在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Protein tyrosine phosphatase type IVA 3 (Ptp4a3)

Recombinant Mouse Protein tyrosine phosphatase type IVA 3 (Ptp4a3)

  • 中文名稱：
    小鼠Ptp4a3重組蛋白
  • 貨號：
    CSB-YP887531MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Ptp4a3重組蛋白
  • 貨號：
    CSB-EP887531MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Ptp4a3重組蛋白
  • 貨號：
    CSB-EP887531MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Ptp4a3重組蛋白
  • 貨號：
    CSB-BP887531MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Ptp4a3重組蛋白
  • 貨號：
    CSB-MP887531MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Ptp4a3; Prl3; Protein tyrosine phosphatase type IVA 3; EC 3.1.3.48; Protein-tyrosine phosphatase 4a3; Protein-tyrosine phosphatase of regenerating liver 3; PRL-3
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-170
  • 氨基酸序列
    MARMNRPAPV EVSYRHMRFL ITHNPSNATL STFIEDLKKY GATTVVRVCE VTYDKTPLEK DGITVVDWPF DDGAPPPGKV VEDWLSLLKA KFYNDPGSCV AVHCVAGLGR APVLVALALI ESGMKYEDAI QFIRQKRRGA INSKQLTYLE KYRPKQRLRF KDPHTHKTRC
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II.
  • 基因功能參考文獻：
    1. our results suggest that the Prl3b1-cre mice line provides a unique resource to understand testicular germ-cell development PMID: 27124574
    2. Results demonstrate that Ptp4a3 contributes to the malignant phenotype of tumor-initiating cells. PMID: 24950307
    3. PRL-3 protein was significantly reduced in mouse STAT3-knockout liver cells compared with STAT3-wild type counterparts, and ectopic expression of STAT3 in these cells led to a pronounced increase in PRL-3 protein. PMID: 25139404
    4. Data indicate that Mycobacterium tuberculosis T cell stimulatory epitope (MT) is a potentially effective molecular adjuvant in preparation of monoclonal antibody (mAb) specific for phosphatase of regenerating liver-3 (PRL-3). PMID: 24909283
    5. These findings strongly support a role for PTP4A3 as an important contributor to endothelial cell function and as a multimodal target for cancer therapy and mitigating VEGF-regulated angiogenesis. PMID: 24403062
    6. the first definitive evidence implicating Ptp4a3 in colon tumorigenesis PMID: 23555575
    7. role of PTP4A3 in acute myeloid leukemia PMID: 22028901
    8. PTP4A3 was identified as a novel negative regulator of LPS-induced LITAF/TNF-alpha production. PMID: 20375622
    9. PRL-3 was highly expressed in metastatic melanoma B16-BL6 cells but not in its lowly metastatic parental cell line, B16 cells PMID: 15161639
    10. PRL-3-expressing cells rapidly induce metastatic tumor formation in lung PMID: 15326366
    11. expression is associated with gastric cancer metastases PMID: 16875667
    12. PRL-3 was shown to be expressed in the total mouse bone marrow fraction and more intensely in the Ter119-positive (pre-erythrocyte) fraction but not in the CD61-positive (megakaryocyte)fraction. PMID: 17018620
    13. Results suggest that Prl-3 plays a critical role in promoting the process of sponatneous metastasis and tumor growth initiation, and that inhibiting Prl-3 will improve melanoma therapy. PMID: 17592549
    14. Results identify Prl-3 (phosphatase of regenerating liver-3) as a p53-inducible gene, and demonstrate that Prl-3 is an important cell-cycle regulator. PMID: 18471976

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane. Early endosome.
  • 蛋白家族：
    Protein-tyrosine phosphatase family
  • 組織特異性：
    Present in the small intestine, where it is located in the differentiated epithelial cells of the villus but not in the proliferating crypt cells (at protein level). Expressed in heart and skeletal muscle, and at lower levels in lung, spleen and testis.
  • 數據庫鏈接：


主站蜘蛛池模板： 装睡被陌生人摸出水好爽| 国产精品无码av在线播放| 亚洲另类无码一区二区三区| 福利视频在线播放| 久久午夜私人影院| 天天爱天天做久久狼狼| 国产美女在线精品免费观看网址| 99久久综合狠狠综合久久| 亚洲色成人网站永久| 久久只精品99品免费久23| 亚洲国产精品成人午夜在线观看| 国产内射合集颜射| 国产亚洲精品无码不卡| 亚洲精品久久久久一区二区三区 | 久久久久久国产精品免费免费男同| 最新网站亚洲人成无码| 国产在线98福利播放视频| 精品熟女日韩中文十区| 人妻无码一区二区三区免费| 波多老师无码av中字专区 | 日本少妇三级hd激情在线观看| 久久人人97超碰国产公开| 欧美乱妇高清无乱码在线观看| 亚洲一区激情校园小说| 精品午夜中文字幕熟女人妻在线| 欧美成人国产精品高潮| 国产成人av大片大片在线播放| 国产精品最新免费视频| 日本xxxx18野外无毒不卡| 无套内射极品少妇chinese| 国产美女被遭高潮免费视频| 亚洲中文字幕第一页在线| 国产成人av男人的天堂| 国产午夜精品一区二区三区嫩草| 国产亚洲香蕉线播放αv38| 巨乳美乳一区二区三区| 永久免费的av在线电影网无码| 亚洲日本va午夜中文字幕久久| 精品国产电影久久九九| 成人免费无码av| 成年日韩片av在线网站|