在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse THO complex subunit 4 (Alyref)

Recombinant Mouse THO complex subunit 4 (Alyref)

  • 中文名稱：
    Recombinant Mouse THO complex subunit 4(Alyref)
  • 貨號：
    CSB-YP023504MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse THO complex subunit 4(Alyref)
  • 貨號：
    CSB-EP023504MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse THO complex subunit 4(Alyref)
  • 貨號：
    CSB-EP023504MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse THO complex subunit 4(Alyref)
  • 貨號：
    CSB-BP023504MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse THO complex subunit 4(Alyref)
  • 貨號：
    CSB-MP023504MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Alyref
  • Uniprot No.：
  • 別名：
    Alyref; Aly; Ref1; Refbp1; THOC4; THO complex subunit 4; Tho4; Ally of AML-1 and LEF-1; Aly/REF export factor; REF1-I; RNA and export factor-binding protein 1; Transcriptional coactivator Aly/REF
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-255
  • 氨基酸序列
    ADKMDMSLD DIIKLNRSQR GGRGGGRGRG RAGSQGGRGG AVQAAARVNR GGGPMRNRPA IARGAAGGGR NRPAPYSRPK QLPDKWQHDL FDSGFGGGAG VETGGKLLVS NLDFGVSDAD IQELFAEFGT LKKAAVHYDR SGRSLGTADV HFERKADALK AMKQYNGVPL DGRPMNIQLV TSQIDTQRRP AQSINRGGMT RNRGSGGFGG GGTRRGTRGG SRGRGRGTGR NSKQQLSAEE LDAQLDAYNA RMDTS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm. TREX recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production; ALYREF/THOC4 mediates the recruitment of the TREX complex to the intronless viral mRNA. Required for TREX complex assembly and for linking DDX39B to the cap-binding complex (CBC). In conjunction with THOC5 functions in NXF1-NXT1 mediated nuclear export of HSP70 mRNA; both proteins enhance the RNA binding activity of NXF1 and are required for NXF1 localization to the nuclear rim. Involved in the nuclear export of intronless mRNA; proposed to be recruited to intronless mRNA by ATP-bound DDX39B. Involved in transcription elongation and genome stability. Involved in mRNA export of C5-methylcytosine (m5C)-containing mRNAs: specifically recognizes and binds m5C mRNAs and mediates their nucleo-cytoplasmic shuttling.; Acts as chaperone and promotes the dimerization of transcription factors containing basic leucine zipper (bZIP) domains and thereby promotes transcriptional activation.
  • 基因功能參考文獻：
    1. Structure of the nuclear factor ALY provides insights into post-transcriptional regulatory and mRNA nuclear export processes. PMID: 12809490
  • 亞細胞定位：
    Nucleus. Nucleus speckle. Cytoplasm.
  • 蛋白家族：
    THOC4 family
  • 組織特異性：
    Highly expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis.
  • 數據庫鏈接：


主站蜘蛛池模板： 国产人妻精品区一区二区三区| 免费无码毛片一区二三区| 长腿校花无力呻吟娇喘| 国产成人精品视频网站| 免费观看又色又爽又湿的视频| 后入到高潮免费观看| 中文字幕无码不卡一区二区三区| 中文字幕无码日韩欧免费软件| 亚洲成av人片在www鸭子| 九九精品无码专区免费| 三男一女吃奶添下面视频| 亚洲 欧美 另类图片| 亚洲一二区制服无码中字| 国产高清无密码一区二区三区| 欧美 丝袜 自拍 制服 另类| 久久综合给合久久国产免费| 欧美综合区自拍亚洲综合绿色| 国模丽丽啪啪一区二区| 亚洲精品久久国产高清情趣图文| 免费播放一区二区三区| 国产ktv交换配乱婬视频| 天天摸夜夜添狠狠添婷婷| 女人张开腿让男人桶个爽| 久久久久蜜桃精品成人片| 国产未成女一区二区| 肉色超薄丝袜脚交一区二区| 国产v亚洲v天堂无码久久久| 成人做受视频试看120秒| 99在线精品视频观看免费| 99久久免费精品高清特色大片| 2018年亚洲欧美在线v| √天堂资源中文| 久久人妻av无码中文专区| 欧美黑人粗大xxxxbbbb| 男人的天堂免费一区二区视频| 无码人妻h动漫| 亚洲精品乱码久久久久久不卡| 青青草国产线观看| 免费看又色又爽又黄的国产软件| 久久婷婷五月综合色99啪| 国产情侣真实54分钟在线|