在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Trace amine-associated receptor 1 (Taar1), partial

Recombinant Mouse Trace amine-associated receptor 1 (Taar1), partial

  • 中文名稱：
    小鼠Taar1重組蛋白
  • 貨號：
    CSB-YP849748MO1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Taar1重組蛋白
  • 貨號：
    CSB-EP849748MO1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Taar1重組蛋白
  • 貨號：
    CSB-EP849748MO1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Taar1重組蛋白
  • 貨號：
    CSB-BP849748MO1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Taar1重組蛋白
  • 貨號：
    CSB-MP849748MO1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Taar1; Ta1; Tar1; Trar1; Trace amine-associated receptor 1; TaR-1; Trace amine receptor 1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Receptor for trace amines, including beta-phenylethylamine (b-PEA), p-tyramine (p-TYR), octopamine and tryptamine, with highest affinity for b-PEA and p-TYR. Unresponsive to classical biogenic amines, such as epinephrine and histamine and only partially activated by dopamine and serotonin. Trace amines are biogenic amines present in very low levels in mammalian tissues. Although some trace amines have clearly defined roles as neurotransmitters in invertebrates, the extent to which they function as true neurotransmitters in vertebrates has remained speculative. Trace amines are likely to be involved in a variety of physiological functions that have yet to be fully understood. The signal transduced by this receptor is mediated by the G(s)-class of G-proteins which activate adenylate cyclase.
  • 基因功能參考文獻：
    1. These results indicate that activation of TAAR1 potentiates MA-induced hypothermia and TAAR1 confers sustained neuroprotection dependent on its thermoregulatory effects. PMID: 28919515
    2. The Taar1 gene is within a mouse chromosome 10 quantitative trait locus for methamphetamine consumption, and TAAR1 function determines sensitivity to aversive effects of methamphetamine that may curb intake PMID: 27055611
    3. SNP-induced changes in mouse TAAR1 function PMID: 27031617
    4. Behavioral and physiological studies indicate that TAAR1 function increases sensitivity to aversive effects of Methamphetamine, and may thereby protect against Methamphetamine use. PMID: 25740289
    5. This study demonstrated that TAAR1 Modulates Cortical Glutamate NMDA Receptor Function in mouse. PMID: 25749299
    6. This study report that TAAR1 potentiates the degeneration of dopaminergic neurons and attenuates the behavioral response to l-DOPA and presynaptic and postsynaptic glutamate neurotransmission in the striatum. PMID: 26468205
    7. These data demonstrate supersensitivity of postsynaptic D2 dopamine receptors in the striatum of TAAR1-KO mice and indicate that a close interaction of TAAR1 and D2 dopamine receptors. PMID: 25721394
    8. The data of this study indicated that apomorphine activity at TAAR1 contributes to some behavioral manifestations, particularly climbing. PMID: 24925023
    9. This study demonistrar=ted that Taar1-mediated modulation of presynaptic dopaminergic neurotransmission: role of D2 dopamine autoreceptors. PMID: 24565640
    10. These observations confirm the modulatory role of TAAR1 on monoamine activity and suggest that in vivo the receptor is either constitutively active and/or tonically activated by ambient levels of endogenous agonists PMID: 22763617
    11. Data show that TAARs were expressed only at trace amounts in most of the tissues, the exceptions being TAAR1 in stomach and testis and TAAR8a in intestine, spleen, and testis. PMID: 22442117
    12. Data support that TAAR1 tonically activates inwardly rectifying K(+) channels, which reduces the basal firing frequency of dopamine neurons in the ventral tegmental area. PMID: 19892733
    13. Expression of neuronal trace amine-associated receptor (Taar) mRNAs in leukocytes. PMID: 17900709
    14. Trace amine-associated receptor 1 (TAAR1) activity decreases the spontaneous firing rate of dopaminergic neurons in the ventral tegmental area. PMID: 18083911
    15. Previous studies reported TAAR expression in brain. This paper found TAAR expression only in olfactory epithelial cells and that each TAAR detects a unique set of amine ligands. TAARs seem to function as a family of chemosensory receptors for amines. PMID: 16878137

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 組織特異性：
    Widely distributed throughout the brain. Strongly expressed in the mitral cell layer of the olfactory bulb, piriform cortex, the arcuate, motor, and mesencephalic trigeminal nuclei, lateral reticular and hypoglossal nuclei, cerebellar Purkinje cells, and
  • 數據庫鏈接：


主站蜘蛛池模板： 深夜福利啪啪片| 精品国产品香蕉在线| 精品无码国产一区二区三区51安| 国产成人人人97超碰超爽8| 欧美性猛交xxx嘿人猛交| 久久久婷婷五月亚洲97号色| 亚洲另类无码专区丝袜| 四虎国产精品永久地址入口| 亚洲r成人av久久人人爽| 性一交一乱一乱一视频| 亚洲一区二区三区国产精华液| 久久精品中文无码资源站| 天美传媒精品1区2区3区| 黑人与人妻无码中字视频| 中文字幕亚洲综合久久菠萝蜜| 日日噜噜夜夜爽爽| 又粗又黄又硬又爽的免费视频| 伊人婷婷色香五月综合缴缴情| 久久精品人人做人人爱爱漫画| 中文字幕无码第1页| 男ji大巴进入女人的视频小说 | 果冻传媒mv免费播放在线观看| 美女露出粉嫩小奶头在视频18禁| 婷婷成人综合激情在线视频播放 | 丁香狠狠色婷婷久久综合| 久久久久人妻一区二区三区| 色综合中文综合网| 狠狠做深爱婷婷丁香综合| 国产精品美女久久久m| 日韩在线不卡免费视频一区| 欧美性受xxxx黑人xyx性爽| 国产成人精品自在线导航| 亚洲另类欧美综合久久图片区| 乱人伦人妻中文字幕无码久久网| 欧美z0zo人禽交欧美人禽交| 日韩视频无码免费一区=区三区| 202丰满熟女妇大| 爆爽久久久一区二区又大又黄又嫩| 97国语精品自产拍在线观看| 久久久久久久精品成人热色戒汤唯| 中文字幕无码视频专区|