在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Transmembrane protein 119 (Tmem119), partial

Recombinant Mouse Transmembrane protein 119 (Tmem119), partial

  • 中文名稱：
    小鼠Tmem119重組蛋白
  • 貨號：
    CSB-YP023686MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Tmem119重組蛋白
  • 貨號：
    CSB-EP023686MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Tmem119重組蛋白
  • 貨號：
    CSB-EP023686MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Tmem119重組蛋白
  • 貨號：
    CSB-BP023686MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Tmem119重組蛋白
  • 貨號：
    CSB-MP023686MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Tmem119
  • Uniprot No.：
  • 別名：
    Tmem119; Transmembrane protein 119; Osteoblast induction factor; OBIF
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays an important role in bone formation and normal bone mineralization. Promotes the differentiation of myoblasts into osteoblasts. May induce the commitment and differentiation of myoblasts into osteoblasts through an enhancement of BMP2 production and interaction with the BMP-RUNX2 pathway. Upregulates the expression of ATF4 which plays a central role in osteoblast differentiation. Essential for normal spermatogenesis and late testicular differentiation.
  • 基因功能參考文獻：
    1. The first highly pure RNAseq profiles of microglia during development and after immune challenge show Tmem119 gene expression increases during development until P14 and then stabilizes. PMID: 26884166
    2. Obif plays essential roles in the development of multiple tissues, is required for bone mineralization and spermatogenesis. PMID: 26207632
    3. BMP-2 stimulates differentiation of myoblasts into osteoblasts via the PERK-eIF2alpha-ATF4 pathway but in addition stimulates Tmem119, which itself increases ATF4 PMID: 24362451
    4. Data show that Tmem119 promotes the differentiation of myoblasts into osteoblasts and the interaction with the BMP signaling pathway likely occurs downstream of Runx2 and Osterix in myoblasts. PMID: 22579779
    5. Obif plays an essential role in bone formation through regulating osteoblastogenesis. PMID: 22416756
    6. Parathyroid hormone-responsive Smad3-related factor, Tmem119, promotes osteoblast differentiation and interacts with the bone morphogenetic protein-Runx2 pathway. PMID: 21239498
    7. Study identifies a novel gene, obif (osteoblast induction factor), encoding a transmembrane protein that is predominantly expressed in osteoblasts. PMID: 20025746

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein. Cytoplasm. Endoplasmic reticulum membrane.
  • 組織特異性：
    Expressed in spermatocytes and spermatids in the developing testis (at protein level). Expressed in the brain, heart, lung, spleen, skeletal muscle, ovary, testis and epididymis. Predominantly expressed in osteoblasts.
  • 數據庫鏈接：


主站蜘蛛池模板： 尤物永久网站| 日本熟妇美熟bbw| 日本www网站色情乱码| 亚洲一区二区三区含羞草| 窝窝午夜看片| 狠狠综合久久av一区二区| 成人性生交大片免费看r老牛网站| 国内揄拍国内精品人妻浪潮av | 视频在线+欧美十亚洲曰本| 亚洲欧美偷国产日韩| 久久综合九色综合欧洲98| 欧洲熟妇色xxxx欧美老妇多毛| 国产午夜伦鲁鲁| 99久久国产自偷自偷免费一区 | 最近日本精品一卡2卡3卡4卡| 精品人妻va出轨中文字幕| 污污内射久久一区二区欧美日韩| 樱花草在线社区www| 一本大道久久东京热av| 久久综合色老色| 亚洲综合国产成人丁香五月激情| 国产精品你懂的在线播放| 国产欧美在线一区二区三| 少妇愉情理伦片丰满丰满| 国产露脸150部国语对白| 暖暖视频日本在线观看| 九个美女露脸撒尿嘘嘘视频| 成人女人黄网站免费视频| 亚洲熟妇无码av不卡在线| 日本免费大黄在线观看| 欧美高清精品一区二区| 2018年秋霞无码片| 97丨九色丨国产人妻熟女| 蜜臀av无码人妻精品| 久久亚洲精品无码播放| 国产精品va在线观看老妇女| 搡老熟女国产| 欧美乱码精品一区二区三区| 亚洲乱码中文论理电影| 欧美人与zoxxxx另类| 国产又粗又硬又大爽黄老大爷视|