在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse RING finger protein 145 (Rnf145), partial

Recombinant Mouse RING finger protein 145 (Rnf145), partial

  • 中文名稱：
    小鼠Rnf145重組蛋白
  • 貨號：
    CSB-YP019842MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Rnf145重組蛋白
  • 貨號：
    CSB-EP019842MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Rnf145重組蛋白
  • 貨號：
    CSB-EP019842MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Rnf145重組蛋白
  • 貨號：
    CSB-BP019842MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Rnf145重組蛋白
  • 貨號：
    CSB-MP019842MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Rnf145
  • Uniprot No.：
  • 別名：
    Rnf145; RING finger protein 145; EC 2.3.2.27
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    E3 ubiquitin ligase that catalyzes the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific substrate. In response to bacterial infection, negatively regulates the phagocyte oxidative burst by controlling the turnover of the NADPH oxidase complex subunits. Promotes monoubiquitination of CYBA and 'Lys-48'-linked polyubiquitination and degradation of CYBB NADPH oxidase catalytic subunits, both essential for the generation of antimicrobial reactive oxygen species. Involved in the maintenance of cholesterol homeostasis. In response to high sterol concentrations ubiquitinates HMGCR, a rate-limiting enzyme in cholesterol biosynthesis, and targets it for degradation. The interaction with INSIG1 is required for this function. In addition, triggers ubiquitination of SCAP, likely inhibiting its transport to the Golgi apparatus and the subsequent processing/maturation of SREBPF2, ultimately downregulating cholesterol biosynthesis.
  • 基因功能參考文獻：
    1. Mechanistic studies show that RNF145 triggers ubiquitination of SCAP on lysine residues within a cytoplasmic loop essential for COPII binding, potentially inhibiting its transport to Golgi and subsequent processing of SREBP-2. PMID: 29068315
    2. we report the identification of RNF145 as an ER-resident E3 ubiquitin ligase that is transcriptionally controlled by LXR. PMID: 28231341
    3. implicated in proteostasis of Nox2 complex PMID: 26194095
  • 亞細胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 數據庫鏈接：


主站蜘蛛池模板： 97性无码区免费| 最新无码a∨在线观看| 琪琪秋霞午夜av影视在线| 国产成人精品无码一区二区三区 | 久久午夜夜伦鲁鲁片免费无码| 国产成人无码精品午夜福利a| 欧美成人看片一区二区| 人人人爽人人爽人人av| 欧美特级婬片毛多的少妇| 亚洲精品伊人久久久大香| 国产亚洲视频在线观看网址| 成人三级视频在线观看一区二区| 国产无遮挡又黄又爽在线观看| 黑人大荫蒂老太大| 国产精品成人国产乱| 国产精品无码专区久久久| 国产在线观看精品一区二区三区| 黑人又粗又大又硬a片| 国产成人精品午夜福利不卡| 黄a大片av永久免费| 免费国精产品—品二品| 天堂а√中文最新版地址在线| 免费看成人午夜福利专区| 国产高清露脸孕妇系列| 三级特黄60分钟在线观看| 亚洲一区二区三区影院| 午夜时刻免费入口| 免费视频成人片在线观看| 一本清日本在线视频精品| 国内精品久久久久影院日本| 少妇下面好紧好多水真爽播放| 亚洲精品国产熟女久久久| 日本妇人成熟免费中文字幕| 免费无码又爽又刺激毛片| 欧美噜噜久久久xxx| 巨爆乳无码视频在线观看| 自拍偷在线精品自拍偷99| 天天爽天天狠久久久综合麻豆 | 国产美女口爆吞精普通话| 女人被男人躁得好爽免费视频| 国产精品自产拍在线观看|