在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Stimulated by retinoic acid gene 6 protein (Stra6), partial

Recombinant Mouse Stimulated by retinoic acid gene 6 protein (Stra6), partial

  • 中文名稱：
    小鼠Stra6重組蛋白
  • 貨號(hào)：
    CSB-YP022872MO
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Stra6重組蛋白
  • 貨號(hào)：
    CSB-EP022872MO
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Stra6重組蛋白
  • 貨號(hào)：
    CSB-EP022872MO-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Stra6重組蛋白
  • 貨號(hào)：
    CSB-BP022872MO
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Stra6重組蛋白
  • 貨號(hào)：
    CSB-MP022872MO
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Stra6
  • Uniprot No.：
  • 別名：
    Stra6; Receptor for retinol uptake STRA6; Retinoic acid-responsive protein; Retinol-binding protein receptor STRA6; Stimulated by retinoic acid gene 6 protein
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Functions as retinol transporter. Accepts all-trans retinol from the extracellular retinol-binding protein RBP4, facilitates retinol transport across the cell membrane, and then transfers retinol to the cytoplasmic retinol-binding protein RBP1. Retinol uptake is enhanced by LRAT, an enzyme that converts retinol to all-trans retinyl esters, the storage forms of vitamin A. Contributes to the activation of a signaling cascade that depends on retinol transport and LRAT-dependent generation of retinol metabolites that then trigger activation of JAK2 and its target STAT5, and ultimately increase the expression of SOCS3 and inhibit cellular responses to insulin. Important for the homeostasis of vitamin A and its derivatives, such as retinoic acid and 11-cis-retinal. STRA6-mediated transport is particularly important in the eye, and under conditions of dietary vitamin A deficiency. Does not transport retinoic acid.
  • 基因功能參考文獻(xiàn)：
    1. The STRA6 is potent regulators of diurnal insulin responses and suggest that the holo-RBP/STRA6 signaling axis may represent a novel therapeutic target in type II diabetes. PMID: 28733465
    2. Suppression of STRA6 cascades is involved in renal apoptosis and fibrosis caused by electronegative low density lipoproteins. PMID: 27256691
    3. These results showed that STRA6 is critical for vitamin A homeostasis and the adaption of this process to the fluctuating supply of the vitamin.- PMID: 27189978
    4. Studies indicate that STRA6 is indeed a bona fide vitamin A transporter and provide novel insights into the regulatory mechanism that governs vitamin A homeostasis in peripheral tissues. PMID: 24852372
    5. Total vitamin A levels are dramatically lower in the eyes of STRA6 KO mice as compared to those of WT mice, but the levels in other organs were not significantly affected after STRA6 deletion under vitamin A sufficient conditions. PMID: 24391722
    6. STRA6 reduction in adipocytes in adipose-Stra6(-/-) mice. PMID: 24421389
    7. Rbp4 and its membrane receptor STRA6 control adipogenesis by regulating cellular retinoid homeostasis and RARalpha activity. PMID: 23959802
    8. STRA6 in tissues other than the eye appears to be the coupling of circulating holo-RBP levels to cell signaling, in turn regulating key processes such as insulin response. PMID: 23839944
    9. Stra6, a retinoic acid-responsive gene, participates in p53-induced apoptosis after DNA damage. PMID: 23449393
    10. TTR blocks the ability of holo-retinol-binding protein to associate with STRA6 and thereby effectively suppresses both STRA6-mediated retinol uptake and STRA6-initiated cell signaling. PMID: 22826435
    11. The effects of vitamin A, retinoic acid, and polyinosinic acid:polycytidylic acid on the systemic antigen-specific antibody response in mice vaccinated with tetanus toxoids are reported. PMID: 22739370
    12. LRAT acts together with Cyp26A1, one of the enzymes that catalyze the degradation of retinoic acid, and possibly with STRA6, the recently identified cell surface receptor for retinol-RBP PMID: 18093970

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 組織特異性：
    Widely expressed in the embryo. Detected in adult in the retinal pigment epithelium in the eye. In the adult, is highly expressed in cells that compose blood-organ barriers in the brain (choroid plexus and the brain microvascular), in testis (the basal la
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 天天av天天翘天天综合网色鬼| 综合久久—本道中文字幕| 夜夜高潮夜夜爽高清视频| 国产精品久久久久久熟妇吹潮软件| 国产一区二区内射最近更新| 亚洲日本中文字幕天天更新| 欧美午夜一区二区福利视频| 中文字幕无码中文字幕有码| 国产综合有码无码视频在线| 亚洲日本精品国产一区vr| 国产精品久久久久久久久久红粉 | 女厕偷窥一区二区三区| 久久九九久精品国产| 日本高清在线天码一区播放| 亚洲日韩亚洲另类| 欧美老熟妇xb水多毛多| 久久综合色鬼综合色| 久久99亚洲含羞草影院| 亚洲人成77777在线播放网站不卡| 日本熟妇人妻xxxx| 激情毛片无码专区| 色一乱一伦一图一区二区精品| 中文字幕有码无码av| 私人毛片免费高清影视院| 中国性少妇内射xxxx狠干| 国产偷国产偷亚洲清高孕妇| 亚洲人成色77777| 欧美熟妇另类久久久久久多毛 | 国产aⅴ爽av久久久久久| 超碰成人人人做人人爽| 无码国内精品人妻少妇蜜桃视频| 亚洲欧洲成人av每日更新| 亚洲国产成人精品无码区宅男| 正在播放国产剧情亂倫| 老妇女性较大毛片| 亚洲最大成人一区久久久| 人妻换着玩又刺激又爽| 又色又爽又黄的视频网站| 中文字幕乱码一区av久久不卡| 国产午睡沙发被弄醒完整版| 黑人大荫道bbwbbb高潮潮喷|