在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse RNA polymerase I-specific transcription initiation factor RRN3 (Rrn3)

  • 中文名稱:
    小鼠Rrn3重組蛋白
  • 貨號:
    CSB-YP020525MO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Rrn3重組蛋白
  • 貨號:
    CSB-EP020525MO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Rrn3重組蛋白
  • 貨號:
    CSB-EP020525MO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Rrn3重組蛋白
  • 貨號:
    CSB-BP020525MO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Rrn3重組蛋白
  • 貨號:
    CSB-MP020525MO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Rrn3
  • Uniprot No.:
  • 別名:
    Rrn3; RNA polymerase I-specific transcription initiation factor RRN3
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-656
  • 氨基酸序列
    MAAPLLHTRL SGDVTAAASA TLSASRTGLS DMLALESDFF NSPPKKTVRF GGTVTEVLLK YKKGETNDLE LLKNQLSDPD IKDDQIINWL LEFRSSVMYL TKDFEQLINI ILRLPWLNRS QRVVEEYLAF LGNLVSAQTV FLRPCLSMIA SHFVPPRVIV KEGGIDVSDS DDEDDNLPAI FDTCHRALQI ITRYVPSTPW FLMPILVEKF PFVRKSERTL ECYVHNLLRI SLYFPTLRRE ILELVIEKLL KLDVSVSRQD IEDAEEKAAQ TCGGTDTTEG LFNMDEDEDT DPEKKADQEQ PNQMAHPTAE RLDVLLCLLL SYIEDVCRVH GKIDNNKTKD LYRDLISIFD KLLLPTHASC HVQFFMFFLC SFKLGFAEAF LEHLWKKLQD PNNPAIIRQA AANYIGSFLA RAKFIPLITV KTCLDLLVNW LHMYLTNQDS GTKAFCDVAL HGPFYSACQA VFYTVVFRHK QLLSGNLKQG LQYLQSLNFE RIVLSQLNPL KICLPQVVNF FAAITNKYQL VFCYTIMERN SRQMLPVIRS TAGGDSVQTC TNPLDTFFPF DPCVLKRSKK FIDPIYQIWE DGSAEELQEF KKSTKKEVVE DEDDDFLKGE VPQSDTVTGL TPSSFDTHFQ SPSSSVGSPP VLYIPGQSPL LTRIYD
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent preinitiation complex (PIC). Dissociates from pol I as a consequence of transcription. In vitro, cannot activate transcription in a subsequent transcription reaction.
  • 基因功能參考文獻:
    1. Conditional deletion of the Rrn3 gene inhibits RNA polymerase I transcription but does not affect pre-initiation complex formation. PMID: 28715449
    2. The results exemplify how stress-induced inactivation of TIF-IA and long non-coding RNA -dependent changes of chromatin structure ensure repression of ribosomal RNA synthesis in response to thermo-stress. PMID: 27257073
    3. These data support a model in which activated Akt enhances rRNA synthesis both by preventing TIF-IA degradation and phosphorylating CK2alpha, which in turn phosphorylates TIF-IA. PMID: 24297901
    4. DNA binding by the ribosomal DNA transcription factor rrn3 is essential for ribosomal DNA transcription PMID: 23393135
    5. Ablation of TIF-IA leads to impaired nucleolar activity and results in increased levels of the proapoptotic transcription factor p53 in both neural progenitors and hippocampal neurons but induces rapid apoptosis only in neural progenitors. PMID: 19036968
    6. Rrn3 regulates rDNA transcription by determining the steady-state concentration of the Rrn3.RNA polymerase I complex within the nucleolus. (RRN3) PMID: 12015311
    7. ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth. PMID: 12620228
    8. Genetic inactivation of Tif1a leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis. PMID: 15989966

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus, nucleolus.
  • 蛋白家族:
    RRN3 family
  • 數據庫鏈接:


主站蜘蛛池模板: 日韩 高清 无码 人妻| 狠狠做深爱婷婷久久综合一区| 国产成人久久综合77777| 日韩国产精品人妻无码久久久| 毛片内射-百度| 内射无码专区久久亚洲| 天天摸日日摸狠狠添| 国产-第1页-浮力影院| 国产69精品久久久久久妇女迅雷| 日韩国产亚洲一区二区三区| 九九re6热在线视频精品66| 波多野美乳人妻hd电影欧美| 亚欧洲乱码视频一二三区| 真人性生交免费视频| 免费人成网站视频在线观看国内| 农村乱人伦一区二区| 农民人伦一区二区三区| 欧美午夜精品久久久久久浪潮| 亚洲 日本 欧美 中文字幕| 2021久久最新国产精品| 无码专区一va亚洲v专区在线 | 大肉大捧一进一出视频出来呀 | 黑色丝袜无码中中文字幕| 四虎影库在线永久影院免费观看| 狠狠色综合7777久夜色撩人| 国产精品成人片在线观看| 欧洲黑大粗无码免费| 国产情侣一区二区| 国产精品视频免费播放| 中文字幕久久久久人妻中出| 老湿机香蕉久久久久久| 99久久国产综合精品成人影院 | 国产精品多p对白交换绿帽| 国产男女猛烈视频在线观看| av小次郎收藏| 亚洲精品一区二区三区在线| 女人被男人桶30分钟无遮挡动态图| av综合网男人的天堂| 成人丝袜激情一区二区| 人妻丝袜中文无码av影音先锋专区 | 精品综合久久久久久888蜜芽|