在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Serine/threonine-protein kinase SMG1 (Smg1), partial

Recombinant Mouse Serine/threonine-protein kinase SMG1 (Smg1), partial

  • 中文名稱：
    小鼠Smg1重組蛋白
  • 貨號：
    CSB-YP803895MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Smg1重組蛋白
  • 貨號：
    CSB-EP803895MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Smg1重組蛋白
  • 貨號：
    CSB-EP803895MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Smg1重組蛋白
  • 貨號：
    CSB-BP803895MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Smg1重組蛋白
  • 貨號：
    CSB-MP803895MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Smg1
  • Uniprot No.：
  • 別名：
    Smg1; Kiaa0421; Serine/threonine-protein kinase SMG1; SMG-1; EC 2.7.11.1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Serine/threonine protein kinase involved in both mRNA surveillance and genotoxic stress response pathways. Recognizes the substrate consensus sequence [ST]-Q. Plays a central role in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating UPF1/RENT1. Recruited by release factors to stalled ribosomes together with SMG8 and SMG9 (forming the SMG1C protein kinase complex), and UPF1 to form the transient SURF (SMG1-UPF1-eRF1-eRF3) complex. In EJC-dependent NMD, the SURF complex associates with the exon junction complex (EJC) through UPF2 and allows the formation of an UPF1-UPF2-UPF3 surveillance complex which is believed to activate NMD. Also acts as a genotoxic stress-activated protein kinase that displays some functional overlap with ATM. Can phosphorylate p53/TP53 and is required for optimal p53/TP53 activation after cellular exposure to genotoxic stress. Its depletion leads to spontaneous DNA damage and increased sensitivity to ionizing radiation (IR). May activate PRKCI but not PRKCZ.
  • 基因功能參考文獻(xiàn)：
    1. smg-1 mutations confer strong hyper-sensitivity to IR. SMG-1 does not appear to act in any of the three major pathways known to mend DNA DSBs. PMID: 28634159
    2. Results demonstrate a critical role for Smg1 in early mouse development and link the loss of this NMD factor to major and widespread changes in the mammalian transcriptome. PMID: 20566848
  • 亞細(xì)胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    PI3/PI4-kinase family
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 久久精品国产99精品国产亚洲性色| 性欧美大胆免费播放| 乱人伦人妻精品一区二区| 风韵丰满熟妇啪啪区老熟熟女| 欧美人与物videos另类xxxxx| 性xxxxx大片免费视频| 综合久久国产九一剧情麻豆| 人妻洗澡被强公日日澡| 人妻熟女av一区二区三区| 午夜免费无码福利视频| 成人无码视频免费播放| 免费观看性欧美大片无片| 久久婷婷国产综合精品| 国产一区二区三区影院| 国精产品999一区二区三区有限| 四虎国产精品永久在线无码| 已婚少妇美妙人妻系列| 国产97在线 | 亚洲| 无码人妻精品一区二区三 | 日韩免费无码一区二区视频| 蜜臀av国产一区二区三区| 亚洲欧美国产国产一区二区三区| 成人国产精品秘片多多| 亚洲成a人片在线观看无码| 国产美女极度色诱视频www| 老妇高潮潮喷到猛进猛出| 18禁真人抽搐一进一出在线| 肉体裸交137日本大胆摄影| 精品97国产免费人成视频 | 97视频在线观看播放| 夫前人妻被灌醉侵犯在线| 国产 中文 制服丝袜 另类| 男女一边摸一边做爽爽| 国产动作大片中文字幕| 精品久久久久久777米琪桃花 | 国语精品一区二区三区| 98视频精品全部国产| 国内精品无码一区二区三区| 亚洲人成人77777网站| 深夜福利在线观看视频| 久久人人爽人人爽人人爽|