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  4. Recombinant Mouse Synaptic vesicle glycoprotein 2B (Sv2b), partial

Recombinant Mouse Synaptic vesicle glycoprotein 2B (Sv2b), partial

  • 中文名稱：
    小鼠Sv2b重組蛋白
  • 貨號：
    CSB-YP022979MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Sv2b重組蛋白
  • 貨號：
    CSB-EP022979MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Sv2b重組蛋白
  • 貨號：
    CSB-EP022979MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Sv2b重組蛋白
  • 貨號：
    CSB-BP022979MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Sv2b重組蛋白
  • 貨號：
    CSB-MP022979MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Sv2b
  • Uniprot No.：
  • 別名：
    Sv2b; Kiaa0735; Synaptic vesicle glycoprotein 2B; Synaptic vesicle protein 2B
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Probably plays a role in the control of regulated secretion in neural and endocrine cells.; (Microbial infection) Receptor for C.botulinum neurotoxin type A (BoNT/A, botA); the toxin probably binds via extracellular loop 4.; (Microbial infection) Possible receptor for C.botulinum neurotoxin type D (BoNT/D, botD). Not a receptor for C.botulinum neurotoxin type D (BoNT/D, botD).; (Microbial infection) Receptor for C.botulinum neurotoxin type E (BoNT/E); the toxin probably binds via extracellular loop 4. It probably requires glycosylation of Asn-516.
  • 基因功能參考文獻：
    1. To study the role of SV2B in maintaining the podocyte function and to better understand the function of the neuron-like vesicle expressing SV2B in the podocyte, we analyzed them with SV2B knockout (KO) mice. PMID: 25730372
    2. Glutamatergic & GABAergic transmission are unaffected by deletion of the SV2B protein. Additional deletion of SV2B does not affect the electrophysiological phenotype of SV2A deletion. PMID: 22847229
    3. Loss of synaptic vesicle glycoprotein 2b is associated with inhibition of tetanus neurotoxin into central neurons. PMID: 21124874
    4. SV2 controls key aspects of synaptic functionality via its ability to regulate presynaptic Ca(2+). PMID: 20620874
    5. SV2B contributes to the modulation of synaptic vesicle exocytosis and plays a significant role in regulating synaptic protein content PMID: 19381277

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  • 亞細胞定位：
    Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, acrosome.
  • 蛋白家族：
    Major facilitator superfamily
  • 組織特異性：
    Expressed in ribbon synapses of the retina (at protein level). Expressed in diaphragm motor nerve terminals (at protein level). Expressed in hippocampus neurons (at protein level).
  • 數據庫鏈接：


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