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Recombinant Mouse Regulator of G-protein signaling 20 (Rgs20)

  • 中文名稱:
    小鼠Rgs20重組蛋白
  • 貨號(hào):
    CSB-YP019652MO
  • 說明書:
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Rgs20重組蛋白
  • 貨號(hào):
    CSB-EP019652MO
  • 說明書:
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Rgs20重組蛋白
  • 貨號(hào):
    CSB-EP019652MO-B
  • 說明書:
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Rgs20重組蛋白
  • 貨號(hào):
    CSB-BP019652MO
  • 說明書:
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Rgs20重組蛋白
  • 貨號(hào):
    CSB-MP019652MO
  • 說明書:
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Rgs20
  • Uniprot No.:
  • 別名:
    Rgs20; Rgsz1; Regulator of G-protein signaling 20; RGS20; Regulator of G-protein signaling Z1
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達(dá)區(qū)域:
    1-239
  • 氨基酸序列
    MRTANGGPRA RASPSASPAD PGLPEGSERT EMRMRQMCGG SETQGPAPSQ QGGRGSNACC FCWCCCCTCS CLTVRNQEDQ RPQRASHEIR TDIPACEESP TPTLEEVCAW AQSFDNLMVT PAGRNAFREF LRTEFSEENM LFWMACEELK REANKSTIEE KARIIYEDYI SILSPKEVSL DSRVREVINR NMVDPSQHIF DDAQLQIYTL MHRDSYPRFM NSTVYKDLLT SLAEKTVEA
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds selectively to G(z)-alpha and G(alpha)-i2 subunits, accelerates their GTPase activity and regulates their signaling activities. The G(z)-alpha activity is inhibited by the phosphorylation and palmitoylation of the G-protein. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins.
  • 基因功能參考文獻(xiàn):
    1. RGSz1 function suppression optimizes the actions of opioid analgesics by mechanisms that involve the Wnt/beta-catenin pathway PMID: 29440403
    2. Analysis of in vitro microtubule polymerization/depolymerization showed that binding of RGSZ1 to SCG10 effectively blocked the ability of SCG10 to induce microtubule disassembly PMID: 11882662
  • 亞細(xì)胞定位:
    Membrane; Lipid-anchor. Nucleus. Cytoplasm.
  • 數(shù)據(jù)庫鏈接:

    KEGG: mmu:58175

    UniGene: Mm.103771



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