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  4. Recombinant Mouse Serine/threonine-protein kinase D3 (Prkd3), partial

Recombinant Mouse Serine/threonine-protein kinase D3 (Prkd3), partial

  • 中文名稱：
    小鼠Prkd3重組蛋白
  • 貨號：
    CSB-YP815650MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Prkd3重組蛋白
  • 貨號：
    CSB-EP815650MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Prkd3重組蛋白
  • 貨號：
    CSB-EP815650MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Prkd3重組蛋白
  • 貨號：
    CSB-BP815650MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Prkd3重組蛋白
  • 貨號：
    CSB-MP815650MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Prkd3; PrkcnSerine/threonine-protein kinase D3; EC 2.7.11.13; Protein kinase C nu type; nPKC-nu
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress.
  • 基因功能參考文獻：
    1. These data provide new insights of a specific PKD3 signaling pathway by identifying a new function, which has not been identified before. PMID: 27245420
    2. Erythropoietin regulates GATA1 through protein kinase D activation, promoting histone deacetylase 5 dissociation from GATA1, and subsequent GATA1 acetylation. PMID: 22983445
    3. These data validate PKD3 as a promising therapeutic target in prostate cancer and shed light on the role of secreted tumor-promoting factors in prostate cancer progression. PMID: 22532599
    4. PKCnu is an important component of signaling pathways downstream from novel PKC enzymes after B-cell receptor engagement PMID: 12506120
    5. the catalytic activity of PKD3 may regulate its nuclear import through autophosphorylation and/or interaction with another protein PMID: 16380377
    6. PKD3 is increasingly expressed in neuronal as well as in the supporting connective tissue and in skeletal muscles PMID: 18439271
    7. reveal a novel distinction between the exocrine and endocrine cells of the pancreas and further identify PKD3 as a signaling molecule that promotes hormone-stimulated amylase secretion PMID: 19028687

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  • 亞細胞定位：
    Cytoplasm. Membrane.
  • 蛋白家族：
    Protein kinase superfamily, CAMK Ser/Thr protein kinase family, PKD subfamily
  • 數據庫鏈接：


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