在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse THO complex subunit 4 (Alyref)

Recombinant Mouse THO complex subunit 4 (Alyref)

  • 中文名稱：
    Recombinant Mouse THO complex subunit 4(Alyref)
  • 貨號：
    CSB-YP023504MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse THO complex subunit 4(Alyref)
  • 貨號：
    CSB-EP023504MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse THO complex subunit 4(Alyref)
  • 貨號：
    CSB-EP023504MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse THO complex subunit 4(Alyref)
  • 貨號：
    CSB-BP023504MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse THO complex subunit 4(Alyref)
  • 貨號：
    CSB-MP023504MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Alyref
  • Uniprot No.：
  • 別名：
    Alyref; Aly; Ref1; Refbp1; THOC4; THO complex subunit 4; Tho4; Ally of AML-1 and LEF-1; Aly/REF export factor; REF1-I; RNA and export factor-binding protein 1; Transcriptional coactivator Aly/REF
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-255
  • 氨基酸序列
    ADKMDMSLD DIIKLNRSQR GGRGGGRGRG RAGSQGGRGG AVQAAARVNR GGGPMRNRPA IARGAAGGGR NRPAPYSRPK QLPDKWQHDL FDSGFGGGAG VETGGKLLVS NLDFGVSDAD IQELFAEFGT LKKAAVHYDR SGRSLGTADV HFERKADALK AMKQYNGVPL DGRPMNIQLV TSQIDTQRRP AQSINRGGMT RNRGSGGFGG GGTRRGTRGG SRGRGRGTGR NSKQQLSAEE LDAQLDAYNA RMDTS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm. TREX recruitment occurs via an interaction between ALYREF/THOC4 and the cap-binding protein NCBP1. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production; ALYREF/THOC4 mediates the recruitment of the TREX complex to the intronless viral mRNA. Required for TREX complex assembly and for linking DDX39B to the cap-binding complex (CBC). In conjunction with THOC5 functions in NXF1-NXT1 mediated nuclear export of HSP70 mRNA; both proteins enhance the RNA binding activity of NXF1 and are required for NXF1 localization to the nuclear rim. Involved in the nuclear export of intronless mRNA; proposed to be recruited to intronless mRNA by ATP-bound DDX39B. Involved in transcription elongation and genome stability. Involved in mRNA export of C5-methylcytosine (m5C)-containing mRNAs: specifically recognizes and binds m5C mRNAs and mediates their nucleo-cytoplasmic shuttling.; Acts as chaperone and promotes the dimerization of transcription factors containing basic leucine zipper (bZIP) domains and thereby promotes transcriptional activation.
  • 基因功能參考文獻：
    1. Structure of the nuclear factor ALY provides insights into post-transcriptional regulatory and mRNA nuclear export processes. PMID: 12809490
  • 亞細胞定位：
    Nucleus. Nucleus speckle. Cytoplasm.
  • 蛋白家族：
    THOC4 family
  • 組織特異性：
    Highly expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis.
  • 數據庫鏈接：


主站蜘蛛池模板： 色多多www视频在线观看免费| 99精品视频一区在线观看| 日本亚洲欧美在线视观看| 中文字幕精品久久久久人妻红杏 | 无码国产69精品久久久孕妇| 三上悠亚ssⅰn939无码播放| 日韩熟女精品一区二区三区| 无码人妻丰满熟妇区五十路| 98久久人妻少妇激情啪啪| av激情亚洲男人的天堂| 国产手机精品一区二区| 国产亚洲婷婷香蕉久久精品 | 2020年无码国产精品高清免费| 久久精品国产99国产精2021| 人人超人人超碰超国产97超碰| 波多野结衣美乳人妻hd电影欧美| 婷婷色婷婷开心五月| 饥渴丰满少妇大力进入| 国产精品无码一区二区在线看| 国产三级做爰在线播放| 国产福利一区二区三区在线观看 | 国产农村乱辈无码| 欧美无遮挡很黄裸交视频| 国产成人综合久久亚洲精品| 国产69久久精品成人看| 97视频热人人精品免费| 99精品免视看| 国产精品毛片无遮挡高清| 人妻夜夜爽天天爽三区麻豆av网站 | 日本十八禁黄无遮禁视频免费| 欧洲一卡2卡3卡4卡乱码视频 | 国产午夜永久福利视频在线观看| 亚洲精品少妇30p| 久久亚洲精品中文字幕| 国产av区男人的天堂| 国产三级在线观看播放视频| 成人天堂婷婷青青视频在线观看 | 久久午夜夜伦鲁鲁片免费无码| 国产色播av在线观看| 日韩精品专区在线影院重磅| 亚洲精品久久久久久中文|