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  4. Recombinant Mouse TOX high mobility group box family member 3 (Tox3)

Recombinant Mouse TOX high mobility group box family member 3 (Tox3)

  • 中文名稱：
    小鼠Tox3重組蛋白
  • 貨號：
    CSB-YP024075MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Tox3重組蛋白
  • 貨號：
    CSB-EP024075MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Tox3重組蛋白
  • 貨號：
    CSB-EP024075MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Tox3重組蛋白
  • 貨號：
    CSB-BP024075MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Tox3重組蛋白
  • 貨號：
    CSB-MP024075MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Tox3
  • Uniprot No.：
  • 別名：
    Tox3; Tnrc9; TOX high mobility group box family member 3; Trinucleotide repeat-containing gene 9 protein
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-575
  • 氨基酸序列
    MDVRFYPAAA GDPAGLDFAQ CLGYYGYSKL GNNNYMNMAE ANNAFFAASE QTFHTPSLGD EEFEIPPITP PPESDPTLGM PDALLPFQTL SDPLPSQGTE FTPQFPPQSL DLPSITISRN LVEQDGVLHS NGLHMDQSHT QVSQYRQDPS LVMRSIVHMT DGARSGIMPP AQLTTINQSQ LSAQLGLNLG GANVSHTSPS PPASKSATPS PSSSINEEDA DDANRAIGEK RTAPDSGKKP KTPKKKKKKD PNEPQKPVSA YALFFRDTQA AIKGQNPNAT FGEVSKIVAS MWDSLGEEQK QVYKRKTEAA KKEYLKALAA YRASLVSKAA AESAEAQTIR SVQQTLASTN LTSSLLLNTS LSQHGTVPAS PQTLPQSLPR SIAPKPLTMR LPMSQIVTSV TIAANMPSNI GAPLISSMGT TMVGSATSTQ VSPSVQTQQH QMQLQQQQQQ QQQMQQMQQQ QLQQHQMHQQ IQQQMQQQHF QHHMQQHLQQ QQQQHLQQQL SQQQLQQQLQ QHLQLQQLQH MQHQSQPSPR QHSPVTSQIT SPIPAIGSPQ PASQQHQPQI QSQTQTQVLP QVSIF
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Transcriptional coactivator of the p300/CBP-mediated transcription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region.
  • 基因功能參考文獻：
    1. A role of Tox3 in the development of the nervous system. PMID: 27080130
    2. data suggest that central inhibition of IL-1alpha or Tox3 overexpression during the acute phase of a CNS insult may be an effective means for preventing the loss of neurological function PMID: 26224856
    3. TNRC9 gene is amplified and associated with poor prognosis in advanced breast cancer. TNRC9 promotes cancer cell proliferation, migration, and survival both in vitro and in vivo. TNRC9 and BRCA1 expression are inversely correlated. PMID: 23447579
  • 亞細胞定位：
    Nucleus.
  • 數(shù)據(jù)庫鏈接：


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