在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse TNF receptor-associated factor 5 (Traf5)

Recombinant Mouse TNF receptor-associated factor 5 (Traf5)

  • 中文名稱：
    小鼠Traf5重組蛋白
  • 貨號：
    CSB-YP024153MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Traf5重組蛋白
  • 貨號：
    CSB-EP024153MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Traf5重組蛋白
  • 貨號：
    CSB-EP024153MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Traf5重組蛋白
  • 貨號：
    CSB-BP024153MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Traf5重組蛋白
  • 貨號：
    CSB-MP024153MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Traf5; TNF receptor-associated factor 5
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    1-558
  • 氨基酸序列
    MAHSEEQAAV PCAFIRQNSG NSISLDFEPD TEYQFVEQLE ERYKCAFCHS VLHNPHQTGC GHRFCQQCIR SLRELNSVPI CPVDKEVIKP QEVFKDNCCK REVLNLHVYC KNAPGCNARI ILGRFQDHLQ HCSFQAVPCP NESCREAMLR KDVKEHLSAY CRFREEKCLY CKRDIVVTNL QDHEENSCPA YPVSCPNRCV QTIPRARVNE HLTVCPEAEQ DCPFKHYGCT VKGKRGNLLE HERAALQDHM LLVLEKNYQL EQRISDLYQS LEQKESKIQQ LAETVKKFEK ELKQFTQMFG RNGTFLSNVQ ALTSHTDKSA WLEAQVRQLL QIVNQQPSRL DLRSLVDAVD SVKQRITQLE ASDQRLVLLE GETSKHDAHI NIHKAQLNKN EERFKQLEGA CYSGKLIWKV TDYRVKKREA VEGHTVSVFS QPFYTSRCGY RLCARAYLNG DGSGKGTHLS LYFVVMRGEF DSLLQWPFRQ RVTLMLLDQS GKKNHIVETF KADPNSSSFK RPDGEMNIAS GCPRFVSHST LENSKNTYIK DDTLFLKVAV DLTDLEDL
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR.
  • 基因功能參考文獻：
    1. TRAF5 is crucially involved in OSM-mediated lung inflammation probably by inducing lung stromal/fibroblast cell activation. PMID: 29596835
    2. our data indicate that Berberine exerts protective effects against chronic renal failurepartly through the TRAF5-mediated activation of the NF-kappaB signaling pathway in mouse podocytes PMID: 29115406
    3. The results indicated that TRAF5 deficiency significantly aggravated DSS-induced colitis, most likely by regulating Th cell-mediated inflammation. PMID: 27110068
    4. In conclusion, our results suggest that as an intrinsic cardioprotective factor, TRAF5 plays a crucial role in the development of cardiac hypertrophy through the negative regulation of the MEK-ERK1/2 pathway PMID: 24038435
    5. knock-out mice develop exaggerated experimental autoimmune encephalomyelitis due to enhanced Th17 cell differentiation PMID: 24681564
    6. TRAF5 negatively regulates TLR signaling in B lymphocytes. PMID: 24259503
    7. These results provide the first demonstration that TRAF5 is a critical mediator of brain ischemia/reperfusion in an experimental stroke model. PMID: 23413803
    8. Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF). PMID: 21822258
    9. TNF receptor-associated factor 5 (TRAF5) deficiency accelerates atherogenesis in mice by increasing inflammatory cell recruitment and foam cell formation. PMID: 20651286
    10. Study is the first report showing a major requirement for TRAF5 in signaling by a specific receptor both in vitro and in vivo, as well as playing an important role in biological function in B lymphocytes. PMID: 19805155
    11. role in both RANKL- and TNFalpha-induced osteoclastogenesis PMID: 12619928
    12. TRAF5 has a role in TNF-alpha induced IKK phosphorylation of NF-kappaB p65 PMID: 12842894
    13. TRAF5 plays a limiting role during the differentiation of type 2 helper (Th2) cells by limiting certain responses driven by costimulatory molecules such as OX40/CD134. PMID: 15034043
    14. Traf5 is a critical intermediate of costimulatory signaling pathways triggered by glucocorticoid-induced TNFR in T-lymphocytes. PMID: 16452475
    15. TRAF5 as an important positive signaling element that enhances T cell expansion and pathogen containment by providing a survival advantage to responding Ag-specific CD8(+) T cells during infection. PMID: 19017969

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cytoplasm, cytosol.
  • 蛋白家族：
    TNF receptor-associated factor family, A subfamily
  • 數據庫鏈接：

    KEGG: mmu:22033

    UniGene: Mm.380491



主站蜘蛛池模板： 色偷偷女人的天堂亚洲网| 亚洲成av人片在www色猫咪| 成年女人免费视频播放体验区| 亚洲第一av网站| 国产亚洲日韩在线三区| 无码不卡中文字幕av| 中文字幕中文有码在线| 插插插精品亚洲一区| 国产乱码二卡3卡四卡| 日韩免费视频| 99精品久久久久久久婷婷| 国产成人欧美亚洲日韩电影| 国产成人精品a∨一区二区| 午夜亚洲精品久久一区二区| 亚洲成a人v欧美综合天堂麻豆| 亚洲精品一品区二品区三品区 | av亚欧洲日产国码无码| 国产精品国产三级国产剧情| 中文字幕日本乱码仑区在线| 日本免费一区二区三区视频观看| 国产免费无遮挡吸奶头视频| 欧美日韩人人模人人爽人人喊| 97无码精品综合| 边喂奶边中出的人妻| 一边摸一边抽搐一进一出视频| 亚洲中文字幕无码av永久| 亚洲龙腾成小说人网| 中文字幕制服丝袜第57页| 大陆国语对白国产av片| 老妇高潮潮喷到猛进猛出| 曰批免费视频播放免费直播| 亚洲.欧美.在线视频| 国产av熟女一区二区三区| 免费无码av一区二区| 西西444www大胆无码视频| 久久www免费人成_看片老司机| 国精产品一区一区三区mba下载| 少妇人妻综合久久中文字幕| 免费现黄频在线观看国产| 欧美疯狂xxxxbbbb喷潮| 人妻少妇精品中文字幕av|