在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Transcription factor SOX-18 (Sox18)

Recombinant Mouse Transcription factor SOX-18 (Sox18)

  • 中文名稱：
    小鼠Sox18重組蛋白
  • 貨號：
    CSB-YP022425MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Sox18重組蛋白
  • 貨號：
    CSB-EP022425MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Sox18重組蛋白
  • 貨號：
    CSB-EP022425MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Sox18重組蛋白
  • 貨號：
    CSB-BP022425MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Sox18重組蛋白
  • 貨號：
    CSB-MP022425MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Sox18
  • Uniprot No.：
  • 別名：
    Sox18; Sox-18; Transcription factor SOX-18
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    1-377
  • 氨基酸序列
    MQRSPPGYGA QDDPPSRRDC AWAPGIGAAA EARGLPVTNV SPTSPASPSS LPRSPPRSPE SGRYGFGRGE RQTADELRIR RPMNAFMVWA KDERKRLAQQ NPDLHNAVLS KMLGKAWKEL NTAEKRPFVE EAERLRVQHL RDHPNYKYRP RRKKQARKVR RLEPGLLLPG LVQPSAPPEA FAAASGSARS FRELPTLGAE FDGLGLPTPE RSPLDGLEPG EASFFPPPLA PEDCALRAFR APYAPELARD PSFCYGAPLA EALRTAPPAA PLAGLYYGTL GTPGPFPNPL SPPPESPSLE GTEQLEPTAD LWADVDLTEF DQYLNCSRTR PDATTLPYHV ALAKLGPRAM SCPEESSLIS ALSDASSAVY YSACISG
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Transcriptional activator that binds to the consensus sequence 5'-AACAAAG-3' in the promoter of target genes and plays an essential role in embryonic cardiovascular development and lymphangiogenesis. Activates transcription of PROX1 and other genes coding for lymphatic endothelial markers. Plays an essential role in triggering the differentiation of lymph vessels, but is not required for the maintenance of differentiated lymphatic endothelial cells. Plays an important role in postnatal angiogenesis, where it is functionally redundant with SOX17. Interaction with MEF2C enhances transcriptional activation. Besides, required for normal hair development.
  • 基因功能參考文獻：
    1. Sox18 acts as a mesenchymal molecular switch necessary for the formation and function of the dermal papilla in all hair types. PMID: 28512199
    2. Sox18 genetically interacts with VegfC to regulate lymphangiogenesis in Zebrafish. PMID: 23520166
    3. SOX18 induction is a key step in mediating tumor lymphangiogenesis and metastasis PMID: 22523034
    4. Overexpression of wild-type SOX18 promoted capillary tube formation of HUVECs in vitro, whereas expression of dominant-negative SOX18 impaired tube formation of HUVECs and the migration of MCF-7 cells via the disruption of the actin cytoskeleton. PMID: 16882943
    5. These result can explain previously controversial data on the functional consequences of Sox18 mutations in mice and humans. PMID: 17603017
    6. findings demonstrate a critical role for Sox18 in developmental lymphangiogenesis, and suggest new avenues to investigate for therapeutic management of human lymphangiopathies PMID: 18931657
    7. SOX18 plays role in the vascular dysfunction in hypotrichosis-lymphedema-telangiectasia syndrome. PMID: 19429912
    8. Sox18 mRNA decreases during pulmonary hypertension induced by pulmonary fibrosis in mice. PMID: 17496152

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Detected in adult lung, heart and skeletal muscles.
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲成a v人片在线观看| 黄网站色视频免费国产| 欧洲熟妇色xxxxx视频 | 午夜福利不卡片在线机免费视频| 精品久久久中文字幕人妻| 无码国产69精品久久久久孕妇| 欧美高清精品一区二区| 亚洲精品无码成人aaa片| 韩国精品视频一区二区在线播放| 国产又黄又硬又粗| 国产成+人+综合+亚洲欧美丁香花| 在线资源天堂www| 麻豆国产av超爽剧情系列| 2018国产大陆天天弄| 青青草国产精品一区二区 | 永久免费看啪啪网址入口| 伊人色综合一区二区三区| 亚洲中文字幕无码人在线| 亚洲国产精品自在拍在线播放蜜臀| 无码一区二区三区在线| 伊人色综合久久天天五月婷| 伊人久久大香线蕉在观看| 2020精品国产自在现线官网| 国产精品网站在线观看免费传媒| 国产精品igao视频网| 亚洲精品入口一区二区乱麻豆精品 | 亚洲国产精品无码中文字2022| 99re6在线视频精品免费下载| 在线高清亚洲精品二区| 免费永久在线观看黄网站| 久久综合香蕉国产蜜臀av| 国产精品一区二区久久精品| 久久综合九色欧美婷婷| 鲁死你av资源站| 精品人伦一区二区三区潘金莲| 久久天天躁夜夜躁狠狠85台湾| 乱码国产丰满人妻www| 人妻熟女αⅴ一区二区三区| 久久中文精品无码中文字幕| 无码专区—va亚洲v专区| 在厨房拨开内裤进入毛片|