在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Septin-7 (Sept7)

  • 中文名稱:
    小鼠Sept7重組蛋白
  • 貨號:
    CSB-YP021030MO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Sept7重組蛋白
  • 貨號:
    CSB-EP021030MO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Sept7重組蛋白
  • 貨號:
    CSB-EP021030MO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Sept7重組蛋白
  • 貨號:
    CSB-BP021030MO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Sept7重組蛋白
  • 貨號:
    CSB-MP021030MO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Sept7
  • Uniprot No.:
  • 別名:
    Septin7; Cdc10; Sept7; Septin-7; CDC10 protein homolog
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length of Mature Protein
  • 表達區域:
    2-436
  • 氨基酸序列
    SVSARSAAA EERSVNCGTM AQPKNLEGYV GFANLPNQVY RKSVKRGFEF TLMVVGESGL GKSTLINSLF LTDLYSPEYP GPSHRIKKTV QVEQSKVLIK EGGVQLLLTI VDTPGFGDAV DNSNCWQPVI DYIDSKFEDY LNAESRVNRR QMPDNRVQCC LYFIAPSGHG LKPLDIEFMK RLHEKVNIIP LIAKADTLTP EECQQFKKQI MKEIQEHKIK IYEFPETDDE EENKLVKKIK DRLPLAVVGS NTIIEVNGKR VRGRQYPWGV AEVENGEHCD FTILRNMLIR THMQDLKDVT NNVHYENYRS RKLAAVTYNG VDNNKNKGQL TKSPLAQMEE ERREHVAKMK KMEMEMEQVF EMKVKEKVQK LKDSEAELQR RHEQMKKNLE AQHKELEEKR RQFEEEKANW EAQQRILEQQ NSSRTLEKNK KKGKIF
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation.
  • 基因功能參考文獻:
    1. SEPT7 regulates gross morphogenesis of the inner ear and maintains the size of the inner ear sensory epithelial area. It does not affect differentiation of hair cells and supporting cells. It exerts its effects at an early developmental stage of the inner ear. PMID: 27634570
    2. Sept7-deficient T cells failed to complete cytokinesis when prompted by pharmacological activation or cytokines. In contrast, cell division was not dependent on sept7 when cell-cell contacts, such as those with antigen-presenting cells, provided a niche. PMID: 26692174
    3. We identified stathmin as a key molecule aiding in septin-independent cytokinesis, demonstrated that stathmin supplementation is sufficient to override cytokinesis failure in SEPT7-null fibroblasts PMID: 25122120
    4. Sept7 provides a physical scaffold for HDAC6 to achieve efficient microtubule deacetylation, thereby negatively regulating microtubule stability to an optimal level for neuritogenesis. PMID: 24113571
    5. Septin 7 may regulate meiotic cell cycle progression by affecting microtubule cytoskeletal dynamics in mouse oocytes. PMID: 22895176
    6. Report SEPT4/5/7 expression in mouse cochlea and roles in auditory function. PMID: 22575789
    7. performed large-scale interaction screens to understand the neuronal functions of the ERK3/MK5 pathway and identified septin7 (Sept7) as a novel interacting partner of ERK3 PMID: 22508986
    8. In Sept9 knockout cells, long septin filaments stained for Sept7 disappeared. Instead, staining was found in short, often curved filaments and rings. Furthermore, Sept7 was no longer localized to the mitotic spindle PMID: 21824004
    9. SEPT7 is involved in the regulation of subcellular-compartment formation during spermiogenesis in the mouse. PMID: 20352323

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cleavage furrow. Midbody. Cytoplasm, cytoskeleton, cilium axoneme. Cell projection, cilium, flagellum.
  • 蛋白家族:
    TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, Septin GTPase family
  • 組織特異性:
    Expressed in the cerebral cortex (at protein level).
  • 數據庫鏈接:


主站蜘蛛池模板: 四房播播开心五月| 三上悠亚的av片在线无码| 亚洲精品电影院| 一本之道高清乱码久久久| 国产日产欧产美韩系列麻豆| 色综合天天综合欧美综合| 久久国产亚洲精品无码| 少妇高潮av久久久久久| 中文字幕无线码一区二区| 成年无码动漫av片在线观看羞羞| 国产传媒麻豆剧精品av国产 | 人妻av中文字幕久久| 亚洲日韩av一区二区三区四区 | 一个人看的日本hd免费| 久久精品中文騷妇女内射| 久久99精品国产自在现线小黄鸭| 大屁股国产白浆一二区| 国产成人综合久久免费导航| 又色又爽又黄的视频软件app| 爽爽精品dvd蜜桃成熟时电影院| 国产又黄又爽又色的免费| 久久99精品久久久久久2021 | 日产精品一卡2卡三卡4乱码| 少妇性荡欲午夜性开放视频剧场| 少妇下面好紧好多水真爽播放| 亚洲人成网站观看在线播放| 伊人久久大香线蕉av综合| 国产精品人妻一码二码| 国产美女精品一区二区三区| 亚洲性无码av中文字幕| 亚洲欧洲免费三级网站| 国产 | 欧洲野花视频天堂视频p| 国产在线国偷精品产拍| 欧洲熟妇色xxxx欧美老妇| 99国产欧美另类久久久精品| 麻豆国产成人av高清在线观看| 成人影院yy111111在线观看| 最近中文字幕mv在线资源| 永久黄网站免费视频性色| 成人欧美一区二区三区视频| 6699嫩草久久久精品影院|