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  4. Recombinant Mouse SAM and SH3 domain-containing protein 3 (Sash3)

Recombinant Mouse SAM and SH3 domain-containing protein 3 (Sash3)

  • 中文名稱：
    小鼠Sash3重組蛋白
  • 貨號：
    CSB-YP814313MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Sash3重組蛋白
  • 貨號：
    CSB-EP814313MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Sash3重組蛋白
  • 貨號：
    CSB-EP814313MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Sash3重組蛋白
  • 貨號：
    CSB-BP814313MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Sash3重組蛋白
  • 貨號：
    CSB-MP814313MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Sash3
  • Uniprot No.：
  • 別名：
    Sash3; Sly; SAM and SH3 domain-containing protein 3; SH3 protein expressed in lymphocytes
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-380
  • 氨基酸序列
    MLRRKPSNAS DKEPTQKKKL SLQRSSSFKD FAKSKPSSPV VSEKEFNLDD NIPEDDSGVL TPEDSGKSGK KLGKKWRAVI SRTMNRKMGK MMVKALSEEM GDTLEEGSAS PTSPDCSLDS PGPEKMALAF TEQEEREPPS LSRQTSTGSE LCSPGPGSGS FLEESPAPQY TGPFCGRARV HTDFTPSPYD HDSLKLQKGD VIQIVEKPPV GTWLGLLNGK LGSFKFIYVD VLPEEAVGPV RPSRRQSKGK RPKPKTLHEL LERIGLEEHT STLLLNGYQT LEDFKELRET HLNELNIMDP QHRAKLLTAA ELLLDYDTGS EEAEEGAESS QEPVAHTVSE PKVDIPRDSG CFEGSESGRD EAELAGTEEQ LQGLSLSGAP
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    May function as a signaling adapter protein in lymphocytes.
  • 基因功能參考文獻：
    1. this study describes SLy1 as an immunoregulatory protein, which is involved in the generation of adaptive immune responses during L. monocytogenes infection, and provides a model of how SLy1 regulates T-cell proliferation. PMID: 26306874
    2. Sly1 is an essential molecular component for the full activation of adaptive immunity PMID: 16227612
    3. expression of the Notch signaling mediator RBP-J and the Notch target genes Hes-1 and Hes-5 was markedly reduced in MZ but not FO B cells of Sly1(d/d) mice. PMID: 18950867
    4. anti-apoptotic protein required for T cell differentiation to the CD4+CD8+ stage, likely to be involved in mTOR complex activation PMID: 19604361
  • 組織特異性：
    Preferentially expressed in lymphoid tissues. Expressed in bone marrow, thymus, spleen, lymph nodes and Peyer patches of gut. In the spleen and lymph nodes, expressed in both T- and B-cells. In the thymus, in the medulla and cortex.
  • 數據庫鏈接：


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