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  4. Recombinant Mouse Solute carrier family 2, facilitated glucose transporter member 5 (Slc2a5), partial

Recombinant Mouse Solute carrier family 2, facilitated glucose transporter member 5 (Slc2a5), partial

  • 中文名稱：
    小鼠Slc2a5重組蛋白
  • 貨號：
    CSB-YP892997MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Slc2a5重組蛋白
  • 貨號：
    CSB-EP892997MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Slc2a5重組蛋白
  • 貨號：
    CSB-EP892997MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Slc2a5重組蛋白
  • 貨號：
    CSB-BP892997MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Slc2a5重組蛋白
  • 貨號：
    CSB-MP892997MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Slc2a5
  • Uniprot No.：
  • 別名：
    Slc2a5; Glut5; Solute carrier family 2; facilitated glucose transporter member 5; Fructose transporter; Glucose transporter type 5; small intestine; GLUT-5
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Functions as a fructose transporter that has only low activity with other monosaccharides. Can mediate the uptake of deoxyglucose, but with low efficiency. Essential for fructose uptake in the small intestine. Plays a role in the regulation of salt uptake and blood pressure in response to dietary fructose. Required for the development of high blood pressure in response to high dietary fructose intake.
  • 基因功能參考文獻：
    1. identified amino acid residues of GLUT5 that define its substrate specificity for glucose transporter 5 (GLUT5)-mediated fructose transport. PMID: 29259131
    2. GLUT5 activity contributes to antipsychotic-induced weight gain. PMID: 27056716
    3. Feedforward upregulation of fructolytic and gluconeogenic enzymes specifically requires GLUT5 and KHK and may proactively enhance the intestine's ability to process anticipated increases in dietary fructose concentrations. PMID: 26084694
    4. Significant levels of blood fructose are maintained independent of dietary fructose, KHK, and GLUT5, probably by endogenous synthesis of fructose. PMID: 26316589
    5. Fructose and GluT5 play an important role in regulating adipose differentiation. PMID: 22827929
    6. We conclude that Glut5 is not required for OHC motility or cochlear amplification. PMID: 18417103
    7. The essential role of chloride and fructose absorbing Slc2a5 is reported. PMID: 18496516
    8. mRNA expression of GLUT5 varied diurnally in the duodenum, jejunum and ileum mucosa. GLUT5 protein level varied diurnally in duodenum and jejunum, but not in the ileum. PMID: 19082670
    9. Slc2a5 (Glut5) is essential for the absorption of fructose in the intestine and generation of fructose-induced hypertension. PMID: 19091748

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  • 亞細胞定位：
    Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Cell membrane, sarcolemma.
  • 蛋白家族：
    Major facilitator superfamily, Sugar transporter (TC 2.A.1.1) family, Glucose transporter subfamily
  • 組織特異性：
    Detected at the apical membrane of villi in the jejunum. Detected in jejunum mucosa. Detected in epididymis and whole testis (at protein level). Detected in small intestine, kidney and testis. Detected in cochlea, but not in inner or outer cochlear hair c
  • 數據庫鏈接：


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