在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Regulator of G-protein signaling 7-binding protein (Rgs7bp)

Recombinant Mouse Regulator of G-protein signaling 7-binding protein (Rgs7bp)

  • 中文名稱：
    小鼠Rgs7bp重組蛋白
  • 貨號：
    CSB-YP806890MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Rgs7bp重組蛋白
  • 貨號：
    CSB-EP806890MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Rgs7bp重組蛋白
  • 貨號：
    CSB-EP806890MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Rgs7bp重組蛋白
  • 貨號：
    CSB-BP806890MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Rgs7bp重組蛋白
  • 貨號：
    CSB-MP806890MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Rgs7bp
  • Uniprot No.：
  • 別名：
    Rgs7bp; D13Bwg1146e; R7bp; Regulator of G-protein signaling 7-binding protein; R7 family-binding protein
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-257
  • 氨基酸序列
    MSSAPNGRKK RPSRSTRSSI FQISKPPLQS GDWERRGSGS ESAHKTQRAL DDCKMLVQEF NTQVALYREL VISIGDVSVS CPSLRAEMHK TRTKGCEMAR QAHQKLAAIS GPEDGEIHPE ICRLYIQLQC CLEMYTTEML KSICLLGSLQ FHRKGKEASG GAKNLDSKIE ENAETPALED SLSSPLESQQ QCWQVATDIE NTERDMREMK NLLSKLRETM PLPLKNQDDS SLLNLTPYPM VRRRKRRFFG LCCLVSS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Regulator of G protein-coupled receptor (GPCR) signaling. Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellular location of the R7-Gbeta5 complexes. When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits. When it is unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cytoplasmic shuttling. May also act by controlling the proteolytic stability of R7 proteins, probably by protecting them from degradation.
  • 基因功能參考文獻：
    1. The results of this study indicated that R7bp is a key regulator of itch sensation and suggest the potential targeting of R7bp-dependent GTPase activating protein activity as a novel therapeutic strategy for pathological itch PMID: 28134655
    2. R7BP-dependent regulation of R7-RGS proteins shapes specific aspects of light-evoked and spontaneous activity of retinal ganglion cells in mature and developing retina. PMID: 24349243
    3. GIRK modulation occurs by channel assembly with R7-RGS/Gbeta5 complexes under allosteric control of R7 RGS-binding protein (R7BP). PMID: 23169654
    4. R7BP is a negative modulator of the analgesic and locomotor activating actions of morphine that contributes to the development of morphine tolerance. PMID: 22089315
    5. regulator of G-protein signalling 7 binding protein contributes significantly to the nuclear localization of endogenous G beta(5)/R7-RGS complex in brain PMID: 20100282
    6. These results indicate that dopamine signaling in the striatum is controlled by concerted interplay between two RGS proteins, RGS7 and RGS9-2, which are balanced by a common subunit, R7BP. PMID: 20043004
    7. All four R7 RGS proteins co-precipitate with R7BP from brain extracts and recombinant R7 proteins bind recombinant R7BP with high efficiency PMID: 15632198
    8. Review. R7BP transduces signals directly from receptors and G proteins at the plasma membrane to the nucleus, and this plasma membrane-nuclear shuttling is controlled by reversible palmitoylation of R7BP. PMID: 16046666
    9. R7BP controls expression of regulator of G-protein signaling (RGS)9-2 expression at the posttranslational level. PMID: 18094251
    10. R7-Gbeta5-R7BP complexes in the mouse could regulate signaling by modulatory Gi/o-coupled GPCRs in the developing and adult nervous systems. PMID: 18248908
    11. Gbeta5 and R7BP in striatum undergo remodeling upon changes in neuronal activity. PMID: 19332565

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Cytoplasm. Cell membrane; Lipid-anchor.
  • 蛋白家族：
    RGS7BP/RGS9BP family
  • 組織特異性：
    Specifically expressed in the central nervous system including the retina but not in other non-neuronal tissues (at protein level).
  • 數據庫鏈接：


主站蜘蛛池模板： 曰批免费视频播放免费| 久青草国产97香蕉在线影院| 免费观看潮喷到高潮中文字幕| 97成人精品区在线播放| 99精品视频在线观看免费蜜桃| 精品一区二区三区无码av久久| 无遮挡裸体免费视频尤物| 亚欧美日韩香蕉在线播放视频| 五月激激激综合网亚洲| 九九99无码精品视频在线观看| 99久久99久久精品免费观看| 欧美黑人添添高潮a片www| 成在人线av无码免观看| 女人摸下面自熨视频在线播放| 疯狂三人交性欧美| 曰本女人与公拘交酡| 水蜜桃精品一二三| 人人妻人人爽人人添夜夜欢视频 | 日本边添边摸边做边爱| 国模冰莲极品自慰人体| 18禁无码永久免费无限制网站| 影音先锋中文无码一区| 亚洲国产美女精品久久久久| 50路60路老熟妇啪啪| 四虎永久在线高清国产精品| 亚洲精品午夜一区二区电影院| 日韩电影一区二区三区| 国产午夜福利片| 亚洲性无码av在线| 成人亚洲a片v一区二区三区动漫| 日本熟妇浓毛hdsex| 成年无码动漫av片在线观看羞羞| 亚洲人成手机电影网站| 国产人成无码视频在线观看| 欧美大屁股xxxx高跟欧美黑人| 女乱高潮久久久久久爽爽| 亚洲日韩精品国产一区二区三区 | 一日本道a高清免费播放| 人妻精品国产一区二区| 青椒国产97在线熟女| 国产精品人人妻人人爽人人牛|