在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse SH2 domain-containing protein 2A (Sh2d2a)

  • 中文名稱:
    小鼠Sh2d2a重組蛋白
  • 貨號:
    CSB-YP868766MO
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Sh2d2a重組蛋白
  • 貨號:
    CSB-EP868766MO
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Sh2d2a重組蛋白
  • 貨號:
    CSB-EP868766MO-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Sh2d2a重組蛋白
  • 貨號:
    CSB-BP868766MO
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Sh2d2a重組蛋白
  • 貨號:
    CSB-MP868766MO
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Sh2d2a; Lad; Ribp; SH2 domain-containing protein 2A; Lck-associated adapter protein; Lad; Rlk/Itk-binding protein; Ribp
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達(dá)區(qū)域:
    1-374
  • 氨基酸序列
    MEFCLAQPCP QGNHEATSST FNTFQPMNLT QGRCQNLSCG SRPSMQVMKE QGVQLSPRTN HTVVSASAPG TAWVLGNADR AEEVPGKGDL SLQAETRAWV QKTQAHWLLL KTAPLWFHGF ITRREAERLL QPQPLGCYLV RFSESAVTFV LSYRSQTCCR HFLLAQLGDG RHVVLGEDSA HAQLQDLLEH YTECPLSPYG EILTQPLARQ TAEPAGLSLR ADSDSGSKRQ DPDTQLSLLL QQGQAQASGH TEKVWASQQK ATSQASRPRP PIPAKPQLPP EVYTSPASRL HQAPPINPIY QEPDEPIAFY AMGRGSPGDA PSNIYAEVEG PSGTAPIGHP ILRKCWSRPI SRGQVREVQG KISSRSRAER GSPS
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Could be a T-cell-specific adapter protein involved in the control of T-cell activation. May play a role in p56-LCK-mediated T-cell signaling. Could be involved in the regulation of responses to T-cell activation stimuli, specifically proliferation and lymphokine production. Interactions with ITK and TXK may provide important biochemical links of these two important kinases with other components in the T-cell activation machinery.
  • 基因功能參考文獻(xiàn):
    1. Sh2d2a protein deficient mice display reduced clearance of Dm157 MCMV infection in the spleen. PMID: 25783199
    2. The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192. PMID: 25492967
    3. Results suggest a modulatory role for T cell specific adapter protein SH2D2A in T cell mediated immune surveillance of cancer. PMID: 23144743
    4. results show that TSAd, particularly the SH2 domain of TSAd, is essential for the effector functions of T cells. PMID: 19756394
    5. role of TSAd as a critical regulator of T cell death whose absence promotes systemic autoimmunity PMID: 12953096
    6. TSAd appears to contribute to interleukin-2 synthesis at multiple different levels PMID: 15752554
    7. The major role of T cell-specific adapter protein in peripheral T cell cytoplasm is for activation of LCK protein tyrosine kinase at the outset of T cell receptor signal transduction PMID: 16446380
    8. Although Rlk/Itk-binding protein (RIBP) is coexpressed with related adaptor lymphocytes of unknown function X (ALX) protein on both T- and B-lymphocytes during cell development, no redundancy or synergy is found. PMID: 17641043

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm. Cell membrane. Note=Redistributed from cytoplasm to the plasma membrane in a T-cell activation-dependent manner.
  • 組織特異性:
    Expression limited to tissues of the immune system and, in particular, activated T-cells and natural killer cells. Expressed in the thymus, lymph node, and to a lesser extent, in the spleen and bone marrow. According to PubMed:10553045, also expressed in
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 麻豆精产国品| 2018天天躁夜夜躁狠狠躁| 免费女人裸体视频无遮挡免费网站 | 国产一卡二卡三卡四卡视频版| 久久精品久久精品久久39| 丰满人妻被中出中文字幕| 国产精品青青在线观看爽香蕉 | 亚洲女人色综合小说| 成人亚洲a片v一区二区三区动漫| 久久婷婷成人综合色综合| 成熟丰满熟妇av无码区| 天堂网在线最新版www中文网| 狠狠色狠狠色综合网老熟女| 五月婷婷久久草| 999久久久免费精品国产| av老司机亚洲精品天堂| 少妇性l交大片7724com | 国产女人天天春夜夜春| 内射女校花一区二区三区| 欧美一区二区三区成人久久片| 亚洲天堂2017无码中文| 久久99国产综合精品女同| 国产成人精品手机在线观看| 中文字幕亚洲欧美日韩在线不卡| 极品尤物被啪到呻吟喷水| 亚洲成色最大综合在线| 曰批全过程免费视频观看软件潮喷 | 狠狠色综合7777久夜色撩人ⅰ | 亚洲欧洲自拍拍偷综合| 露脸内射熟女--69xx| 99亚洲男女激情在线观看| 中文乱码字幕视频观看网站免费| 国产精品美女久久久久久2021| 深爱婷婷国产在线精品av| 成人天堂资源www在线| 成在人线av无码免观看麻豆| 久久国产欧美成人av| 亚洲精品久久久久avwww潮水| 丰满人妻熟妇乱偷人无码| 精品国产综合成人亚洲区| 国产成人亚洲精品无码车a |