在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Transmembrane protease serine 2 (Tmprss2), partial

Recombinant Mouse Transmembrane protease serine 2 (Tmprss2), partial

  • 中文名稱：
    小鼠Tmprss2重組蛋白
  • 貨號：
    CSB-YP884918MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Tmprss2重組蛋白
  • 貨號：
    CSB-EP884918MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Tmprss2重組蛋白
  • 貨號：
    CSB-BP884918MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Tmprss2重組蛋白
  • 貨號：
    CSB-MP884918MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Tmprss2; Transmembrane protease serine 2; EC 3.4.21.-; Epitheliasin; Plasmic transmembrane protein X) [Cleaved into: Transmembrane protease serine 2 non-catalytic chain; Transmembrane protease serine 2 catalytic chain]
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia.; (Microbial infection) Essential for spread and pathogenesis of influenza A virus (strains H1N1, H3N2 and H7N9) and is involved in proteolytic cleavage and activation of hemagglutinin (HA) protein which is essential for viral infectivity.
  • 基因功能參考文獻(xiàn)：
    1. Study shows that Influenza A (IAV) possessing a monobasic cleavage site in the haemagglutinin (HA) replicates poorly in TMPRSS2 knockout mice due to insufficient HA cleavage. On the contrary, IBV successfully underwent HA cleavage in TMPRSS2 knockout mice, and that the mouse-adapted strain was fully pathogenic. These data demonstrate a clear difference between IAV and IBV in their molecular mechanisms for spreading. PMID: 27389476
    2. DPP4:CD9:TTSP as the protein complexes are necessary for early efficient MERS-coronavirus entry. PMID: 28759649
    3. Genetic inhibition of TMPRSS2-ERG junction oncogene in prostate cancer by means of siRNA has strong antineoplastic effect in a mouse model and in vitro. PMID: 25933120
    4. The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis PMID: 25122198
    5. TMPRSS2 as a host cell factor essential for viral spread and pathogenesis of mono-basic H1N1 and H3N2 influenza A viruses. PMID: 24348248
    6. These results demonstrate that TMPRSS2 expression is essential for influenza A virus replication in vivo. PMID: 24600012
    7. These data demonstrate that TMPRSS2 is a host factor that is essential for pneumotropism and pathogenicity of H7N9 and H1N1 influenza virus in mice. PMID: 24522916
    8. Loss of TMPRSS2 serine protease activity does not influence fertility, reduce survival, result in prostate hyperplasia or carcinoma, or alter prostatic luminal epithelial cell regrowth following castration and androgen replacement. PMID: 16428450

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Single-pass type II membrane protein.; [Transmembrane protease serine 2 catalytic chain]: Secreted.
  • 蛋白家族：
    Peptidase S1 family
  • 組織特異性：
    Larynx, trachea and bronchi, lung, prostate and kidney.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 内射国产内射夫妻免费频道| 狠狠色噜噜狠狠狠888米奇视频| 国产精品久免费的黄网站| 久久国产欧美日韩精品图片| 亚洲欧美综合区丁香五月小说| 中文字幕日产熟女乱码| 亚洲成片在线观看12345 | 午夜福利视频1692| 国产公开免费人成视频| 青青草原综合久久大伊人精品| 亚洲中文字幕无码中文字在线| 免费又黄又爽1000禁片| 亚洲精品欧美精品日韩精品| 999久久久无码国产精品| 国产成年无码久久久免费| 国产精品久久久久久久免费看| 业余 自由 性别 成熟视频 视频| 久久精品国产99久久香蕉| 无码国产玉足脚交极品网站| 无码精品人妻一区二区三区98| 亚洲欭美日韩颜射在线| 影音先锋女人av鲁色资源网久久 | 亚洲国产区男人本色vr| 国产偷国产偷亚洲清高app| 丰满岳乱妇在线观看中字无码| 成在人线av无码免费看| 国产成人精品视频网站| 人妻系列无码一区二区三区| 免费人成视频在线播放| 伊人激情av一区二区三区| 亚洲色自偷自拍另类小说| 日本真人边吃奶边做爽动态图| 欧美专区另类专区在线视频| 欧美乱大交xxxxx潮喷l头像| 国产女人与公拘交在线播放| 国产超碰人人做人人爽av大片| 日本一区午夜艳熟免费| 日韩人妻无码一区二区三区| 欧美gv在线观看| 国产免费午夜福利在线播放11| 国产成人a区在线观看视频|