在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Receptor-type tyrosine-protein phosphatase F (Ptprf), partial

Recombinant Mouse Receptor-type tyrosine-protein phosphatase F (Ptprf), partial

  • 中文名稱：
    小鼠Ptprf重組蛋白
  • 貨號：
    CSB-YP019053MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Ptprf重組蛋白
  • 貨號：
    CSB-EP019053MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Ptprf重組蛋白
  • 貨號：
    CSB-EP019053MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Ptprf重組蛋白
  • 貨號：
    CSB-BP019053MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Ptprf重組蛋白
  • 貨號：
    CSB-MP019053MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Ptprf; Lar; Receptor-type tyrosine-protein phosphatase F; EC 3.1.3.48; Leukocyte common antigen related; LAR
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity.
  • 基因功能參考文獻：
    1. loss of LAR activity resulted in reduced activity of CDK1. PMID: 27352860
    2. Study has identified LAR as a regulator of key signaling pathways, including mTOR and JNK, and has significantly expanded the number of proteins regulated downstream of LAR phosphatase activity. PMID: 27074791
    3. This study demonstrates the crucial role of LAR in restricting regrowth of injured CNS axons PMID: 25220840
    4. Ptprs and Ptprf deficiency affects mandibular cell proliferation. PMID: 23863482
    5. Inhibition of LAR attenuates palmitate-induced insulin resistance in myotubes. PMID: 22899729
    6. Deletion of LAR in knock-out mice or blockade of LAR with sequence-selective peptides significantly overcomes neurite growth restrictions of chondroitin sulfate proteoglycan in neuronal cultures. PMID: 21976490
    7. the crystal structures of the first and second immunoglobulin-like domains of the Drosophila type IIa receptor Dlar and its mouse homolog LAR were reported. PMID: 21402080
    8. LAR reduces the basal c-Abl activity thereby allowing for platelet derived growth factor beta receptor kinase activation PMID: 21300149
    9. LAR deficiency affected the differentiation & expansion of immature thymocytes, positive & negative selection, & a lower Ca2+ response. LAR is an important modulator of TCR signaling that controls thymocyte differentiation. PMID: 20186877
    10. LAR PTPase domains play distinct functional roles in phosphorylation and dephosphorylation PMID: 12496362
    11. PTP alpha is required for integrin-proximal events and phosphorylates FAK PMID: 12515828
    12. In conclusion, behavioural testing of the LAR tyrosine phosphatase-deficient mice revealed a spatial learning impairment and a significant increase in activity. PMID: 15302123
    13. LAR enhances retinal ganglion cell neurite initiation whilst suppressing retinal ganglion cell survival PMID: 15932596
    14. Results introduce leukocyte common antigen-related (LAR) protein tyrosine phosphatase (PTP) as the first PTP found to be expressed in dentate progenitors and point to inhibition of LAR as a potential strategy for promoting neurogenesis. PMID: 16488625
    15. Here, we report rapid and efficient construction of PTPRF and NWC TgVs without using restriction endonucleases. PMID: 17498650

    顯示更多

    收起更多

  • 亞細胞定位：
    Membrane; Single-pass membrane protein.
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Receptor class 2A subfamily
  • 組織特異性：
    Expressed in the cell of the T lineage but not in cells of any other hemopoietic lineage.
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲精品无码久久久久av麻豆 | 综合色区亚洲熟妇另类| 国产99视频精品免费视看9| 亚洲国产欧美日韩精品一区二区三区| 边喂奶边中出的人妻| 国产精品综合色区在线观看| 99久久免费国产精精品| 日日澡夜夜澡人人高潮| 日韩精品一区二区三区在线观看l 亚洲在av人极品无码 | 亚洲乱色熟女一区二区三区丝袜 | 精产国品一二三产区9977| 久久国产精品老女人| 草草地址线路①屁屁影院成人| 日韩一区二区三区无码影院| 五月色丁香婷婷网蜜臀av| 国产精品亚洲二区在线看 | 亚洲国产成人综合一区二区三区 | 国产无遮挡a片无码免费| 天堂久久天堂av色综合| 国产午夜福利久久精品| 国产精品久久久久9999赢消 | 日产精品久久久久久久蜜臀| 欧美人与动性xxxxx杂| 国产精品老熟女露脸视频| 18禁无遮挡羞羞污污污污网站 | 色婷婷久久综合中文久久蜜桃av| 亚洲国产精品成人精品无码区在线| 一线二线无人区乱码 | 丁香花在线影院观看在线播放| 又爽又黄无遮拦成人网站| 日韩欧美偷拍高跟鞋精品一区| 国产乱人伦中文无无码视频试看 | 国产精品成人久久电影| 色一情一乱一乱一区99av| 欧美18videosex性欧美黑吊| 亚洲日韩av在线观看| 激情亚洲一区国产精品| 野外被强j到高潮免费观看| 亚洲精品一区二三区不卡| 97影院理论片手机在线观看 | 亚洲日韩a∨无码久|