在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Serine/threonine-protein kinase ULK2 (Ulk2), partial

  • 中文名稱:
    小鼠Ulk2重組蛋白
  • 貨號:
    CSB-YP882556MO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Ulk2重組蛋白
  • 貨號:
    CSB-EP882556MO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Ulk2重組蛋白
  • 貨號:
    CSB-EP882556MO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Ulk2重組蛋白
  • 貨號:
    CSB-BP882556MO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Ulk2重組蛋白
  • 貨號:
    CSB-MP882556MO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Ulk2; Kiaa0623; Serine/threonine-protein kinase ULK2; EC 2.7.11.1; Serine/threonine-protein kinase Unc51.2; Unc-51-like kinase 2
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and a negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK, also acts as a negative regulator of AMPK through phosphorylation of the AMPK subunits PRKAA1, PRKAB2 and PRKAG1. May phosphorylate ATG13/KIAA0652, FRS2, FRS3 and RPTOR; however such data need additional evidences. Not involved in ammonia-induced autophagy or in autophagic response of cerebellar granule neurons (CGN) to low potassium concentration. Plays a role early in neuronal differentiation and is required for granule cell axon formation: may govern axon formation via Ras-like GTPase signaling and through regulation of the Rab5-mediated endocytic pathways within developing axons.
  • 基因功能參考文獻:
    1. ULK2 induced autophagy and inhibited growth in Ras-transformed immortalized Baby Mouse Kidney (iBMK) ATG5(+/+) but not in autophagy-deficient ATG5(-/-) cells. PMID: 24923441
    2. Ulk1 knockdown reduced fatty acid oxidation and enhanced fatty acid uptake, the metabolic changes that could contribute to adipogenesis, whereas Ulk2 knockdown had opposing effects. PMID: 24135897
    3. ULK2, by interaction with FRS2/3 and inhibition of SynGAP, functions to negatively regulate tyrosyl phosphorylation of signaling proteins downstream of FGFR1. PMID: 16887332
    4. ULK2 is localized to vesicular structures in growth cones of spinal ganglia afferent neurons. RNAi-mediated knockdown of ULK2 resulted in impaired endocytosis of nerve growth factor, excessive axon arborization, and severely stunted axon elongation. PMID: 17389358
  • 亞細胞定位:
    Cytoplasmic vesicle membrane; Peripheral membrane protein. Note=Localizes to pre-autophagosomal membrane.
  • 蛋白家族:
    Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:


主站蜘蛛池模板: 无码人妻精品一区二区三| 丰满人妻在公车被猛烈进入电影| 澳门永久av免费网站| 日本免费人成视频播放| 久久无码人妻国产一区二区| 国产精品青草久久久久福利99| 成在线人视频免费视频| 国产精品久久久亚洲| 色 成人 亚洲| 亚洲色成人影院在线观看| 精品无人区无码乱码毛片国产| 韩国精品一区二区无码视频| 国产午夜亚洲精品区| 色婷婷狠狠97成为人免费| 国产成人精品a视频免费福利| 四虎成人精品在永久免费| 免费无码av一区二区| 永久免费毛片在线播放| 午夜福利精品导航凹凸| 好爽别插了无码视频| 色哟哟在线视频精品一区| 日韩无套内射高潮| 亚洲精品成a人在线观看| 色偷偷88888欧美精品久久久| 免费无遮挡禁18污污网站| 国产成人18黄网站在线观看| 国产亚洲精品久久久久丝瓜 | 真人一进一出120秒试看| 国产久久精品| 中字幕人妻一区二区三区| a毛看片免费观看视频| 一本色道久久88精品综合| 大地资源中文第三页| 无码精品人妻一区二区三区人妻斩 | 天天躁日日躁狠狠躁欧美老妇小说| 国产艳妇av在线出轨| 日韩高清在线观看永久| 中文人妻熟女乱又乱精品| 少妇无码av无码专区线| 玩肥熟老妇bbw视频| 久久久精品一区aaa片|