在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Sodium bicarbonate transporter-like protein 11 (Slc4a11), partial

Recombinant Mouse Sodium bicarbonate transporter-like protein 11 (Slc4a11), partial

  • 中文名稱：
    小鼠Slc4a11重組蛋白
  • 貨號：
    CSB-YP021665MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Slc4a11重組蛋白
  • 貨號：
    CSB-EP021665MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Slc4a11重組蛋白
  • 貨號：
    CSB-EP021665MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Slc4a11重組蛋白
  • 貨號：
    CSB-BP021665MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Slc4a11重組蛋白
  • 貨號：
    CSB-MP021665MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Slc4a11
  • Uniprot No.：
  • 別名：
    Slc4a11; BTR1; Sodium bicarbonate transporter-like protein 11; Bicarbonate transporter-related protein 1; Sodium borate cotransporter 1; NaBC1; Solute carrier family 4 member 11
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Multifunctional transporter with an impact in cell morphology and differentiation. In the presence of borate B(OH)4(-), acts as a voltage-dependent electrogenic Na(+)-coupled B(OH)4(-) cotransporter controlling boron homeostasis. At early stages of stem cell differentiation, participates in synergy with ITGA5-ITGB1 and ITGAV-ITGB3 integrins and BMPR1A to promote cell adhesion and contractility that drives differentiation toward osteogenic commitment while inhibiting adipogenesis. In the absence of B(OH)4(-), acts as a Na(+)-coupled OH(-) or H(+) permeable channel with implications in cellular redox balance. Regulates the oxidative stress response in corneal endothelium by enhancing antioxidant defenses and protecting cells from reactive oxygen species. In response to hypo-osmotic challenge, also acts as water permeable channel at the basolateral cell membrane of corneal endothelial cells and facilitates transendothelial fluid reabsorption in the aqueous humor. In the presence of ammonia, acts as an electrogenic NH3/H(+) cotransporter and may play a role in ammonia transport and reabsorption in renal Henle's loop epithelium.
  • 基因功能參考文獻：
    1. Results provide evidence for a critical role of Vps35 in mouse corneal dystrophy; suggest that SLC4A11 appears to be a Vps35/retromer cargo, and Vps35-regulation of SLC4A11 trafficking may underlie Vps35/retromer regulation of corneal dystrophy. PMID: 28934248
    2. the declined tumor cell survival following inhibition of BCT could be the consequence of interplay of several inter-connected regulatory molecular events. PMID: 25123669
    3. Data shows that the function of SLCA11 is to facilitate the movement of water across the basolateral corneal epithelium. PMID: 23813972
    4. Successful knockout of the Slc4a11 gene was confirmed by immunohistochemistry and RT-PCR. Slit-lamp photography and AS-OCT showed progressive corneal edema. PMID: 23942972
    5. Loss of SLC4A11 leads to morphological changes in the fibrocytes and deafness. PMID: 20185830
    6. Results demonstrate the importance of NaBC1 in the audio-vestibular system and provide support for the hypothesis that SLC4A11 should be considered a potential candidate gene in patients with isolated sensorineural vestibular hearing abnormalities. PMID: 19586905

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Anion exchanger (TC 2.A.31) family
  • 組織特異性：
    Expressed in the endothelial cells of the cornea. In the inner ear, is located in fibrocytes underlying the stria vascularis. In the kidney, is expressed in the thin descending limb of Henle loop.
  • 數據庫鏈接：


主站蜘蛛池模板： 高清性欧美暴力猛交| 无码av大香线蕉| 日韩人妻无码一区二区三区久久99| 国内揄拍国内精品人妻浪潮av| 无码精品人妻一区二区三区98| 99久久国产综合精品成人影院| 亚洲色成人网站www永久四虎 | 国产高清视频一区三区| 在线观看成人年视频免费| 国产老熟女狂叫对白| www插插插无码免费视频网站| 日本特黄特色特爽大片| 香港特级三a毛片免费观看| 亚州中文字幕午夜福利电影| 又色又爽又黄的视频软件app| 无码日本精品xxxxxxxxx| 国产高清不卡免费视频| 丁香婷婷综合激情五月色| 在厨房被c到高潮a毛片奶水| 青草青草久热国产精品| 2021在线不卡国产麻豆| 亚洲五月天综合| 亚欧成a人无码精品va片| 国产欧美综合在线观看第十页 | 国产精品美女久久久久久2021| 人妻少妇乱子伦精品无码专区电影| 又大又长粗又爽又黄少妇视频| 国内精品九九久久久精品| 中文日产幕无线码6区收藏| 丰满人妻中伦妇伦精品app| 美女裸体十八禁免费网站| 亚洲日韩色在线影院性色| 又黄又爽又色视频| 亚洲成av人在线视| 最新的国产成人精品2022| 人妻无码中字在线a| 中文无码一区二区不卡αv| 蜜臀av99无码精品国产专区| 无码人妻精品一区二区三区下载| 狂野欧美性猛交xxxx| 精品视频一区二区三三区四区|