在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse T-cell surface glycoprotein CD8 beta chain (Cd8b), partial

  • 中文名稱:
    Recombinant Mouse T-cell surface glycoprotein CD8 beta chain(Cd8b),partial
  • 貨號:
    CSB-YP004967MO1
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    Recombinant Mouse T-cell surface glycoprotein CD8 beta chain(Cd8b),partial
  • 貨號:
    CSB-EP004967MO1
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    Recombinant Mouse T-cell surface glycoprotein CD8 beta chain(Cd8b),partial
  • 貨號:
    CSB-EP004967MO1-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    Recombinant Mouse T-cell surface glycoprotein CD8 beta chain(Cd8b),partial
  • 貨號:
    CSB-BP004967MO1
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    Recombinant Mouse T-cell surface glycoprotein CD8 beta chain(Cd8b),partial
  • 貨號:
    CSB-MP004967MO1
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Cd8b; Cd8b1; Ly-3; Lyt-3; Lyt3; T-cell surface glycoprotein CD8 beta chain; Lymphocyte antigen 3; T-cell membrane glycoprotein Ly-3; T-cell surface glycoprotein Lyt-3; CD antigen CD8b
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能:
    Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched. Once LCK recruited, it initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of cytotoxic T-lymphocytes (CTLs). Additionally, plays a critical role in thymic selection of CD8+ T-cells.
  • 基因功能參考文獻(xiàn):
    1. We propose that ADP-ribosylation of CD8-beta can regulate the coreceptor function of CD8 in the presence of elevated levels of extracellular NAD(+) . PMID: 23575529
    2. sialylation in a discrete segment of the CD8beta stalk by ST3Gal-1 sialyltransferase creates a molecular developmental switch that affects ligand binding PMID: 12459555
    3. The stalk region of CD8 beta is capable of fine-tuning the coreceptor function of CD8 proteins as a coreceptor, possibly due to its distinct protein structure, smaller physical size and the unique glycan adducts associated with this region. PMID: 12847256
    4. The stalk region of CD8beta influences the ability of CD8 to bind class I major histocompatibility complexes and is therefore critical for the correct functioning of CD8alphabeta heterodimers. PMID: 19109142
    5. The crystal structure of CD8alphabeta in complex with H-2Dd antigen indicates that CD8beta is crucial in orienting the CD8alphabeta heterodimer. PMID: 19625641

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Membrane; Single-pass type I membrane protein.
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 亚洲精品无码久久久| 四虎国产精亚洲一区久久特色| 国产美女自卫慰水免费视频| 成人网站精品久久久久| 国产激情一区二区三区| 国产精品十八禁在线观看| 国产精品久久婷婷六月丁香 | 久久婷婷是五月综合色| 成人无码影片精品久久久| 日韩久久无码免费毛片软件 | 中文字幕亚洲无线码一区女同| 亚洲欧美日本中文字不卡| 国产免费二卡3卡四卡| 一本久久知道综合久久| 欧美mv日韩mv国产网站app| av无码国产在线观看岛国| 伊伊人成亚洲综合人网| 欧美天天综合色影久久精品| 99久久久国产精品无码免费| 欧美日韩无套内射另类| 国产av无码专区亚洲aⅴ| 色婷婷综合缴情综免费观看| 麻豆一区二区三区精品视频| 国产日产欧产美| 成人片黄网站a毛片免费观看| 137肉体摄影日本裸交| 99久久精品无码一区二区三区| 婷婷五月综合丁香在线| 久久精品国自产拍| 丰满人妻中伦妇伦精品app | 自慰系列无码专区| 日产精品卡2卡三卡乱码网站 | 三个男人躁我一个爽视频免费| 久久久久久久久久久久久9999| 无码高潮少妇毛多水多水免费| 最新亚洲精品国偷自产在线| 狠狠躁天天躁无码中文字幕| 99久久综合精品五月天| 色v99在线影院| 亚洲一区二区av在线观看| xx性欧美肥妇精品久久久久久|