在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Rho GTPase-activating protein 7 (Dlc1), partial

Recombinant Mouse Rho GTPase-activating protein 7 (Dlc1), partial

  • 中文名稱：
    小鼠Dlc1重組蛋白
  • 貨號：
    CSB-YP879500MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Dlc1重組蛋白
  • 貨號：
    CSB-EP879500MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Dlc1重組蛋白
  • 貨號：
    CSB-EP879500MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Dlc1重組蛋白
  • 貨號：
    CSB-BP879500MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Dlc1重組蛋白
  • 貨號：
    CSB-MP879500MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Dlc1
  • Uniprot No.：
  • 別名：
    Dlc1; Arhgap7; Stard12; Rho GTPase-activating protein 7; Deleted in liver cancer 1 protein homolog; DLC-1; Rho-type GTPase-activating protein 7; START domain-containing protein 12; StARD12; StAR-related lipid transfer protein 12
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.
  • 基因功能參考文獻：
    1. DLC-1 has a positive regulatory role in endothelial cell angiogenesis. PMID: 28408355
    2. Loss of expression of only Dlc1 isoform 2 may be sufficient for the development of thymic tumors and metastasis. PMID: 22792269
    3. Several genes and biochemical activities collaborate with the inactivation of DLC1 to give rise to cell transformation in MEFs, and the identified genes are relevant to human tumors with low DLC1 expression. PMID: 23010077
    4. The Dlc1 deficient cells showed altered cytoskeleton structure, increased RhoA activity and cellular migration. PMID: 20199662
    5. DLC-1-/- embryos had defects in the neural tube, brain, heart, and placenta PMID: 15710412
    6. Our data validate DLC1 as a potent tumor suppressor gene and suggest that its loss creates a dependence on the RhoA pathway that may be targeted therapeutically. PMID: 18519636

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cell junction, focal adhesion. Membrane; Peripheral membrane protein.
  • 組織特異性：
    Widely expressed with the highest levels in heart, liver and lung.
  • 數據庫鏈接：


主站蜘蛛池模板： 国产成人av男人的天堂| 国产69久久精品成人看| 免费观看的av在线播放| 正在播放国产真实哭都没用| 精品国产乱码久久久久久下载| 十八禁视频在线观看免费无码无遮挡骂过| 国产免费一区二区三区在线观看 | 青青草大香焦在线综合视频| av片在线观看免费| 久久精品国产亚洲a片高清不卡| 久久午夜色播影院| 大伊香蕉精品视频在线| 国产suv精品一区二区69| 国产av精国产传媒| 乱中年女人伦av二区 | 久久66热人妻偷产精品| 无码潮喷a片无码高潮视频| 亚洲色偷偷偷综合网| 无码人妻久久一区二区三区 | 亚洲热妇无码av在线播放| 中文无码天天av天天爽| 久久天天躁夜夜躁狠狠85麻豆| 天天躁日日躁狠狠躁| 麻豆专媒体一区二区| 狠狠做五月深爱婷婷伊人| 亚洲精品一区| 蜜臀av99无码精品国产专区| 国产偷国产偷亚洲清高网站| 久久亚洲国产成人精品无码区 | 日本无卡码高清免费v| 最新高清无码专区| 人妻夜夜爽天天爽| 亚洲无av码在线中文字幕| 国产精品日本亚洲777| 第九色区av天堂| 日韩人妻精品一区二区三区视频| 国产高清视频色拍| 国产成人精品aa毛片| 熟女少妇在线视频播放| 欧美婷婷六月丁香综合| 日本中文一区二区三区亚洲|