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  4. Recombinant Mouse TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (Taf6l)

Recombinant Mouse TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (Taf6l)

  • 中文名稱：
    小鼠Taf6l重組蛋白
  • 貨號：
    CSB-YP840275MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Taf6l重組蛋白
  • 貨號：
    CSB-EP840275MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Taf6l重組蛋白
  • 貨號：
    CSB-EP840275MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Taf6l重組蛋白
  • 貨號：
    CSB-BP840275MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Taf6l重組蛋白
  • 貨號：
    CSB-MP840275MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Taf6l
  • Uniprot No.：
  • 別名：
    Taf6l; Paf65a; TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L; TAF6L; PCAF-associated factor 65-alpha; PAF65-alpha
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-616
  • 氨基酸序列
    MSEREERRFV EIPRESVRLM AESTGLELSD EVAALLAEDV CYRLREATQN SSQFMKHTKR RKLTVEDFNR ALRWSSVEAV CGYGSQEALP LRPAREGDLY FPEDREVSLV ELALATNIPK GCAETAVRVH VSYLDGKGNL APQGSVPSAV SSLTDDLLKY YQQVTRAVLG DDPQLMKVAL QDLQTNSKIA ALLPYFVYVV SGVKSVSHDL EQLHRLLQVA RSLIRNPHLC LGPYVRSLVG SVLYCVLEPL AASINPLNDH WTLRDGAALL LSHIFWTHGD LVSGLYQQIL LSLQKVLTDP VRPLCSHYGA VVGLHALGWK AVERVLYPHL PTYWTNLQAV LDDYSVSNAQ VKADGHKVYG AILVAVERLL KMKAQAAEPN RGGLGGRGYR PAEDLPWDSL LLQESPPGGS SETGFGSGLP PPSGVAGPED PSSLTLADIY RELYSFFGDS LATRFGTGQP APTAPRPPGD KKEPAAAPDS VRKMPQLTAS AVVSPQGDES PCGGTLATAT AASESRPLPR VHRARGAPRQ QGPGAGTRDV FQKSRFAPRG APHFRFIIAG RQAGRRCRGR LFQTAFPAPY GPSPASRYVQ KLPMIGRTGR PARRWALSDY SLYLPL
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. With TAF5L, acts as an epigenetic regulator essential for somatic reprogramming. Regulates target genes through H3K9ac deposition and MYC recruitment which trigger MYC regulatory network to orchestrate gene expression programs to control embryonic stem cell state. Functions with MYC to activate target gene expression through RNA polymerase II pause release.
  • 基因功能參考文獻：
    1. Gonadotropin-releasing hormone-mediated phosphorylation of ERalpha in LbetaT2 pituitary cells results in its rapid association with p300-CBP-associated factor and the transcriptional activation of fosB. PMID: 19574399
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    TAF6 family
  • 數據庫鏈接：


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