在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse SH2 domain-containing protein 2A (Sh2d2a)

  • 中文名稱:
    小鼠Sh2d2a重組蛋白
  • 貨號:
    CSB-YP868766MO
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Sh2d2a重組蛋白
  • 貨號:
    CSB-EP868766MO
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Sh2d2a重組蛋白
  • 貨號:
    CSB-EP868766MO-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Sh2d2a重組蛋白
  • 貨號:
    CSB-BP868766MO
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Sh2d2a重組蛋白
  • 貨號:
    CSB-MP868766MO
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Sh2d2a; Lad; Ribp; SH2 domain-containing protein 2A; Lck-associated adapter protein; Lad; Rlk/Itk-binding protein; Ribp
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達(dá)區(qū)域:
    1-374
  • 氨基酸序列
    MEFCLAQPCP QGNHEATSST FNTFQPMNLT QGRCQNLSCG SRPSMQVMKE QGVQLSPRTN HTVVSASAPG TAWVLGNADR AEEVPGKGDL SLQAETRAWV QKTQAHWLLL KTAPLWFHGF ITRREAERLL QPQPLGCYLV RFSESAVTFV LSYRSQTCCR HFLLAQLGDG RHVVLGEDSA HAQLQDLLEH YTECPLSPYG EILTQPLARQ TAEPAGLSLR ADSDSGSKRQ DPDTQLSLLL QQGQAQASGH TEKVWASQQK ATSQASRPRP PIPAKPQLPP EVYTSPASRL HQAPPINPIY QEPDEPIAFY AMGRGSPGDA PSNIYAEVEG PSGTAPIGHP ILRKCWSRPI SRGQVREVQG KISSRSRAER GSPS
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能:
    Could be a T-cell-specific adapter protein involved in the control of T-cell activation. May play a role in p56-LCK-mediated T-cell signaling. Could be involved in the regulation of responses to T-cell activation stimuli, specifically proliferation and lymphokine production. Interactions with ITK and TXK may provide important biochemical links of these two important kinases with other components in the T-cell activation machinery.
  • 基因功能參考文獻(xiàn):
    1. Sh2d2a protein deficient mice display reduced clearance of Dm157 MCMV infection in the spleen. PMID: 25783199
    2. The kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192. PMID: 25492967
    3. Results suggest a modulatory role for T cell specific adapter protein SH2D2A in T cell mediated immune surveillance of cancer. PMID: 23144743
    4. results show that TSAd, particularly the SH2 domain of TSAd, is essential for the effector functions of T cells. PMID: 19756394
    5. role of TSAd as a critical regulator of T cell death whose absence promotes systemic autoimmunity PMID: 12953096
    6. TSAd appears to contribute to interleukin-2 synthesis at multiple different levels PMID: 15752554
    7. The major role of T cell-specific adapter protein in peripheral T cell cytoplasm is for activation of LCK protein tyrosine kinase at the outset of T cell receptor signal transduction PMID: 16446380
    8. Although Rlk/Itk-binding protein (RIBP) is coexpressed with related adaptor lymphocytes of unknown function X (ALX) protein on both T- and B-lymphocytes during cell development, no redundancy or synergy is found. PMID: 17641043

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm. Cell membrane. Note=Redistributed from cytoplasm to the plasma membrane in a T-cell activation-dependent manner.
  • 組織特異性:
    Expression limited to tissues of the immune system and, in particular, activated T-cells and natural killer cells. Expressed in the thymus, lymph node, and to a lesser extent, in the spleen and bone marrow. According to PubMed:10553045, also expressed in
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 成人国产一区二区精品小说 | 久久人人97超碰a片精品| 国产 | 欧洲野花视频欧洲1| 欧洲人免费视频网站在线| 五月天天天综合精品无码| 少妇粉嫩小泬喷水视频www| 爆爽久久久一区二区又大又黄又嫩 | 国产无遮挡又黄又爽高潮| 精品少妇人妻av免费久久洗澡| 亚洲一区二区三区丝袜| 亚洲性夜夜天天天| 扒开双腿猛进入喷水高潮叫声| 成人免费无码视频在线网站| 免费网站观看www在线观看| 99久久99久久精品国产片| 白丝乳交内射一二三区| 国产精品无码永久免费888| 国产午夜精品久久久久免费视| 国产精品久久..4399| 99久久久无码国产精品动漫| 亚洲中字幕日产av片在线| 久久成人a毛片免费观看网站| 色窝窝无码一区二区三区| 国语自产拍精品香蕉在线播放 | 98久9在线 | 免费| 激情综合五月| 狠狠躁夜夜躁人人爽天天| 人妻无码手机在线中文| 亚洲日韩一区精品射精| 国产成人无码精品午夜福利a| 人人爽人人爽人人片av免费| 麻豆精品传媒一二三区艾秋| 精品人妻av区乱码| 国产精品点击进入在线影院高清| 高潮好爽视频在线观看| 亚洲精品无amm毛片| 男人添女人下部高潮视频| 亚洲欧美在线一区中文字幕| 国产乱人伦真实精品视频| 女性女同性aⅴ免费观女性恋| 国产精品亚洲片在线观看不卡 |