3 ligase TRIM30alpha is an important negative-feedback regulator of innate immune responses to DNA viruses by targeting STING PMID: 26114947
    2. Data indicated that Trim30 and Ucp3 play pivotal roles in energy balance and glucose homeostasis and might be used as genetic markers to represent the stage of obesity during the early and late stages of adipose tissue development, respectively. PMID: 25895476
    3. These results indicate a distinct requirement for TRIM30 in modulation of NF-kappaB activation and cell proliferation induced by TCR stimulation. PMID: 24756037
    4. Lymphotoxin-beta receptor signalling regulates cytokine expression via TRIM30alpha in a TRAF3-dependent manner. PMID: 23220069
    5. TRIM30alpha is a target gene of LTbetaR signaling in bone marrow-derived macrophages LTbetaR-induced TRIM30alpha expression inhibits the production of proinflammatory cytokines & mediators upon TLR4 & TLR9 restimulation. PMID: 22357629
    6. TRIM30 is a negative regulator of NLRP3 inflammasome activation and provide insights into the role of TRIM30 in maintaining inflammatory responses. PMID: 21048113
    7. Tripartite-motif protein TRIM30alpha interacts with the TAB2-TAB3-TAK1 adaptor-kinase complex involved in the activation of transcription factor NF-kappaB. PMID: 18345001

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Nucleus.
  • 組織特異性:
    Highly expressed in spleen and lymph nodes (at protein level).
  • 數據庫鏈接:


主站蜘蛛池模板: 午夜精品射精入后重之免费观看| 中文字幕卡二和卡三的视频| 亚洲欧美综合成人五月天网站 | 让少妇爽到高潮视频| 亚洲精品www久久久| 国产精品永久免费| 久久这里只精品国产免费9| 五十路熟妇强烈无码| 精品乱子伦一区二区三区| 日本妇人成熟免费| 久草热8精品视频在线观看| 欧美日韩无砖专区一中文字| 东北女人啪啪对白| 欧美性xxxx极品少妇| 国内精品久久久久影院蜜芽 | 好想被狂躁无码视频在线观看| 亚洲日韩欧美国产高清αv| 高潮毛片无遮挡高清视频播放| 美女人妻激情乱人伦| 无码少妇一区二区三区视频| 婷婷丁香社区| 1000部又爽又黄无遮挡的视频| 色综合久久中文字幕有码| 日韩一区二区三区高清电影| 久久国产成人精品国产成人亚洲| 四虎国产精品一区二区| 国产国产裸模裸模私拍视频| 亚洲人成在线影院| 成年无码动漫av片在线观看羞羞| 亚洲国产成人久久一区久久| 国产精品原创av片国产日韩| 精品久久久噜噜噜久久久| 亚洲国产天堂久久久久久| 中国少妇xxxx做受| 欧美人妻日韩精品| 国产精品色情国产三级在| 久久66热人妻偷产精品9| 乱子伦视频在线看| 日韩av无码国产精品| 岛国在线无码高清视频| 欧美性猛交aaaa片黑人|