在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Transcription factor MafK (Mafk)

In Stock
  • 中文名稱:
    小鼠Mafk重組蛋白
  • 貨號:
    CSB-MP713990MO
  • 規格:
    ¥2640
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 85% as determined by SDS-PAGE.
  • 基因名:
    Mafk
  • Uniprot No.:
  • 別名:
    Mafk; Nfe2u; Transcription factor MafK; Erythroid transcription factor NF-E2 p18 subunit
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length
  • 來源:
    Mammalian cell
  • 分子量:
    21.5 kDa
  • 表達區域:
    1-156aa
  • 氨基酸序列
    MTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLKNRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFARTVARGPVTPTKVATTSVITIVKSAELSSTSVPFSAAS
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 10xHis-tagged and C-terminal Myc-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    Tris-based buffer,50% glycerol
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they act as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2, NFE2L1/NRF1, NFE2L2/NRF2 and NFE2L3/NRF3, and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor.
  • 基因功能參考文獻:
    1. beta-Cell-Specific Mafk Overexpression Impairs Pancreatic Endocrine Cell Development PMID: 26901059
    2. KAP-1 may contribute to the repression of Ey and beta-major globin gene transcription through recruitment to the promoters of these two genes, mediated by the interaction of KAP-1 with either Zfp445 or MafK, respectively PMID: 23291531
    3. regulation of dynamic exchange with Bach1 PMID: 14747657
    4. mafG::mafK::mafF triple-mutant fibroblasts that completely lack small Mafs are highly susceptible to oxidative stress. (mafK) PMID: 16135796
    5. DNA-binding activity of endogenous MafA was significantly increased in the MafK transgenic mice PMID: 16780794
    6. The involvement of both HNF4alpha and NF-E2 in Abcc6 gene regulation suggests that Abcc6 might be involved in a detoxification processes related to hemoglobin or heme. PMID: 16997394
    7. MafK/NF-E2 p18 recruitment was involved in the physical proximity of LCR and active beta-globin genes upon beta-globin gene transcriptional activation. PMID: 18308612
    8. Histological analysis revealed that embryonic development of beta cells in the MafA(-/-)MafK(+) mice was significantly suppressed and the reduced number of beta cells was responsible for the early onset of diabetes. PMID: 19715672

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    BZIP family, Maf subfamily
  • 組織特異性:
    Highly expressed in heart, skeletal muscle and placenta. Also expressed in erythroid cells.
  • 數據庫鏈接:


主站蜘蛛池模板: 中国女人内射6xxxxx| 色天使亚洲综合一区二区| 宝贝腿开大点我添添公视频免费| 1000部又爽又黄无遮挡的视频| 国产欧美亚洲精品a| 精品国产你懂的在线观看| 日韩国产丝袜人妻一二区| 国产欧美亚洲精品a第一页| 亚洲 日本 欧美 中文字幕| 五月开心播播网| 亚洲熟妇无码av不卡在线播放| 综合久久久久6亚洲综合| 熟女人妻一区二区三区免费看| 免费一区二区无码东京热| 久久不见久久见免费视频6无删减| 久久精品中文字幕一区二区三区 | 强开小婷嫩苞又嫩又紧视频| 人妻无码中文字幕永久在线| 人人妻一区二区三区| а天堂中文在线官网| 青青草国产免费久久久下载| 国产+日韩+另类+视频一区| 国产无遮挡裸体免费视频在线观看| 无遮18禁在线永久免费观看挡| 亚洲毛片无码不卡av在线播放| 全黄性性激高免费视频| 亚洲综合伊人久久大杳蕉| 影音先锋无码a∨男人资源站| 国产免费观看黄av片| 538在线精品视频| 国产精品人妻在线观看| 欧洲女人性开放免费网站| 久久亚洲精品国产精品777777| 国语精品一区二区三区| 九九re6热在线视频精品66| 亚洲色欲在线播放一区| 色猫咪av在线观看| 特黄大片又粗又大又暴| 国产精品久久久久久影视不卡| 无码国产精成人午夜视频| 亚洲精品国产自在现线看|