在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse RNA polymerase I-specific transcription initiation factor RRN3 (Rrn3)

  • 中文名稱:
    小鼠Rrn3重組蛋白
  • 貨號:
    CSB-YP020525MO
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Rrn3重組蛋白
  • 貨號:
    CSB-EP020525MO
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Rrn3重組蛋白
  • 貨號:
    CSB-EP020525MO-B
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Rrn3重組蛋白
  • 貨號:
    CSB-BP020525MO
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Rrn3重組蛋白
  • 貨號:
    CSB-MP020525MO
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Rrn3
  • Uniprot No.:
  • 別名:
    Rrn3; RNA polymerase I-specific transcription initiation factor RRN3
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full length protein
  • 表達區域:
    1-656
  • 氨基酸序列
    MAAPLLHTRL SGDVTAAASA TLSASRTGLS DMLALESDFF NSPPKKTVRF GGTVTEVLLK YKKGETNDLE LLKNQLSDPD IKDDQIINWL LEFRSSVMYL TKDFEQLINI ILRLPWLNRS QRVVEEYLAF LGNLVSAQTV FLRPCLSMIA SHFVPPRVIV KEGGIDVSDS DDEDDNLPAI FDTCHRALQI ITRYVPSTPW FLMPILVEKF PFVRKSERTL ECYVHNLLRI SLYFPTLRRE ILELVIEKLL KLDVSVSRQD IEDAEEKAAQ TCGGTDTTEG LFNMDEDEDT DPEKKADQEQ PNQMAHPTAE RLDVLLCLLL SYIEDVCRVH GKIDNNKTKD LYRDLISIFD KLLLPTHASC HVQFFMFFLC SFKLGFAEAF LEHLWKKLQD PNNPAIIRQA AANYIGSFLA RAKFIPLITV KTCLDLLVNW LHMYLTNQDS GTKAFCDVAL HGPFYSACQA VFYTVVFRHK QLLSGNLKQG LQYLQSLNFE RIVLSQLNPL KICLPQVVNF FAAITNKYQL VFCYTIMERN SRQMLPVIRS TAGGDSVQTC TNPLDTFFPF DPCVLKRSKK FIDPIYQIWE DGSAEELQEF KKSTKKEVVE DEDDDFLKGE VPQSDTVTGL TPSSFDTHFQ SPSSSVGSPP VLYIPGQSPL LTRIYD
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Required for efficient transcription initiation by RNA polymerase I. Required for the formation of the competent preinitiation complex (PIC). Dissociates from pol I as a consequence of transcription. In vitro, cannot activate transcription in a subsequent transcription reaction.
  • 基因功能參考文獻:
    1. Conditional deletion of the Rrn3 gene inhibits RNA polymerase I transcription but does not affect pre-initiation complex formation. PMID: 28715449
    2. The results exemplify how stress-induced inactivation of TIF-IA and long non-coding RNA -dependent changes of chromatin structure ensure repression of ribosomal RNA synthesis in response to thermo-stress. PMID: 27257073
    3. These data support a model in which activated Akt enhances rRNA synthesis both by preventing TIF-IA degradation and phosphorylating CK2alpha, which in turn phosphorylates TIF-IA. PMID: 24297901
    4. DNA binding by the ribosomal DNA transcription factor rrn3 is essential for ribosomal DNA transcription PMID: 23393135
    5. Ablation of TIF-IA leads to impaired nucleolar activity and results in increased levels of the proapoptotic transcription factor p53 in both neural progenitors and hippocampal neurons but induces rapid apoptosis only in neural progenitors. PMID: 19036968
    6. Rrn3 regulates rDNA transcription by determining the steady-state concentration of the Rrn3.RNA polymerase I complex within the nucleolus. (RRN3) PMID: 12015311
    7. ERK-dependent phosphorylation of the transcription initiation factor TIF-IA is required for RNA polymerase I transcription and cell growth. PMID: 12620228
    8. Genetic inactivation of Tif1a leads to nucleolar disruption, cell cycle arrest, and p53-mediated apoptosis. PMID: 15989966

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus, nucleolus.
  • 蛋白家族:
    RRN3 family
  • 數據庫鏈接:


主站蜘蛛池模板: 国产精品igao视频网网址| 亚洲精品成人无码中文毛片| 国产又色又爽又刺激视频| 久久久久青草线蕉亚洲麻豆| 国产精品 自在自线| 国产制服丝袜亚洲高清| 狠狠色噜噜狠狠狠狠米奇777| 夜夜天天噜狠狠爱2019| 日韩免费无码专区精品观看| 大肉大捧一进一出好爽视色大师| 成人国产片女人爽到高潮| 熟妇好大好深好满好爽| 亚洲欧美丝袜精品久久| 日本亲近相奷中文字幕| 国产voyeur精品偷窥222| 伦理片午夜视频在线观看| 国产成+人欧美+综合在线观看| 久久精品一区二区av999| 国产成人精品视频ⅴa片软件竹菊 免费精品99久久国产综合精品 | 97免费人妻在线视频| 国产18禁黄网站免费观看| 亚洲精品www久久久| 国产欧美日韩综合精品二区| 国产精品视频白浆免费视频| 男人扒开女人双腿猛进视频| 国产亚洲精品久久yy5099| 无码中字出轨中文人妻中文中| 国产成人精品一区二区秒播| 群交射精白浆视频| 久久久www成人免费毛片| 肉感饱满中年熟妇日本| 国产午夜鲁丝片av无码免费| 欧美亚洲高清国产| 国产小呦泬泬99精品| 日本老妇人乱xxy| 亚洲一区天堂九一| 亚洲一二区制服无码中字 | 伊人久久成综合久久影院| 亚色九九九全国免费视频| 国产精品福利一区二区久久| 欧美日韩在线视频一区|