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  4. Recombinant Mouse Solute carrier family 13 member 2 (Slc13a2), partial

Recombinant Mouse Solute carrier family 13 member 2 (Slc13a2), partial

  • 中文名稱：
    小鼠Slc13a2重組蛋白
  • 貨號：
    CSB-YP861703MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Slc13a2重組蛋白
  • 貨號：
    CSB-EP861703MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Slc13a2重組蛋白
  • 貨號：
    CSB-EP861703MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Slc13a2重組蛋白
  • 貨號：
    CSB-BP861703MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Slc13a2重組蛋白
  • 貨號：
    CSB-MP861703MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Slc13a2
  • Uniprot No.：
  • 別名：
    Slc13a2; Nadc1; Sdct1; Solute carrier family 13 member 2; Na(+)/dicarboxylate cotransporter 1; NaDC-1; Renal sodium/dicarboxylate cotransporter
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Cotransport of sodium ions and dicarboxylates such as succinate and citrate.
  • 基因功能參考文獻：
    1. Slc26a6-null mice exhibit increased renal and intestinal sodium-dependent succinate uptake, as well as urinary hyperoxaluria and hypocitraturia, but no change in urinary pH, indicating enhanced transport activity of NaDC-1. PMID: 23833257
    2. The acid-activated pathway mediating stimulation of kidney NaDC-1 activity requires a functional ET(B) receptor in vivo and in vitro. PMID: 20703215
    3. Substrate-dependent inward currents, measured using two-electrode voltage clamp, were similar for glutarate & succinate in Xenopus oocytes expressing mouse NaDC1. Currents evoked by glutarate in rabbit NaDC1 were about 5% of succinate-dependent currents. PMID: 16475819
    4. Sodium dicarboxylate cotransporter is involved in regulating levels of various Krebs cycle intermediates in the kidney, although impaired uptake of these intermediates does not significantly affect renal function under normal or ischemic stress. PMID: 17410095
  • 亞細胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    SLC13A/DASS transporter (TC 2.A.47) family, NADC subfamily
  • 組織特異性：
    Highly expressed in kidney and small intestine. Not detectable in brain, heart, stomach and skeletal muscle.
  • 數據庫鏈接：


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